BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 20687496)

  • 1. Spinocerebellar ataxia with axonal neuropathy.
    Walton C; Interthal H; Hirano R; Salih MA; Takashima H; Boerkoel CF
    Adv Exp Med Biol; 2010; 685():75-83. PubMed ID: 20687496
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tyrosyl-DNA phosphodiesterase I catalytic mutants reveal an alternative nucleophile that can catalyze substrate cleavage.
    Comeaux EQ; Cuya SM; Kojima K; Jafari N; Wanzeck KC; Mobley JA; Bjornsti MA; van Waardenburg RC
    J Biol Chem; 2015 Mar; 290(10):6203-14. PubMed ID: 25609251
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1.
    El-Khamisy SF; Saifi GM; Weinfeld M; Johansson F; Helleday T; Lupski JR; Caldecott KW
    Nature; 2005 Mar; 434(7029):108-13. PubMed ID: 15744309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes.
    Miao ZH; Agama K; Sordet O; Povirk L; Kohn KW; Pommier Y
    DNA Repair (Amst); 2006 Dec; 5(12):1489-94. PubMed ID: 16935573
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation.
    Hawkins AJ; Subler MA; Akopiants K; Wiley JL; Taylor SM; Rice AC; Windle JJ; Valerie K; Povirk LF
    DNA Repair (Amst); 2009 May; 8(5):654-63. PubMed ID: 19211312
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?
    Hirano R; Interthal H; Huang C; Nakamura T; Deguchi K; Choi K; Bhattacharjee MB; Arimura K; Umehara F; Izumo S; Northrop JL; Salih MA; Inoue K; Armstrong DL; Champoux JJ; Takashima H; Boerkoel CF
    EMBO J; 2007 Nov; 26(22):4732-43. PubMed ID: 17948061
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy.
    Takashima H; Boerkoel CF; John J; Saifi GM; Salih MA; Armstrong D; Mao Y; Quiocho FA; Roa BB; Nakagawa M; Stockton DW; Lupski JR
    Nat Genet; 2002 Oct; 32(2):267-72. PubMed ID: 12244316
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA single-strand break repair and spinocerebellar ataxia with axonal neuropathy-1.
    el-Khamisy SF; Caldecott KW
    Neuroscience; 2007 Apr; 145(4):1260-6. PubMed ID: 17045754
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tyrosyl-DNA phosphodiesterase (Tdp1) (3'-phosphotyrosyl DNA phosphodiesterase).
    Raymond AC; Burgin AB
    Methods Enzymol; 2006; 409():511-24. PubMed ID: 16793421
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.
    Comeaux EQ; van Waardenburg RC
    Drug Metab Rev; 2014 Nov; 46(4):494-507. PubMed ID: 25327705
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.
    Interthal H; Chen HJ; Champoux JJ
    J Biol Chem; 2005 Oct; 280(43):36518-28. PubMed ID: 16141202
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1).
    Zhou T; Lee JW; Tatavarthi H; Lupski JR; Valerie K; Povirk LF
    Nucleic Acids Res; 2005; 33(1):289-97. PubMed ID: 15647511
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity.
    Interthal H; Chen HJ; Kehl-Fie TE; Zotzmann J; Leppard JB; Champoux JJ
    EMBO J; 2005 Jun; 24(12):2224-33. PubMed ID: 15920477
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.
    Liu C; Pouliot JJ; Nash HA
    Proc Natl Acad Sci U S A; 2002 Nov; 99(23):14970-5. PubMed ID: 12397185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.
    Nitiss KC; Malik M; He X; White SW; Nitiss JL
    Proc Natl Acad Sci U S A; 2006 Jun; 103(24):8953-8. PubMed ID: 16751265
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
    Zeng Z; Sharma A; Ju L; Murai J; Umans L; Vermeire L; Pommier Y; Takeda S; Huylebroeck D; Caldecott KW; El-Khamisy SF
    Nucleic Acids Res; 2012 Sep; 40(17):8371-80. PubMed ID: 22740648
    [TBL] [Abstract][Full Text] [Related]  

  • 17. UCHL3 Regulates Topoisomerase-Induced Chromosomal Break Repair by Controlling TDP1 Proteostasis.
    Liao C; Beveridge R; Hudson JJR; Parker JD; Chiang SC; Ray S; Ashour ME; Sudbery I; Dickman MJ; El-Khamisy SF
    Cell Rep; 2018 Jun; 23(11):3352-3365. PubMed ID: 29898404
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair.
    Hudson JJ; Chiang SC; Wells OS; Rookyard C; El-Khamisy SF
    Nat Commun; 2012 Mar; 3():733. PubMed ID: 22415824
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks.
    Zhou T; Akopiants K; Mohapatra S; Lin PS; Valerie K; Ramsden DA; Lees-Miller SP; Povirk LF
    DNA Repair (Amst); 2009 Aug; 8(8):901-11. PubMed ID: 19505854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy.
    Ghosh A; Bhattacharjee S; Chowdhuri SP; Mallick A; Rehman I; Basu S; Das BB
    Sci Adv; 2019 Nov; 5(11):eaax9778. PubMed ID: 31723605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.