152 related articles for article (PubMed ID: 20695530)
1. Chemical basis for the selectivity of the von Hippel Lindau tumor suppressor pVHL for prolyl-hydroxylated HIF-1alpha.
Illingworth CJ; Loenarz C; Schofield CJ; Domene C
Biochemistry; 2010 Aug; 49(32):6936-44. PubMed ID: 20695530
[TBL] [Abstract][Full Text] [Related]
2. Quantifying the Binding Interaction between the Hypoxia-Inducible Transcription Factor and the von Hippel-Lindau Suppressor.
Domene C; Jorgensen C; Vanommeslaeghe K; Schofield CJ; MacKerell A
J Chem Theory Comput; 2015 Aug; 11(8):3946-54. PubMed ID: 26574473
[TBL] [Abstract][Full Text] [Related]
3. Proline hydroxylation at different sites in hypoxia-inducible factor 1α modulates its interactions with the von Hippel-Lindau tumor suppressor protein.
Qian H; Zou Y; Tang Y; Gong Y; Qian Z; Wei G; Zhang Q
Phys Chem Chem Phys; 2018 Jul; 20(27):18756-18765. PubMed ID: 29961792
[TBL] [Abstract][Full Text] [Related]
4. In silico investigation of PHD-3 specific HIF1-α proline 567 hydroxylation: a new player in the VHL/HIF-1α interaction pathway?
Minervini G; Masiero A; Moro S; Tosatto SC
FEBS Lett; 2013 Sep; 587(18):2996-3001. PubMed ID: 23886708
[TBL] [Abstract][Full Text] [Related]
5. Simulation of the mutation F76del on the von Hippel-Lindau tumor suppressor protein: mechanism of the disease and implications for drug development.
Limaverde-Sousa G; Barreto Ede A; Ferreira CG; Casali-da-Rocha JC
Proteins; 2013 Feb; 81(2):349-63. PubMed ID: 23011899
[TBL] [Abstract][Full Text] [Related]
6. Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL.
Hon WC; Wilson MI; Harlos K; Claridge TD; Schofield CJ; Pugh CW; Maxwell PH; Ratcliffe PJ; Stuart DI; Jones EY
Nature; 2002 Jun; 417(6892):975-8. PubMed ID: 12050673
[TBL] [Abstract][Full Text] [Related]
7. Effects of point mutations in pVHL on the binding of HIF-1α.
Domene C; Illingworth CJ
Proteins; 2012 Mar; 80(3):733-46. PubMed ID: 22105711
[TBL] [Abstract][Full Text] [Related]
8. Evidence for a stereoelectronic effect in human oxygen sensing.
Loenarz C; Mecinović J; Chowdhury R; McNeill LA; Flashman E; Schofield CJ
Angew Chem Int Ed Engl; 2009; 48(10):1784-7. PubMed ID: 19180614
[TBL] [Abstract][Full Text] [Related]
9. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing.
Mole DR; Maxwell PH; Pugh CW; Ratcliffe PJ
IUBMB Life; 2001 Jul; 52(1-2):43-7. PubMed ID: 11795592
[TBL] [Abstract][Full Text] [Related]
10. HIF-1alpha peptide derivatives with modifications at the hydroxyproline residue as activators of HIF-1alpha.
Ahn DR; Kim SY; Lee MJ; Yang EG
Bioorg Med Chem Lett; 2009 Aug; 19(15):4403-5. PubMed ID: 19515556
[TBL] [Abstract][Full Text] [Related]
11. von Hippel-Lindau β-domain-luciferase fusion protein as a bioluminescent hydroxyproline sensor for a hypoxia-inducible factor prolyl hydroxylase assay.
Hong S; Yum S; Ha NC; Jung Y
Anal Biochem; 2010 Dec; 407(2):220-5. PubMed ID: 20705044
[TBL] [Abstract][Full Text] [Related]
12. Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design.
Liu J; Nussinov R
Proc Natl Acad Sci U S A; 2008 Jan; 105(3):901-6. PubMed ID: 18195360
[TBL] [Abstract][Full Text] [Related]
13. Hydroxylation-Dependent Interaction of Substrates to the Von Hippel-Lindau Tumor Suppressor Protein (VHL).
Heir P; Ohh M
Methods Mol Biol; 2016; 1458():87-94. PubMed ID: 27581016
[TBL] [Abstract][Full Text] [Related]
14. von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase.
Li SH; Chun YS; Lim JH; Huang LE; Park JW
Int J Biochem Cell Biol; 2011 May; 43(5):795-804. PubMed ID: 21316481
[TBL] [Abstract][Full Text] [Related]
15. Alternative regulation of HIF-1α stability through Phosphorylation on Ser451.
Han HJ; Saeidi S; Kim SJ; Piao JY; Lim S; Guillen-Quispe YN; Choi BY; Surh YJ
Biochem Biophys Res Commun; 2021 Mar; 545():150-156. PubMed ID: 33550096
[TBL] [Abstract][Full Text] [Related]
16. Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.
Park YK; Ahn DR; Oh M; Lee T; Yang EG; Son M; Park H
Mol Pharmacol; 2008 Jul; 74(1):236-45. PubMed ID: 18426857
[TBL] [Abstract][Full Text] [Related]
17. Structure of an HIF-1alpha -pVHL complex: hydroxyproline recognition in signaling.
Min JH; Yang H; Ivan M; Gertler F; Kaelin WG; Pavletich NP
Science; 2002 Jun; 296(5574):1886-9. PubMed ID: 12004076
[TBL] [Abstract][Full Text] [Related]
18. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
Jaakkola P; Mole DR; Tian YM; Wilson MI; Gielbert J; Gaskell SJ; von Kriegsheim A; Hebestreit HF; Mukherji M; Schofield CJ; Maxwell PH; Pugh CW; Ratcliffe PJ
Science; 2001 Apr; 292(5516):468-72. PubMed ID: 11292861
[TBL] [Abstract][Full Text] [Related]
19. Homology modeling and molecular dynamics simulation of the HIF2α degradation-related HIF2α-VHL complex.
Dong X; Su X; Yu J; Liu J; Shi X; Pan Q; Yang J; Chen J; Li L; Cao H
J Mol Graph Model; 2017 Jan; 71():116-123. PubMed ID: 27902963
[TBL] [Abstract][Full Text] [Related]
20. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
Chowdhury R; McDonough MA; Mecinović J; Loenarz C; Flashman E; Hewitson KS; Domene C; Schofield CJ
Structure; 2009 Jul; 17(7):981-9. PubMed ID: 19604478
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
