BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 20696268)

  • 1. DNA polymerase structure-based insight on the mutagenic properties of 8-oxoguanine.
    Beard WA; Batra VK; Wilson SH
    Mutat Res; 2010 Nov; 703(1):18-23. PubMed ID: 20696268
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binary complex crystal structure of DNA polymerase β reveals multiple conformations of the templating 8-oxoguanine lesion.
    Batra VK; Shock DD; Beard WA; McKenna CE; Wilson SH
    Proc Natl Acad Sci U S A; 2012 Jan; 109(1):113-8. PubMed ID: 22178760
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion.
    Freudenthal BD; Beard WA; Wilson SH
    Nucleic Acids Res; 2013 Feb; 41(3):1848-58. PubMed ID: 23267011
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential.
    Krahn JM; Beard WA; Miller H; Grollman AP; Wilson SH
    Structure; 2003 Jan; 11(1):121-7. PubMed ID: 12517346
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide.
    Freudenthal BD; Beard WA; Perera L; Shock DD; Kim T; Schlick T; Wilson SH
    Nature; 2015 Jan; 517(7536):635-9. PubMed ID: 25409153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site.
    Batra VK; Beard WA; Hou EW; Pedersen LC; Prasad R; Wilson SH
    Nat Struct Mol Biol; 2010 Jul; 17(7):889-90. PubMed ID: 20526335
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion.
    Vasquez-Del Carpio R; Silverstein TD; Lone S; Swan MK; Choudhury JR; Johnson RE; Prakash S; Prakash L; Aggarwal AK
    PLoS One; 2009 Jun; 4(6):e5766. PubMed ID: 19492058
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4.
    Jung H; Lee S
    Biochem J; 2020 Aug; 477(15):2859-2871. PubMed ID: 32686822
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
    Beckman J; Wang M; Blaha G; Wang J; Konigsberg WH
    Biochemistry; 2010 May; 49(19):4116-25. PubMed ID: 20411947
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.
    Kou Y; Koag MC; Lee S
    Molecules; 2019 Sep; 24(19):. PubMed ID: 31569643
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The anti/syn conformation of 8-oxo-7,8-dihydro-2'-deoxyguanosine is modulated by Bacillus subtilis PolX active site residues His255 and Asn263. Efficient processing of damaged 3'-ends.
    Zafra O; Pérez de Ayala L; de Vega M
    DNA Repair (Amst); 2017 Apr; 52():59-69. PubMed ID: 28254425
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences.
    Perlow RA; Broyde S
    J Mol Biol; 2002 Sep; 322(2):291-309. PubMed ID: 12217692
    [TBL] [Abstract][Full Text] [Related]  

  • 13. How DNA polymerase X preferentially accommodates incoming dATP opposite 8-oxoguanine on the template.
    Sampoli Benítez B; Barbati ZR; Arora K; Bogdanovic J; Schlick T
    Biophys J; 2013 Dec; 105(11):2559-68. PubMed ID: 24314086
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.
    Kirouac KN; Ling H
    Proc Natl Acad Sci U S A; 2011 Feb; 108(8):3210-5. PubMed ID: 21300901
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.
    Perlow RA; Broyde S
    J Mol Biol; 2001 Jun; 309(2):519-36. PubMed ID: 11371169
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Polymerases.
    Koag MC; Jung H; Lee S
    J Am Chem Soc; 2019 Mar; 141(11):4584-4596. PubMed ID: 30817143
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.
    Rechkoblit O; Malinina L; Cheng Y; Geacintov NE; Broyde S; Patel DJ
    Structure; 2009 May; 17(5):725-36. PubMed ID: 19446528
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta.
    Brown JA; Duym WW; Fowler JD; Suo Z
    J Mol Biol; 2007 Apr; 367(5):1258-69. PubMed ID: 17321545
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η.
    Patra A; Nagy LD; Zhang Q; Su Y; Müller L; Guengerich FP; Egli M
    J Biol Chem; 2014 Jun; 289(24):16867-82. PubMed ID: 24759104
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.
    Perlow RA; Broyde S
    J Mol Biol; 2003 Apr; 327(4):797-818. PubMed ID: 12654264
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.