172 related articles for article (PubMed ID: 20697760)
1. Structure-based in-silico rational design of a selective peptide inhibitor for thymidine monophosphate kinase of mycobacterium tuberculosis.
Kumar M; Sharma S; Srinivasan A; Singh TP; Kaur P
J Mol Model; 2011 May; 17(5):1173-82. PubMed ID: 20697760
[TBL] [Abstract][Full Text] [Related]
2. Computer-assisted combinatorial design of bicyclic thymidine analogs as inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Frecer V; Seneci P; Miertus S
J Comput Aided Mol Des; 2011 Jan; 25(1):31-49. PubMed ID: 21082329
[TBL] [Abstract][Full Text] [Related]
3. Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents.
Song L; Risseeuw MDP; Froeyen M; Karalic I; Goeman J; Cappoen D; Van der Eycken J; Cos P; Munier-Lehmann H; Van Calenbergh S
Bioorg Med Chem; 2016 Nov; 24(21):5172-5182. PubMed ID: 27614917
[TBL] [Abstract][Full Text] [Related]
4. Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Vanheusden V; Munier-Lehmann H; Froeyen M; Busson R; Rozenski J; Herdewijn P; Van Calenbergh S
J Med Chem; 2004 Dec; 47(25):6187-94. PubMed ID: 15566289
[TBL] [Abstract][Full Text] [Related]
5. Rational design and 3D-pharmacophore mapping of 5'-thiourea-substituted alpha-thymidine analogues as mycobacterial TMPK inhibitors.
Andrade CH; Pasqualoto KF; Ferreira EI; Hopfinger AJ
J Chem Inf Model; 2009 Apr; 49(4):1070-8. PubMed ID: 19296716
[TBL] [Abstract][Full Text] [Related]
6. The crystal structure of Mycobacterium tuberculosis thymidylate kinase in complex with 3'-azidodeoxythymidine monophosphate suggests a mechanism for competitive inhibition.
Fioravanti E; Adam V; Munier-Lehmann H; Bourgeois D
Biochemistry; 2005 Jan; 44(1):130-7. PubMed ID: 15628853
[TBL] [Abstract][Full Text] [Related]
7. Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth.
Van Daele I; Munier-Lehmann H; Froeyen M; Balzarini J; Van Calenbergh S
J Med Chem; 2007 Nov; 50(22):5281-92. PubMed ID: 17910427
[TBL] [Abstract][Full Text] [Related]
8. Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.
Munier-Lehmann H; Pochet S; Dugue L; Dutruel O; Labesse G; Douget D
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):801-4. PubMed ID: 14565282
[No Abstract] [Full Text] [Related]
9. In silico structure-based design of a novel class of potent and selective small peptide inhibitor of Mycobacterium tuberculosis Dihydrofolate reductase, a potential target for anti-TB drug discovery.
Kumar M; Vijayakrishnan R; Subba Rao G
Mol Divers; 2010 Aug; 14(3):595-604. PubMed ID: 19697148
[TBL] [Abstract][Full Text] [Related]
10. 3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.
Aparna V; Jeevan J; Ravi M; Desiraju GR; Gopalakrishnan B
Bioorg Med Chem Lett; 2006 Feb; 16(4):1014-20. PubMed ID: 16290929
[TBL] [Abstract][Full Text] [Related]
11. Structural and chemical basis for enhanced affinity to a series of mycobacterial thymidine monophosphate kinase inhibitors: fragment-based QSAR and QM/MM docking studies.
Bueno RV; Toledo NR; Neves BJ; Braga RC; Andrade CH
J Mol Model; 2013 Jan; 19(1):179-92. PubMed ID: 22846924
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Vanheusden V; Munier-Lehmann H; Pochet S; Herdewijn P; Van Calenbergh S
Bioorg Med Chem Lett; 2002 Oct; 12(19):2695-8. PubMed ID: 12217356
[TBL] [Abstract][Full Text] [Related]
13. Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Vanheusden V; Van Rompaey P; Munier-Lehmann H; Pochet S; Herdewijn P; Van Calenbergh S
Bioorg Med Chem Lett; 2003 Sep; 13(18):3045-8. PubMed ID: 12941330
[TBL] [Abstract][Full Text] [Related]
14. 1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors.
Jian Y; Hulpia F; D P Risseeuw M; Forbes HE; Caljon G; Munier-Lehmann H; I M Boshoff H; Van Calenbergh S
Molecules; 2020 Jun; 25(12):. PubMed ID: 32560578
[TBL] [Abstract][Full Text] [Related]
15. 3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Vanheusden V; Munier-Lehmann H; Froeyen M; Dugué L; Heyerick A; De Keukeleire D; Pochet S; Busson R; Herdewijn P; Van Calenbergh S
J Med Chem; 2003 Aug; 46(18):3811-21. PubMed ID: 12930144
[TBL] [Abstract][Full Text] [Related]
16. Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors.
Song L; Merceron R; Gracia B; Quintana AL; Risseeuw MDP; Hulpia F; Cos P; Aínsa JA; Munier-Lehmann H; Savvides SN; Van Calenbergh S
J Med Chem; 2018 Apr; 61(7):2753-2775. PubMed ID: 29510037
[TBL] [Abstract][Full Text] [Related]
17. 3D-Pharmacophore mapping of thymidine-based inhibitors of TMPK as potential antituberculosis agents.
Andrade CH; Pasqualoto KF; Ferreira EI; Hopfinger AJ
J Comput Aided Mol Des; 2010 Feb; 24(2):157-72. PubMed ID: 20217185
[TBL] [Abstract][Full Text] [Related]
18. A new family of inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase.
Gasse C; Huteau V; Douguet D; Munier-Lehmann H; Pochet S
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1057-61. PubMed ID: 18058536
[No Abstract] [Full Text] [Related]
19. Computational Overview of Mycobacterial Thymidine Monophosphate Kinase.
Gul S; Khalil R; Zaheer Ul-Haq ; Mubarak MS
Curr Pharm Des; 2020; 26(15):1676-1681. PubMed ID: 32242781
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase.
Van Poecke S; Munier-Lehmann H; Helynck O; Froeyen M; Van Calenbergh S
Bioorg Med Chem; 2011 Dec; 19(24):7603-11. PubMed ID: 22061826
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]