BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

430 related articles for article (PubMed ID: 20699324)

  • 1. Constitutive activity of serotonin 2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants.
    Labasque M; Meffre J; Carrat G; Becamel C; Bockaert J; Marin P
    Mol Pharmacol; 2010 Nov; 78(5):818-26. PubMed ID: 20699324
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction.
    Chanrion B; Mannoury la Cour C; Gavarini S; Seimandi M; Vincent L; Pujol JF; Bockaert J; Marin P; Millan MJ
    Mol Pharmacol; 2008 Mar; 73(3):748-57. PubMed ID: 18083778
    [TBL] [Abstract][Full Text] [Related]  

  • 3. S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization.
    Millan MJ; Mannoury la Cour C; Chanrion B; Dupuis DS; Di Cara B; Audinot V; Cussac D; Newman-Tancredi A; Kamal M; Boutin JA; Jockers R; Marin P; Bockaert J; Muller O; Dekeyne A; Lavielle G
    J Pharmacol Exp Ther; 2012 Mar; 340(3):750-64. PubMed ID: 22178752
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT(2C) receptors.
    Millan MJ; Marin P; Kamal M; Jockers R; Chanrion B; Labasque M; Bockaert J; Mannoury la Cour C
    Int J Neuropsychopharmacol; 2011 Jul; 14(6):768-83. PubMed ID: 20946699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.
    Labasque M; Reiter E; Becamel C; Bockaert J; Marin P
    Mol Biol Cell; 2008 Nov; 19(11):4640-50. PubMed ID: 18768750
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Serotonin 5-HT(2C) receptor homodimerization is not regulated by agonist or inverse agonist treatment.
    Herrick-Davis K; Grinde E; Weaver BA
    Eur J Pharmacol; 2007 Jul; 568(1-3):45-53. PubMed ID: 17507008
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacology of 5HT(2C) receptor-mediated ERK1/2 phosphorylation: agonist-specific activation pathways and the impact of RNA editing.
    Werry TD; Stewart GD; Crouch MF; Watts A; Sexton PM; Christopoulos A
    Biochem Pharmacol; 2008 Nov; 76(10):1276-87. PubMed ID: 18812172
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease.
    Navailles S; Lagière M; Roumegous A; Polito M; Boujema MB; Cador M; Dunlop J; Chesselet MF; Millan MJ; De Deurwaerdère P
    Int J Neuropsychopharmacol; 2013 Apr; 16(3):593-606. PubMed ID: 22717119
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling.
    Berg KA; Dunlop J; Sanchez T; Silva M; Clarke WP
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1084-92. PubMed ID: 18065501
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization.
    Thomsen WJ; Grottick AJ; Menzaghi F; Reyes-Saldana H; Espitia S; Yuskin D; Whelan K; Martin M; Morgan M; Chen W; Al-Shamma H; Smith B; Chalmers D; Behan D
    J Pharmacol Exp Ther; 2008 May; 325(2):577-87. PubMed ID: 18252809
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts.
    Olianas MC; Dedoni S; Onali P
    Biochem Pharmacol; 2015 Jun; 95(4):311-23. PubMed ID: 25888927
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction.
    Herrick-Davis K; Grinde E; Niswender CM
    J Neurochem; 1999 Oct; 73(4):1711-7. PubMed ID: 10501219
    [TBL] [Abstract][Full Text] [Related]  

  • 13. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor.
    Shenoy SK; Drake MT; Nelson CD; Houtz DA; Xiao K; Madabushi S; Reiter E; Premont RT; Lichtarge O; Lefkowitz RJ
    J Biol Chem; 2006 Jan; 281(2):1261-73. PubMed ID: 16280323
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2.
    Werry TD; Gregory KJ; Sexton PM; Christopoulos A
    J Neurochem; 2005 Jun; 93(6):1603-15. PubMed ID: 15935077
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Techniques for studying inverse agonist activity of antidepressants at recombinant nonedited 5-HT(₂C-INI) receptor and native neuronal 5-HT(₂C) receptors.
    Seimandi M; Bockaert J; Marin P
    Methods Enzymol; 2010; 485():61-79. PubMed ID: 21050911
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on beta-arrestin translocation or receptor endocytosis.
    Gripentrog JM; Miettinen HM
    Cell Signal; 2005 Oct; 17(10):1300-11. PubMed ID: 16038804
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNA editing of the serotonin 2C receptor and expression of Galpha(q) protein: genetic mouse models do not support a role for regulation or compensation.
    Canal CE; Mahautmr KC; Cao C; Sanders-Bush E; Airey DC
    J Neurochem; 2009 Mar; 108(5):1136-42. PubMed ID: 19154337
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of serotonin-2C receptor G-protein coupling by RNA editing.
    Burns CM; Chu H; Rueter SM; Hutchinson LK; Canton H; Sanders-Bush E; Emeson RB
    Nature; 1997 May; 387(6630):303-8. PubMed ID: 9153397
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of vabicaserin (SCA-136), a selective 5-hydroxytryptamine 2C receptor agonist.
    Dunlop J; Watts SW; Barrett JE; Coupet J; Harrison B; Mazandarani H; Nawoschik S; Pangalos MN; Ramamoorthy S; Schechter L; Smith D; Stack G; Zhang J; Zhang G; Rosenzweig-Lipson S
    J Pharmacol Exp Ther; 2011 Jun; 337(3):673-80. PubMed ID: 21402690
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity.
    Berg KA; Cropper JD; Niswender CM; Sanders-Bush E; Emeson RB; Clarke WP
    Br J Pharmacol; 2001 Sep; 134(2):386-92. PubMed ID: 11564657
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.