BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 20699475)

  • 1. The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development.
    Ramadani F; Bolland DJ; Garcon F; Emery JL; Vanhaesebroeck B; Corcoran AE; Okkenhaug K
    Sci Signal; 2010 Aug; 3(134):ra60. PubMed ID: 20699475
    [TBL] [Abstract][Full Text] [Related]  

  • 2. B cell receptor signaling: picky about PI3Ks.
    Limon JJ; Fruman DA
    Sci Signal; 2010 Aug; 3(134):pe25. PubMed ID: 20699473
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Requirement for phosphoinositide 3-kinase p110delta signaling in B cell antigen receptor-mediated antigen presentation.
    Al-Alwan MM; Okkenhaug K; Vanhaesebroeck B; Hayflick JS; Marshall AJ
    J Immunol; 2007 Feb; 178(4):2328-35. PubMed ID: 17277138
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Class IA Phosphatidylinositol 3-Kinase Isoform p110α Mediates Vascular Remodeling.
    Vantler M; Jesus J; Leppänen O; Scherner M; Berghausen EM; Mustafov L; Chen X; Kramer T; Zierden M; Gerhardt M; Ten Freyhaus H; Blaschke F; Sterner-Kock A; Baldus S; Zhao JJ; Rosenkranz S
    Arterioscler Thromb Vasc Biol; 2015 Jun; 35(6):1434-44. PubMed ID: 25908763
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.
    Beer-Hammer S; Zebedin E; von Holleben M; Alferink J; Reis B; Dresing P; Degrandi D; Scheu S; Hirsch E; Sexl V; Pfeffer K; Nürnberg B; Piekorz RP
    J Leukoc Biol; 2010 Jun; 87(6):1083-95. PubMed ID: 20200404
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Analysis of the individual contributions of Igalpha (CD79a)- and Igbeta (CD79b)-mediated tonic signaling for bone marrow B cell development and peripheral B cell maturation.
    Fuentes-Pananá EM; Bannish G; Karnell FG; Treml JF; Monroe JG
    J Immunol; 2006 Dec; 177(11):7913-22. PubMed ID: 17114463
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Key role of the p110delta isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110delta function in B cells.
    Bilancio A; Okkenhaug K; Camps M; Emery JL; Ruckle T; Rommel C; Vanhaesebroeck B
    Blood; 2006 Jan; 107(2):642-50. PubMed ID: 16179367
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes.
    Glassford J; Vigorito E; Soeiro I; Madureira PA; Zoumpoulidou G; Brosens JJ; Turner M; Lam EW
    Eur J Immunol; 2005 Sep; 35(9):2748-61. PubMed ID: 16114097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse.
    Iyengar S; Clear A; Bödör C; Maharaj L; Lee A; Calaminici M; Matthews J; Iqbal S; Auer R; Gribben J; Joel S
    Blood; 2013 Mar; 121(12):2274-84. PubMed ID: 23341541
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The PI3K p110delta is required for down-regulation of RAG expression in immature B cells.
    Llorian M; Stamataki Z; Hill S; Turner M; Mårtensson IL
    J Immunol; 2007 Feb; 178(4):1981-5. PubMed ID: 17277100
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of PI3K in the generation and survival of B cells.
    Werner M; Hobeika E; Jumaa H
    Immunol Rev; 2010 Sep; 237(1):55-71. PubMed ID: 20727029
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of P110α and P110δ catalytic subunits of PI3 kinase reverses impaired arterial healing after injury in hypercholesterolemic male mice.
    Chaudhuri P; Smith AH; Graham LM; Rosenbaum MA
    Am J Physiol Cell Physiol; 2021 Jun; 320(6):C943-C955. PubMed ID: 33689479
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function.
    So L; Yea SS; Oak JS; Lu M; Manmadhan A; Ke QH; Janes MR; Kessler LV; Kucharski JM; Li LS; Martin MB; Ren P; Jessen KA; Liu Y; Rommel C; Fruman DA
    J Biol Chem; 2013 Feb; 288(8):5718-31. PubMed ID: 23275335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthetic biology of B cell activation: understanding signal amplification at the B cell antigen receptor using a rebuilding approach.
    Kulathu Y; Zuern C; Yang J; Reth M
    Biol Chem; 2019 Mar; 400(4):555-563. PubMed ID: 30465710
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.
    Okkenhaug K; Bilancio A; Farjot G; Priddle H; Sancho S; Peskett E; Pearce W; Meek SE; Salpekar A; Waterfield MD; Smith AJ; Vanhaesebroeck B
    Science; 2002 Aug; 297(5583):1031-4. PubMed ID: 12130661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.
    Papakonstanti EA; Zwaenepoel O; Bilancio A; Burns E; Nock GE; Houseman B; Shokat K; Ridley AJ; Vanhaesebroeck B
    J Cell Sci; 2008 Dec; 121(Pt 24):4124-33. PubMed ID: 19033389
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.
    Bednarski JJ; Pandey R; Schulte E; White LS; Chen BR; Sandoval GJ; Kohyama M; Haldar M; Nickless A; Trott A; Cheng G; Murphy KM; Bassing CH; Payton JE; Sleckman BP
    J Exp Med; 2016 Feb; 213(2):209-23. PubMed ID: 26834154
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activity of any class IA PI3K isoform can sustain cell proliferation and survival.
    Foukas LC; Berenjeno IM; Gray A; Khwaja A; Vanhaesebroeck B
    Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11381-6. PubMed ID: 20534549
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells.
    Janas ML; Hodson D; Stamataki Z; Hill S; Welch K; Gambardella L; Trotman LC; Pandolfi PP; Vigorito E; Turner M
    J Immunol; 2008 Jan; 180(2):739-46. PubMed ID: 18178811
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.
    Guillermet-Guibert J; Bjorklof K; Salpekar A; Gonella C; Ramadani F; Bilancio A; Meek S; Smith AJ; Okkenhaug K; Vanhaesebroeck B
    Proc Natl Acad Sci U S A; 2008 Jun; 105(24):8292-7. PubMed ID: 18544649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.