BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

323 related articles for article (PubMed ID: 20700484)

  • 1. NPRL2 sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin treatment by regulating key components in the DNA repair pathway.
    Jayachandran G; Ueda K; Wang B; Roth JA; Ji L
    PLoS One; 2010 Aug; 5(8):e11994. PubMed ID: 20700484
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.
    Pabla N; Huang S; Mi QS; Daniel R; Dong Z
    J Biol Chem; 2008 Mar; 283(10):6572-83. PubMed ID: 18162465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells.
    Ueda K; Kawashima H; Ohtani S; Deng WG; Ravoori M; Bankson J; Gao B; Girard L; Minna JD; Roth JA; Kundra V; Ji L
    Cancer Res; 2006 Oct; 66(19):9682-90. PubMed ID: 17018626
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resistance to DNA-damaging treatment in non-small cell lung cancer tumor-initiating cells involves reduced DNA-PK/ATM activation and diminished cell cycle arrest.
    Lundholm L; Hååg P; Zong D; Juntti T; Mörk B; Lewensohn R; Viktorsson K
    Cell Death Dis; 2013 Jan; 4(1):e478. PubMed ID: 23370278
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin.
    Shi Y; Felley-Bosco E; Marti TM; Orlowski K; Pruschy M; Stahel RA
    BMC Cancer; 2012 Dec; 12():571. PubMed ID: 23211021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.
    Reinhardt HC; Aslanian AS; Lees JA; Yaffe MB
    Cancer Cell; 2007 Feb; 11(2):175-89. PubMed ID: 17292828
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human monocytes undergo excessive apoptosis following temozolomide activating the ATM/ATR pathway while dendritic cells and macrophages are resistant.
    Bauer M; Goldstein M; Heylmann D; Kaina B
    PLoS One; 2012; 7(6):e39956. PubMed ID: 22768182
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G; Yao L; Ruan K; Song G; Mao Y; Bao S
    Cell Biol Int; 2009 Dec; 33(12):1237-44. PubMed ID: 19732843
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of Nitrogen Permease Regulator Like-2 (NPRL2) Enhances Sensitivity to Irinotecan (CPT-11) in Colon Cancer Cells by Activating the DNA Damage Checkpoint Pathway.
    Liu S; Liu B
    Med Sci Monit; 2018 Mar; 24():1424-1433. PubMed ID: 29519997
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation.
    Turner J; Koumenis C; Kute TE; Planalp RP; Brechbiel MW; Beardsley D; Cody B; Brown KD; Torti FM; Torti SV
    Blood; 2005 Nov; 106(9):3191-9. PubMed ID: 16014567
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.
    Jin J; Ang XL; Ye X; Livingstone M; Harper JW
    J Biol Chem; 2008 Jul; 283(28):19322-8. PubMed ID: 18480045
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Irradiation-induced G2/M checkpoint response requires ERK1/2 activation.
    Yan Y; Black CP; Cowan KH
    Oncogene; 2007 Jul; 26(32):4689-98. PubMed ID: 17297454
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.
    Shibata A; Barton O; Noon AT; Dahm K; Deckbar D; Goodarzi AA; Löbrich M; Jeggo PA
    Mol Cell Biol; 2010 Jul; 30(13):3371-83. PubMed ID: 20421415
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
    Agarwal C; Tyagi A; Agarwal R
    Mol Cancer Ther; 2006 Dec; 5(12):3294-302. PubMed ID: 17172433
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. S-phase checkpoints regulate Apo2 ligand/TRAIL and CPT-11-induced apoptosis of prostate cancer cells.
    Ray S; Shyam S; Fraizer GC; Almasan A
    Mol Cancer Ther; 2007 Apr; 6(4):1368-78. PubMed ID: 17431115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATM-Chk2-Cdc25A and ATM-p53-p21-pathways.
    Gaul L; Mandl-Weber S; Baumann P; Emmerich B; Schmidmaier R
    J Cancer Res Clin Oncol; 2008 Feb; 134(2):245-53. PubMed ID: 17653574
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest.
    Yong W; Bao S; Chen H; Li D; Sánchez ER; Shou W
    J Biol Chem; 2007 May; 282(20):14690-4. PubMed ID: 17376776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The involvement of ataxia-telangiectasia mutated protein activation in nucleotide excision repair-facilitated cell survival with cisplatin treatment.
    Colton SL; Xu XS; Wang YA; Wang G
    J Biol Chem; 2006 Sep; 281(37):27117-25. PubMed ID: 16849332
    [TBL] [Abstract][Full Text] [Related]  

  • 20. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA; Cragg MS; Davidson SM; McCormick J; Barry S; Lawrence KM; Knight RA; Hubank M; Chen PL; Latchman DS; Stephanou A
    J Cell Sci; 2005 Apr; 118(Pt 8):1629-39. PubMed ID: 15784679
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.