BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 20701602)

  • 1. The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells.
    Dai Y; Guzman ML; Chen S; Wang L; Yeung SK; Pei XY; Dent P; Jordan CT; Grant S
    Br J Haematol; 2010 Oct; 151(1):70-83. PubMed ID: 20701602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blockade of histone deacetylase inhibitor-induced RelA/p65 acetylation and NF-kappaB activation potentiates apoptosis in leukemia cells through a process mediated by oxidative damage, XIAP downregulation, and c-Jun N-terminal kinase 1 activation.
    Dai Y; Rahmani M; Dent P; Grant S
    Mol Cell Biol; 2005 Jul; 25(13):5429-44. PubMed ID: 15964800
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Resveratrol sensitizes acute myelogenous leukemia cells to histone deacetylase inhibitors through reactive oxygen species-mediated activation of the extrinsic apoptotic pathway.
    Yaseen A; Chen S; Hock S; Rosato R; Dent P; Dai Y; Grant S
    Mol Pharmacol; 2012 Dec; 82(6):1030-41. PubMed ID: 22923501
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF-κB and Bim.
    Dai Y; Chen S; Wang L; Pei XY; Kramer LB; Dent P; Grant S
    Br J Haematol; 2011 Apr; 153(2):222-35. PubMed ID: 21375523
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contribution of disruption of the nuclear factor-kappaB pathway to induction of apoptosis in human leukemia cells by histone deacetylase inhibitors and flavopiridol.
    Gao N; Dai Y; Rahmani M; Dent P; Grant S
    Mol Pharmacol; 2004 Oct; 66(4):956-63. PubMed ID: 15235103
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of IkappaB kinase (IKK)-mediated RelA serine 536 phosphorylation sensitizes human multiple myeloma cells to histone deacetylase (HDAC) inhibitors.
    Dai Y; Chen S; Wang L; Pei XY; Funk VL; Kramer LB; Dent P; Grant S
    J Biol Chem; 2011 Sep; 286(39):34036-50. PubMed ID: 21816815
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Histone deacetylase inhibitors activate NF-kappaB in human leukemia cells through an ATM/NEMO-related pathway.
    Rosato RR; Kolla SS; Hock SK; Almenara JA; Patel A; Amin S; Atadja P; Fisher PB; Dent P; Grant S
    J Biol Chem; 2010 Mar; 285(13):10064-10077. PubMed ID: 20065354
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK.
    Dai Y; Rahmani M; Pei XY; Khanna P; Han SI; Mitchell C; Dent P; Grant S
    Blood; 2005 Feb; 105(4):1706-16. PubMed ID: 15494423
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The pan-HDAC inhibitor vorinostat potentiates the activity of the proteasome inhibitor carfilzomib in human DLBCL cells in vitro and in vivo.
    Dasmahapatra G; Lembersky D; Kramer L; Fisher RI; Friedberg J; Dent P; Grant S
    Blood; 2010 Jun; 115(22):4478-87. PubMed ID: 20233973
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-kappaB-dependent process.
    Dai Y; Rahmani M; Grant S
    Oncogene; 2003 Oct; 22(46):7108-22. PubMed ID: 14562039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.
    Jin Y; Lu Z; Ding K; Li J; Du X; Chen C; Sun X; Wu Y; Zhou J; Pan J
    Cancer Res; 2010 Mar; 70(6):2516-27. PubMed ID: 20215516
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Carfilzomib interacts synergistically with histone deacetylase inhibitors in mantle cell lymphoma cells in vitro and in vivo.
    Dasmahapatra G; Lembersky D; Son MP; Attkisson E; Dent P; Fisher RI; Friedberg JW; Grant S
    Mol Cancer Ther; 2011 Sep; 10(9):1686-97. PubMed ID: 21750224
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppressed NF-kappaB and sustained JNK activation contribute to the sensitization effect of parthenolide to TNF-alpha-induced apoptosis in human cancer cells.
    Zhang S; Lin ZN; Yang CF; Shi X; Ong CN; Shen HM
    Carcinogenesis; 2004 Nov; 25(11):2191-9. PubMed ID: 15256485
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M; Reese E; Dai Y; Bauer C; Payne SG; Dent P; Spiegel S; Grant S
    Cancer Res; 2005 Mar; 65(6):2422-32. PubMed ID: 15781658
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01.
    Yeow WS; Ziauddin MF; Maxhimer JB; Shamimi-Noori S; Baras A; Chua A; Schrump DS; Nguyen DM
    Br J Cancer; 2006 May; 94(10):1436-45. PubMed ID: 16705314
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combined Parthenolide and Balsalazide Have Enhanced Antitumor Efficacy Through Blockade of NF-κB Activation.
    Kim SL; Kim SH; Park YR; Liu YC; Kim EM; Jeong HJ; Kim YN; Seo SY; Kim IH; Lee SO; Lee ST; Kim SW
    Mol Cancer Res; 2017 Feb; 15(2):141-151. PubMed ID: 28108625
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear factor-kappaB as a potential therapeutic target for the novel cytotoxic agent LC-1 in acute myeloid leukaemia.
    Jenkins C; Hewamana S; Gilkes A; Neelakantan S; Crooks P; Mills K; Pepper C; Burnett A
    Br J Haematol; 2008 Dec; 143(5):661-71. PubMed ID: 19036014
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The novel Chk1 inhibitor MK-8776 sensitizes human leukemia cells to HDAC inhibitors by targeting the intra-S checkpoint and DNA replication and repair.
    Dai Y; Chen S; Kmieciak M; Zhou L; Lin H; Pei XY; Grant S
    Mol Cancer Ther; 2013 Jun; 12(6):878-89. PubMed ID: 23536721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combined effects of FLT3 and NF-κB selective inhibitors on acute myeloid leukemia in vivo.
    Wang C; Lu J; Wang Y; Bai S; Wang Y; Wang L; Sheng G
    J Biochem Mol Toxicol; 2012 Jan; 26(1):35-43. PubMed ID: 21928377
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571.
    Yu C; Rahmani M; Conrad D; Subler M; Dent P; Grant S
    Blood; 2003 Nov; 102(10):3765-74. PubMed ID: 12893773
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.