BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 20709017)

  • 21. Characterization and crystal structure of lysine insensitive Corynebacterium glutamicum dihydrodipicolinate synthase (cDHDPS) protein.
    Rice EA; Bannon GA; Glenn KC; Jeong SS; Sturman EJ; Rydel TJ
    Arch Biochem Biophys; 2008 Dec; 480(2):111-21. PubMed ID: 18930704
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa.
    Kaur N; Gautam A; Kumar S; Singh A; Singh N; Sharma S; Sharma R; Tewari R; Singh TP
    Int J Biol Macromol; 2011 Jun; 48(5):779-87. PubMed ID: 21396954
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Exploring the allosteric mechanism of dihydrodipicolinate synthase by reverse engineering of the allosteric inhibitor binding sites and its application for lysine production.
    Geng F; Chen Z; Zheng P; Sun J; Zeng AP
    Appl Microbiol Biotechnol; 2013 Mar; 97(5):1963-71. PubMed ID: 22644522
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Exploring the dihydrodipicolinate synthase tetramer: how resilient is the dimer-dimer interface?
    Griffin MD; Dobson RC; Gerrard JA; Perugini MA
    Arch Biochem Biophys; 2010 Feb; 494(1):58-63. PubMed ID: 19919824
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Characterization of a thermostable dihydrodipicolinate synthase from Thermoanaerobacter tengcongensis.
    Wolterink-van Loo S; Levisson M; Cabrières MC; Franssen MC; van der Oost J
    Extremophiles; 2008 May; 12(3):461-9. PubMed ID: 18340401
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Dihydrodipicolinate synthase from Thermotoga maritima.
    Pearce FG; Perugini MA; McKerchar HJ; Gerrard JA
    Biochem J; 2006 Dec; 400(2):359-66. PubMed ID: 16872276
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Tyrosine 110 plays a critical role in regulating the allosteric inhibition of Campylobacter jejuni dihydrodipicolinate synthase by lysine.
    Conly CJ; Skovpen YV; Li S; Palmer DR; Sanders DA
    Biochemistry; 2014 Dec; 53(47):7396-406. PubMed ID: 25369463
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.
    Dobson RC; Griffin MD; Devenish SR; Pearce FG; Hutton CA; Gerrard JA; Jameson GB; Perugini MA
    Protein Sci; 2008 Dec; 17(12):2080-90. PubMed ID: 18787203
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Structural and functional characterization of Staphylococcus aureus dihydrodipicolinate synthase.
    Girish TS; Sharma E; Gopal B
    FEBS Lett; 2008 Aug; 582(19):2923-30. PubMed ID: 18671976
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.
    Domigan LJ; Scally SW; Fogg MJ; Hutton CA; Perugini MA; Dobson RC; Muscroft-Taylor AC; Gerrard JA; Devenish SR
    Biochim Biophys Acta; 2009 Oct; 1794(10):1510-6. PubMed ID: 19595801
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A rationally designed monomeric variant of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus is as active as the dimeric wild-type enzyme but less thermostable.
    Schwab T; Skegro D; Mayans O; Sterner R
    J Mol Biol; 2008 Feb; 376(2):506-16. PubMed ID: 18164726
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Structure of dihydrodipicolinate synthase from Methanocaldococcus jannaschii.
    Padmanabhan B; Strange RW; Antonyuk SV; Ellis MJ; Hasnain SS; Iino H; Agari Y; Bessho Y; Yokoyama S
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2009 Dec; 65(Pt 12):1222-6. PubMed ID: 20054116
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate.
    Turner JJ; Healy JP; Dobson RC; Gerrard JA; Hutton CA
    Bioorg Med Chem Lett; 2005 Feb; 15(4):995-8. PubMed ID: 15686899
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis.
    Sandmark J; Eliot AC; Famm K; Schneider G; Kirsch JF
    Biochemistry; 2004 Feb; 43(5):1213-22. PubMed ID: 14756557
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate.
    Devenish SR; Gerrard JA; Jameson GB; Dobson RC
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Dec; 64(Pt 12):1092-5. PubMed ID: 19052357
    [TBL] [Abstract][Full Text] [Related]  

  • 36. NMR studies uncover alternate substrates for dihydrodipicolinate synthase and suggest that dihydrodipicolinate reductase is also a dehydratase.
    Devenish SR; Blunt JW; Gerrard JA
    J Med Chem; 2010 Jun; 53(12):4808-12. PubMed ID: 20503968
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target.
    Soares da Costa TP; Desbois S; Dogovski C; Gorman MA; Ketaren NE; Paxman JJ; Siddiqui T; Zammit LM; Abbott BM; Robins-Browne RM; Parker MW; Jameson GB; Hall NE; Panjikar S; Perugini MA
    Structure; 2016 Aug; 24(8):1282-1291. PubMed ID: 27427481
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization.
    Pearce FG; Dobson RC; Jameson GB; Perugini MA; Gerrard JA
    Biochim Biophys Acta; 2011 Dec; 1814(12):1900-9. PubMed ID: 21803176
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis.
    Devenish SR; Huisman FH; Parker EJ; Hadfield AT; Gerrard JA
    Biochim Biophys Acta; 2009 Aug; 1794(8):1168-74. PubMed ID: 19236959
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde.
    Dobson RC; Gerrard JA; Pearce FG
    Biochem J; 2004 Feb; 377(Pt 3):757-62. PubMed ID: 14580236
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.