BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 20709644)

  • 1. Differential response to trichloroethylene-induced hepatosteatosis in wild-type and PPARalpha-humanized mice.
    Ramdhan DH; Kamijima M; Wang D; Ito Y; Naito H; Yanagiba Y; Hayashi Y; Tanaka N; Aoyama T; Gonzalez FJ; Nakajima T
    Environ Health Perspect; 2010 Nov; 118(11):1557-63. PubMed ID: 20709644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.
    Yoo HS; Cichocki JA; Kim S; Venkatratnam A; Iwata Y; Kosyk O; Bodnar W; Sweet S; Knap A; Wade T; Campbell J; Clewell HJ; Melnyk SB; Chiu WA; Rusyn I
    Toxicol Sci; 2015 Oct; 147(2):339-49. PubMed ID: 26136231
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatic peroxisome proliferator-activated receptor α may have an important role in the toxic effects of di(2-ethylhexyl)phthalate on offspring of mice.
    Hayashi Y; Ito Y; Yamagishi N; Yanagiba Y; Tamada H; Wang D; Ramdhan DH; Naito H; Harada Y; Kamijima M; Gonzales FJ; Nakajima T
    Toxicology; 2011 Oct; 289(1):1-10. PubMed ID: 21354252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of ammonium perfluorooctanoate-induced hepatic damage by genetically different PPARα in mice.
    Nakagawa T; Ramdhan DH; Tanaka N; Naito H; Tamada H; Ito Y; Li Y; Hayashi Y; Yamagishi N; Yanagiba Y; Aoyama T; Gonzalez FJ; Nakajima T
    Arch Toxicol; 2012 Jan; 86(1):63-74. PubMed ID: 21499893
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Microgram-order ammonium perfluorooctanoate may activate mouse peroxisome proliferator-activated receptor alpha, but not human PPARalpha.
    Nakamura T; Ito Y; Yanagiba Y; Ramdhan DH; Kono Y; Naito H; Hayashi Y; Li Y; Aoyama T; Gonzalez FJ; Nakajima T
    Toxicology; 2009 Nov; 265(1-2):27-33. PubMed ID: 19751795
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARα(PAC) mice due to dysregulated bile acid synthesis.
    Liu HX; Hu Y; French SW; Gonzalez FJ; Wan YJ
    Oncotarget; 2015; 6(12):9686-700. PubMed ID: 25991671
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of the peroxisome proliferator-activated receptor alpha (PPARalpha) in responses to trichloroethylene and metabolites, trichloroacetate and dichloroacetate in mouse liver.
    Laughter AR; Dunn CS; Swanson CL; Howroyd P; Cattley RC; Corton JC
    Toxicology; 2004 Oct; 203(1-3):83-98. PubMed ID: 15363585
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor alpha to Wy-14,643-induced liver tumorigenesis.
    Morimura K; Cheung C; Ward JM; Reddy JK; Gonzalez FJ
    Carcinogenesis; 2006 May; 27(5):1074-80. PubMed ID: 16377806
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perfluoroalkyl acids-induced liver steatosis: Effects on genes controlling lipid homeostasis.
    Das KP; Wood CR; Lin MT; Starkov AA; Lau C; Wallace KB; Corton JC; Abbott BD
    Toxicology; 2017 Mar; 378():37-52. PubMed ID: 28049043
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1.
    Ramdhan DH; Kamijima M; Yamada N; Ito Y; Yanagiba Y; Nakamura D; Okamura A; Ichihara G; Aoyama T; Gonzalez FJ; Nakajima T
    Toxicol Appl Pharmacol; 2008 Sep; 231(3):300-7. PubMed ID: 18565563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PPARα protects against trans-fatty-acid-containing diet-induced steatohepatitis.
    Hu X; Tanaka N; Guo R; Lu Y; Nakajima T; Gonzalez FJ; Aoyama T
    J Nutr Biochem; 2017 Jan; 39():77-85. PubMed ID: 27816763
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transgenic expression of mutant peroxisome proliferator-activated receptor gamma in liver precipitates fasting-induced steatosis but protects against high-fat diet-induced steatosis in mice.
    Tanaka T; Masuzaki H; Ebihara K; Ogawa Y; Yasue S; Yukioka H; Chusho H; Miyanaga F; Miyazawa T; Fujimoto M; Kusakabe T; Kobayashi N; Hayashi T; Hosoda K; Nakao K
    Metabolism; 2005 Nov; 54(11):1490-8. PubMed ID: 16253638
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPARα mice fed an American diet.
    Schlezinger JJ; Hyötyläinen T; Sinioja T; Boston C; Puckett H; Oliver J; Heiger-Bernays W; Webster TF
    Toxicol Appl Pharmacol; 2021 Sep; 426():115644. PubMed ID: 34252412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Perfluorooctanoic acid activates multiple nuclear receptor pathways and skews expression of genes regulating cholesterol homeostasis in liver of humanized PPARα mice fed an American diet.
    Schlezinger JJ; Puckett H; Oliver J; Nielsen G; Heiger-Bernays W; Webster TF
    Toxicol Appl Pharmacol; 2020 Oct; 405():115204. PubMed ID: 32822737
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ammonium perfluorooctanoate may cause testosterone reduction by adversely affecting testis in relation to PPARα.
    Li Y; Ramdhan DH; Naito H; Yamagishi N; Ito Y; Hayashi Y; Yanagiba Y; Okamura A; Tamada H; Gonzalez FJ; Nakajima T
    Toxicol Lett; 2011 Sep; 205(3):265-72. PubMed ID: 21712084
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Divergence between human and murine peroxisome proliferator-activated receptor alpha ligand specificities.
    Oswal DP; Balanarasimha M; Loyer JK; Bedi S; Soman FL; Rider SD; Hostetler HA
    J Lipid Res; 2013 Sep; 54(9):2354-65. PubMed ID: 23797899
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Importance of PPAR alpha for the effects of growth hormone on hepatic lipid and lipoprotein metabolism.
    Ljungberg A; Lindén D; Améen C; Bergström G; Oscarsson J
    Growth Horm IGF Res; 2007 Apr; 17(2):154-64. PubMed ID: 17307376
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Glucocorticoid Receptor β Induces Hepatic Steatosis by Augmenting Inflammation and Inhibition of the Peroxisome Proliferator-activated Receptor (PPAR) α.
    Marino JS; Stechschulte LA; Stec DE; Nestor-Kalinoski A; Coleman S; Hinds TD
    J Biol Chem; 2016 Dec; 291(50):25776-25788. PubMed ID: 27784782
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Di(2-ethylhexyl)phthalate induces hepatic tumorigenesis through a peroxisome proliferator-activated receptor alpha-independent pathway.
    Ito Y; Yamanoshita O; Asaeda N; Tagawa Y; Lee CH; Aoyama T; Ichihara G; Furuhashi K; Kamijima M; Gonzalez FJ; Nakajima T
    J Occup Health; 2007 May; 49(3):172-82. PubMed ID: 17575397
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
    McCarthy TC; Pollak PT; Hanniman EA; Sinal CJ
    J Pharmacol Exp Ther; 2004 Dec; 311(3):864-73. PubMed ID: 15265979
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.