341 related articles for article (PubMed ID: 20709748)
1. Splice variants of SmgGDS control small GTPase prenylation and membrane localization.
Berg TJ; Gastonguay AJ; Lorimer EL; Kuhnmuench JR; Li R; Fields AP; Williams CL
J Biol Chem; 2010 Nov; 285(46):35255-66. PubMed ID: 20709748
[TBL] [Abstract][Full Text] [Related]
2. The chaperone protein SmgGDS interacts with small GTPases entering the prenylation pathway by recognizing the last amino acid in the CAAX motif.
Schuld NJ; Vervacke JS; Lorimer EL; Simon NC; Hauser AD; Barbieri JT; Distefano MD; Williams CL
J Biol Chem; 2014 Mar; 289(10):6862-6876. PubMed ID: 24415755
[TBL] [Abstract][Full Text] [Related]
3. Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy.
Brandt AC; McNally L; Lorimer EL; Unger B; Koehn OJ; Suazo KF; Rein L; Szabo A; Tsaih SW; Distefano MD; Flister MJ; Rigo F; McNally MT; Williams CL
Proc Natl Acad Sci U S A; 2020 Feb; 117(7):3627-3636. PubMed ID: 32019878
[TBL] [Abstract][Full Text] [Related]
4. Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B.
Wilson JM; Prokop JW; Lorimer E; Ntantie E; Williams CL
J Mol Biol; 2016 Dec; 428(24 Pt B):4929-4945. PubMed ID: 27760305
[TBL] [Abstract][Full Text] [Related]
5. The chaperone SmgGDS-607 has a dual role, both activating and inhibiting farnesylation of small GTPases.
García-Torres D; Fierke CA
J Biol Chem; 2019 Aug; 294(31):11793-11804. PubMed ID: 31197034
[TBL] [Abstract][Full Text] [Related]
6. SmgGDS-607 Regulation of RhoA GTPase Prenylation Is Nucleotide-Dependent.
Jennings BC; Lawton AJ; Rizk Z; Fierke CA
Biochemistry; 2018 Jul; 57(29):4289-4298. PubMed ID: 29940100
[TBL] [Abstract][Full Text] [Related]
7. GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS.
Koehn OJ; Lorimer E; Unger B; Harris R; Das AS; Suazo KF; Auger SA; Distefano MD; Prokop JW; Williams CL
J Biol Chem; 2023 Jun; 299(6):104698. PubMed ID: 37059183
[TBL] [Abstract][Full Text] [Related]
8. The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences.
Williams CL
Cell Signal; 2003 Dec; 15(12):1071-80. PubMed ID: 14575862
[TBL] [Abstract][Full Text] [Related]
9. SmgGDS displays differential binding and exchange activity towards different Ras isoforms.
Vikis HG; Stewart S; Guan KL
Oncogene; 2002 Apr; 21(15):2425-32. PubMed ID: 11948427
[TBL] [Abstract][Full Text] [Related]
10. Structure-based analysis of the guanine nucleotide exchange factor SmgGDS reveals armadillo-repeat motifs and key regions for activity and GTPase binding.
Shimizu H; Toma-Fukai S; Saijo S; Shimizu N; Kontani K; Katada T; Shimizu T
J Biol Chem; 2017 Aug; 292(32):13441-13448. PubMed ID: 28630045
[TBL] [Abstract][Full Text] [Related]
11. The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases.
Bergom C; Hauser AD; Rymaszewski A; Gonyo P; Prokop JW; Jennings BC; Lawton AJ; Frei A; Lorimer EL; Aguilera-Barrantes I; Mackinnon AC; Noon K; Fierke CA; Williams CL
J Biol Chem; 2016 Mar; 291(12):6534-45. PubMed ID: 26814130
[TBL] [Abstract][Full Text] [Related]
12. SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers.
Schuld NJ; Hauser AD; Gastonguay AJ; Wilson JM; Lorimer EL; Williams CL
Cell Cycle; 2014; 13(6):941-52. PubMed ID: 24552806
[TBL] [Abstract][Full Text] [Related]
13. SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.
Hamel B; Monaghan-Benson E; Rojas RJ; Temple BR; Marston DJ; Burridge K; Sondek J
J Biol Chem; 2011 Apr; 286(14):12141-8. PubMed ID: 21242305
[TBL] [Abstract][Full Text] [Related]
14. Structural and biophysical properties of farnesylated KRas interacting with the chaperone SmgGDS-558.
Michalak DJ; Unger B; Lorimer E; Grishaev A; Williams CL; Heinrich F; Lösche M
Biophys J; 2022 Oct; 121(19):3684-3697. PubMed ID: 35614853
[TBL] [Abstract][Full Text] [Related]
15. SmgGDS: An Emerging Master Regulator of Prenylation and Trafficking by Small GTPases in the Ras and Rho Families.
Brandt AC; Koehn OJ; Williams CL
Front Mol Biosci; 2021; 8():685135. PubMed ID: 34222337
[TBL] [Abstract][Full Text] [Related]
16. GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
Shimizu H; Toma-Fukai S; Kontani K; Katada T; Shimizu T
Proc Natl Acad Sci U S A; 2018 Sep; 115(38):9563-9568. PubMed ID: 30190425
[TBL] [Abstract][Full Text] [Related]
17. Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.
Lanning CC; Ruiz-Velasco R; Williams CL
J Biol Chem; 2003 Apr; 278(14):12495-506. PubMed ID: 12551911
[TBL] [Abstract][Full Text] [Related]
18. Unique in vivo associations with SmgGDS and RhoGDI and different guanine nucleotide exchange activities exhibited by RhoA, dominant negative RhoA(Asn-19), and activated RhoA(Val-14).
Strassheim D; Porter RA; Phelps SH; Williams CL
J Biol Chem; 2000 Mar; 275(10):6699-702. PubMed ID: 10702222
[TBL] [Abstract][Full Text] [Related]
19. SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism.
Chuang TH; Xu X; Quilliam LA; Bokoch GM
Biochem J; 1994 Nov; 303 ( Pt 3)(Pt 3):761-7. PubMed ID: 7980444
[TBL] [Abstract][Full Text] [Related]
20. The SmgGDS splice variant SmgGDS-558 is a key promoter of tumor growth and RhoA signaling in breast cancer.
Hauser AD; Bergom C; Schuld NJ; Chen X; Lorimer EL; Huang J; Mackinnon AC; Williams CL
Mol Cancer Res; 2014 Jan; 12(1):130-42. PubMed ID: 24197117
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]