233 related articles for article (PubMed ID: 20715795)
1. Double duty for a conserved glutamate in pyruvate decarboxylase: evidence of the participation in stereoelectronically controlled decarboxylation and in protonation of the nascent carbanion/enamine intermediate .
Meyer D; Neumann P; Parthier C; Friedemann R; Nemeria N; Jordan F; Tittmann K
Biochemistry; 2010 Sep; 49(37):8197-212. PubMed ID: 20715795
[TBL] [Abstract][Full Text] [Related]
2. Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.
Schütz A; Golbik R; König S; Hübner G; Tittmann K
Biochemistry; 2005 Apr; 44(16):6164-79. PubMed ID: 15835904
[TBL] [Abstract][Full Text] [Related]
3. Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
Chakraborty S; Nemeria NS; Balakrishnan A; Brandt GS; Kneen MM; Yep A; McLeish MJ; Kenyon GL; Petsko GA; Ringe D; Jordan F
Biochemistry; 2009 Feb; 48(5):981-94. PubMed ID: 19140682
[TBL] [Abstract][Full Text] [Related]
4. Structural and kinetic studies on native intermediates and an intermediate analogue in benzoylformate decarboxylase reveal a least motion mechanism with an unprecedented short-lived predecarboxylation intermediate.
Bruning M; Berheide M; Meyer D; Golbik R; Bartunik H; Liese A; Tittmann K
Biochemistry; 2009 Apr; 48(15):3258-68. PubMed ID: 19182954
[TBL] [Abstract][Full Text] [Related]
5. Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.
Balakrishnan A; Gao Y; Moorjani P; Nemeria NS; Tittmann K; Jordan F
J Am Chem Soc; 2012 Feb; 134(8):3873-85. PubMed ID: 22300533
[TBL] [Abstract][Full Text] [Related]
6. Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4'-aminopyrimidinium and 1',4'-iminopyrimidine tautomeric forms in the absence of the conserved glutamate.
Nemeria N; Binshtein E; Patel H; Balakrishnan A; Vered I; Shaanan B; Barak Z; Chipman D; Jordan F
Biochemistry; 2012 Oct; 51(40):7940-52. PubMed ID: 22970650
[TBL] [Abstract][Full Text] [Related]
7. Radical phosphate transfer mechanism for the thiamin diphosphate- and FAD-dependent pyruvate oxidase from Lactobacillus plantarum. Kinetic coupling of intercofactor electron transfer with phosphate transfer to acetyl-thiamin diphosphate via a transient FAD semiquinone/hydroxyethyl-ThDP radical pair.
Tittmann K; Wille G; Golbik R; Weidner A; Ghisla S; Hübner G
Biochemistry; 2005 Oct; 44(40):13291-303. PubMed ID: 16201755
[TBL] [Abstract][Full Text] [Related]
8. Tetrahedral intermediates in thiamin diphosphate-dependent decarboxylations exist as a 1',4'-imino tautomeric form of the coenzyme, unlike the michaelis complex or the free coenzyme.
Nemeria N; Baykal A; Joseph E; Zhang S; Yan Y; Furey W; Jordan F
Biochemistry; 2004 Jun; 43(21):6565-75. PubMed ID: 15157089
[TBL] [Abstract][Full Text] [Related]
9. The role of residues glutamate-50 and phenylalanine-496 in Zymomonas mobilis pyruvate decarboxylase.
Candy JM; Koga J; Nixon PF; Duggleby RG
Biochem J; 1996 May; 315 ( Pt 3)(Pt 3):745-51. PubMed ID: 8645153
[TBL] [Abstract][Full Text] [Related]
10. Theoretical Studies of the Electronic Absorption Spectra of Thiamin Diphosphate in Pyruvate Decarboxylase.
Paulikat M; Wechsler C; Tittmann K; Mata RA
Biochemistry; 2017 Apr; 56(13):1854-1864. PubMed ID: 28296385
[TBL] [Abstract][Full Text] [Related]
11. Oxidative decarboxylation of pyruvate by 1-deoxy-d-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria.
DeColli AA; Nemeria NS; Majumdar A; Gerfen GJ; Jordan F; Freel Meyers CL
J Biol Chem; 2018 Jul; 293(28):10857-10869. PubMed ID: 29784878
[TBL] [Abstract][Full Text] [Related]
12. Progress in the experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observations.
Jordan F; Nemeria NS
Bioorg Chem; 2014 Dec; 57():251-262. PubMed ID: 25228115
[TBL] [Abstract][Full Text] [Related]
13. Investigation of the cofactor-binding site of Zymomonas mobilis pyruvate decarboxylase by site-directed mutagenesis.
Candy JM; Duggleby RG
Biochem J; 1994 May; 300 ( Pt 1)(Pt 1):7-13. PubMed ID: 8198554
[TBL] [Abstract][Full Text] [Related]
14. Mutagenesis at asp27 of pyruvate decarboxylase from Zymomonas mobilis. Effect on its ability to form acetoin and acetolactate.
Wu YG; Chang AK; Nixon PF; Li W; Duggleby RG
Eur J Biochem; 2000 Nov; 267(21):6493-500. PubMed ID: 11029594
[TBL] [Abstract][Full Text] [Related]
15. Experimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observations.
Jordan F; Nemeria NS
Bioorg Chem; 2005 Jun; 33(3):190-215. PubMed ID: 15888311
[TBL] [Abstract][Full Text] [Related]
16. The catalytic cycle of a thiamin diphosphate enzyme examined by cryocrystallography.
Wille G; Meyer D; Steinmetz A; Hinze E; Golbik R; Tittmann K
Nat Chem Biol; 2006 Jun; 2(6):324-8. PubMed ID: 16680160
[TBL] [Abstract][Full Text] [Related]
17. Observation of thiamin-bound intermediates and microscopic rate constants for their interconversion on 1-deoxy-D-xylulose 5-phosphate synthase: 600-fold rate acceleration of pyruvate decarboxylation by D-glyceraldehyde-3-phosphate.
Patel H; Nemeria NS; Brammer LA; Freel Meyers CL; Jordan F
J Am Chem Soc; 2012 Nov; 134(44):18374-9. PubMed ID: 23072514
[TBL] [Abstract][Full Text] [Related]
18. Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase.
Polovnikova ES; McLeish MJ; Sergienko EA; Burgner JT; Anderson NL; Bera AK; Jordan F; Kenyon GL; Hasson MS
Biochemistry; 2003 Feb; 42(7):1820-30. PubMed ID: 12590569
[TBL] [Abstract][Full Text] [Related]
19. Cofactor activation and substrate binding in pyruvate decarboxylase. Insights into the reaction mechanism from molecular dynamics simulations.
Lie MA; Celik L; Jørgensen KA; Schiøtt B
Biochemistry; 2005 Nov; 44(45):14792-806. PubMed ID: 16274227
[TBL] [Abstract][Full Text] [Related]
20. The role of His113 and His114 in pyruvate decarboxylase from Zymomonas mobilis.
Schenk G; Leeper FJ; England R; Nixon PF; Duggleby RG
Eur J Biochem; 1997 Aug; 248(1):63-71. PubMed ID: 9310361
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
