BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 20717119)

  • 21. 3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.
    Ferrins L; Rahmani R; Sykes ML; Jones AJ; Avery VM; Teston E; Almohaywi B; Yin J; Smith J; Hyland C; White KL; Ryan E; Campbell M; Charman SA; Kaiser M; Baell JB
    Eur J Med Chem; 2013 Aug; 66():450-65. PubMed ID: 23831695
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Bistacrines as potential antitrypanosomal agents.
    Schmidt I; Göllner S; Fuß A; Stich A; Kucharski A; Schirmeister T; Katzowitsch E; Bruhn H; Miliu A; Krauth-Siegel RL; Holzgrabe U
    Bioorg Med Chem; 2017 Aug; 25(16):4526-4531. PubMed ID: 28698054
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Identification of novel inhibitors of UDP-Glc 4'-epimerase, a validated drug target for african sleeping sickness.
    Urbaniak MD; Tabudravu JN; Msaki A; Matera KM; Brenk R; Jaspars M; Ferguson MA
    Bioorg Med Chem Lett; 2006 Nov; 16(22):5744-7. PubMed ID: 16962325
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Evaluation of medicinal plants from Mali for their in vitro and in vivo trypanocidal activity.
    Bizimana N; Tietjen U; Zessin KH; Diallo D; Djibril C; Melzig MF; Clausen PH
    J Ethnopharmacol; 2006 Feb; 103(3):350-6. PubMed ID: 16188409
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Brain-Penetrant Triazolopyrimidine and Phenylpyrimidine Microtubule Stabilizers as Potential Leads to Treat Human African Trypanosomiasis.
    Monti L; Wang SC; Oukoloff K; Smith AB; Brunden KR; Caffrey CR; Ballatore C
    ChemMedChem; 2018 Sep; 13(17):1751-1754. PubMed ID: 29969537
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Antitrypanosomal naphthylisoquinoline alkaloids and related compounds.
    Bringmann G; Hoerr V; Holzgrabe U; Stich A
    Pharmazie; 2003 May; 58(5):343-6. PubMed ID: 12779053
    [TBL] [Abstract][Full Text] [Related]  

  • 27. In vitro antitrypanosomal activity of the cyclodepsipeptides, cardinalisamides A-C, from the insect pathogenic fungus Cordyceps cardinalis NBRC 103832.
    Umeyama A; Takahashi K; Grudniewska A; Shimizu M; Hayashi S; Kato M; Okamoto Y; Suenaga M; Ban S; Kumada T; Ishiyama A; Iwatsuki M; Otoguro K; Omura S; Hashimoto T
    J Antibiot (Tokyo); 2014 Feb; 67(2):163-6. PubMed ID: 24084682
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Contribution of N,N'-dialkylbenzamide groups to trypanocidal properties of spiroarsoranes.
    Loiseau PM; Bories C; Trabelsi M; Gayral P; Wolf JG
    Parasitol Res; 1994; 80(8):708-10. PubMed ID: 7886045
    [No Abstract]   [Full Text] [Related]  

  • 29. Spiroarsoranes of second generation: evaluation of trypanocidal properties against Trypanosoma brucei brucei.
    Loiseau PM; Wolf JG; Gayral P
    Trop Med Parasitol; 1993 Mar; 44(1):32-6. PubMed ID: 8516630
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Antitrypanosomal structure-activity-relationship study of synthetic cynaropicrin derivatives.
    Usuki T; Sato M; Hara S; Yoshimoto Y; Kondo R; Zimmermann S; Kaiser M; Brun R; Hamburger M; Adams M
    Bioorg Med Chem Lett; 2014 Feb; 24(3):794-8. PubMed ID: 24433861
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The effect of TAO expression on PCD-like phenomenon development and drug resistance in Trypanosoma brucei.
    Tsuda A; Witola WH; Konnai S; Ohashi K; Onuma M
    Parasitol Int; 2006 Jun; 55(2):135-42. PubMed ID: 16516538
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent.
    Yang PY; Wang M; Liu K; Ngai MH; Sheriff O; Lear MJ; Sze SK; He CY; Yao SQ
    Chemistry; 2012 Jul; 18(27):8403-13. PubMed ID: 22674877
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.
    Vodnala SK; Lundbäck T; Yeheskieli E; Sjöberg B; Gustavsson AL; Svensson R; Olivera GC; Eze AA; de Koning HP; Hammarström LG; Rottenberg ME
    J Med Chem; 2013 Dec; 56(24):9861-73. PubMed ID: 24283924
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and evaluation of analogs of the phenylpyridazinone NPD-001 as potent trypanosomal TbrPDEB1 phosphodiesterase inhibitors and in vitro trypanocidals.
    Veerman J; van den Bergh T; Orrling KM; Jansen C; Cos P; Maes L; Chatelain E; Ioset JR; Edink EE; Tenor H; Seebeck T; de Esch I; Leurs R; Sterk GJ
    Bioorg Med Chem; 2016 Apr; 24(7):1573-81. PubMed ID: 26935942
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis.
    Klug DM; Mavrogiannaki EM; Forbes KC; Silva L; Diaz-Gonzalez R; Pérez-Moreno G; Ceballos-Pérez G; Garcia-Hernández R; Bosch-Navarrete C; Cordón-Obras C; Gómez-Liñán C; Saura A; Momper JD; Martinez-Martinez MS; Manzano P; Syed A; El-Sakkary N; Caffrey CR; Gamarro F; Ruiz-Perez LM; Gonzalez Pacanowska D; Ferrins L; Navarro M; Pollastri MP
    J Med Chem; 2021 Jul; 64(13):9404-9430. PubMed ID: 34156862
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Anti-trypanosomal activity of doubly modified salinomycin derivatives.
    Antoszczak M; Steverding D; Sulik M; Janczak J; Huczyński A
    Eur J Med Chem; 2019 Jul; 173():90-98. PubMed ID: 30986574
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei.
    Mackey ZB; Baca AM; Mallari JP; Apsel B; Shelat A; Hansell EJ; Chiang PK; Wolff B; Guy KR; Williams J; McKerrow JH
    Chem Biol Drug Des; 2006 May; 67(5):355-63. PubMed ID: 16784460
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Parasitology. Drugs to combat tropical protozoan parasites.
    Gelb MH; Hol WG
    Science; 2002 Jul; 297(5580):343-4. PubMed ID: 12130767
    [No Abstract]   [Full Text] [Related]  

  • 39. In vitro activity of the trypanocidal diamidine DAPI on animal-infective Trypanosoma brucei brucei.
    Borowy NK; Fink E; Hirumi H
    Acta Trop; 1985 Dec; 42(4):287-98. PubMed ID: 2868631
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Identification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis.
    Jones AJ; Kaiser M; Avery VM
    Antimicrob Agents Chemother; 2015 Dec; 60(3):1859-61. PubMed ID: 26666915
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.