BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

468 related articles for article (PubMed ID: 20723758)

  • 1. Structural basis for negative cooperativity in growth factor binding to an EGF receptor.
    Alvarado D; Klein DE; Lemmon MA
    Cell; 2010 Aug; 142(4):568-79. PubMed ID: 20723758
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis for EGFR ligand sequestration by Argos.
    Klein DE; Stayrook SE; Shi F; Narayan K; Lemmon MA
    Nature; 2008 Jun; 453(7199):1271-5. PubMed ID: 18500331
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding.
    Adak S; Yang KS; Macdonald-Obermann J; Pike LJ
    J Biol Chem; 2011 Dec; 286(52):45146-55. PubMed ID: 22069315
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A single ligand is sufficient to activate EGFR dimers.
    Liu P; Cleveland TE; Bouyain S; Byrne PO; Longo PA; Leahy DJ
    Proc Natl Acad Sci U S A; 2012 Jul; 109(27):10861-6. PubMed ID: 22699492
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The extracellular domain of the epidermal growth factor receptor. Studies on the affinity and stoichiometry of binding, receptor dimerization and a binding-domain mutant.
    Brown PM; Debanne MT; Grothe S; Bergsma D; Caron M; Kay C; O'Connor-McCourt MD
    Eur J Biochem; 1994 Oct; 225(1):223-33. PubMed ID: 7925442
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ligand regulation of a constitutively dimeric EGF receptor.
    Freed DM; Alvarado D; Lemmon MA
    Nat Commun; 2015 Jun; 6():7380. PubMed ID: 26060020
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular determinants of epidermal growth factor binding: a molecular dynamics study.
    Sanders JM; Wampole ME; Thakur ML; Wickstrom E
    PLoS One; 2013; 8(1):e54136. PubMed ID: 23382875
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding.
    Macdonald-Obermann JL; Pike LJ
    J Biol Chem; 2009 May; 284(20):13570-13576. PubMed ID: 19336395
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of the catalytic activity of the EGF receptor.
    Endres NF; Engel K; Das R; Kovacs E; Kuriyan J
    Curr Opin Struct Biol; 2011 Dec; 21(6):777-84. PubMed ID: 21868214
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ligand-binding enhances the affinity of dimerization of the extracellular domain of the epidermal growth factor receptor.
    Odaka M; Kohda D; Lax I; Schlessinger J; Inagaki F
    J Biochem; 1997 Jul; 122(1):116-21. PubMed ID: 9276679
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains.
    Ogiso H; Ishitani R; Nureki O; Fukai S; Yamanaka M; Kim JH; Saito K; Sakamoto A; Inoue M; Shirouzu M; Yokoyama S
    Cell; 2002 Sep; 110(6):775-87. PubMed ID: 12297050
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Membrane interaction of bound ligands contributes to the negative binding cooperativity of the EGF receptor.
    Arkhipov A; Shan Y; Kim ET; Shaw DE
    PLoS Comput Biol; 2014 Jul; 10(7):e1003742. PubMed ID: 25058506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Real-time measurements of kinetics of EGF binding to soluble EGF receptor monomers and dimers support the dimerization model for receptor activation.
    Zhou M; Felder S; Rubinstein M; Hurwitz DR; Ullrich A; Lax I; Schlessinger J
    Biochemistry; 1993 Aug; 32(32):8193-8. PubMed ID: 8347619
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor.
    Alvarado D; Klein DE; Lemmon MA
    Nature; 2009 Sep; 461(7261):287-91. PubMed ID: 19718021
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human epidermal growth factor receptor (EGFR) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry.
    Tynan CJ; Roberts SK; Rolfe DJ; Clarke DT; Loeffler HH; Kästner J; Winn MD; Parker PJ; Martin-Fernandez ML
    Mol Cell Biol; 2011 Jun; 31(11):2241-52. PubMed ID: 21444717
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Implications of epidermal growth factor (EGF) induced egf receptor aggregation.
    Wofsy C; Goldstein B; Lund K; Wiley HS
    Biophys J; 1992 Jul; 63(1):98-110. PubMed ID: 1420877
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Negative co-operativity in the EGF receptor.
    Pike LJ
    Biochem Soc Trans; 2012 Feb; 40(1):15-9. PubMed ID: 22260659
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.
    Walker F; Orchard SG; Jorissen RN; Hall NE; Zhang HH; Hoyne PA; Adams TE; Johns TG; Ward C; Garrett TP; Zhu HJ; Nerrie M; Scott AM; Nice EC; Burgess AW
    J Biol Chem; 2004 May; 279(21):22387-98. PubMed ID: 15016810
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization.
    Ferguson KM; Berger MB; Mendrola JM; Cho HS; Leahy DJ; Lemmon MA
    Mol Cell; 2003 Feb; 11(2):507-17. PubMed ID: 12620237
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent.
    Gill K; Macdonald-Obermann JL; Pike LJ
    J Biol Chem; 2017 Dec; 292(50):20744-20755. PubMed ID: 29074618
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.