These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 20724150)

  • 1. Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: optimization of in vitro activity.
    Peters JU; Kühne H; Dehmlow H; Grether U; Conte A; Hainzl D; Hertel C; Kratochwil NA; Otteneder M; Narquizian R; Panousis CG; Ricklin F; Röver S
    Bioorg Med Chem Lett; 2010 Sep; 20(18):5426-30. PubMed ID: 20724150
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analogues of acifran: agonists of the high and low affinity niacin receptors, GPR109a and GPR109b.
    Jung JK; Johnson BR; Duong T; Decaire M; Uy J; Gharbaoui T; Boatman PD; Sage CR; Chen R; Richman JG; Connolly DT; Semple G
    J Med Chem; 2007 Apr; 50(7):1445-8. PubMed ID: 17358052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74.
    Mahboubi K; Witman-Jones T; Adamus JE; Letsinger JT; Whitehouse D; Moorman AR; Sawicki D; Bergenhem N; Ross SA
    Biochem Biophys Res Commun; 2006 Feb; 340(2):482-90. PubMed ID: 16389067
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b.
    Skinner PJ; Cherrier MC; Webb PJ; Sage CR; Dang HT; Pride CC; Chen R; Tamura SY; Richman JG; Connolly DT; Semple G
    Bioorg Med Chem Lett; 2007 Dec; 17(23):6619-22. PubMed ID: 17931863
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fluorinated pyrazole acids are agonists of the high affinity niacin receptor GPR109a.
    Skinner PJ; Cherrier MC; Webb PJ; Shin YJ; Gharbaoui T; Lindstrom A; Hong V; Tamura SY; Dang HT; Pride CC; Chen R; Richman JG; Connolly DT; Semple G
    Bioorg Med Chem Lett; 2007 Oct; 17(20):5620-3. PubMed ID: 17804224
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 1-Alkyl-benzotriazole-5-carboxylic acids are highly selective agonists of the human orphan G-protein-coupled receptor GPR109b.
    Semple G; Skinner PJ; Cherrier MC; Webb PJ; Sage CR; Tamura SY; Chen R; Richman JG; Connolly DT
    J Med Chem; 2006 Feb; 49(4):1227-30. PubMed ID: 16480258
    [TBL] [Abstract][Full Text] [Related]  

  • 7. GPR109a agonists. Part 2: pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a.
    Imbriglio JE; Chang S; Liang R; Raghavan S; Schmidt D; Smenton A; Tria S; Schrader TO; Jung JK; Esser C; Holt TG; Wolff MS; Taggart AK; Cheng K; Carballo-Jane E; Waters MG; Tata JR; Colletti SL
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4472-4. PubMed ID: 20615702
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evidence for constitutive dimerization of niacin receptor subtypes.
    Mandrika I; Petrovska R; Klovins J
    Biochem Biophys Res Commun; 2010 Apr; 395(2):281-7. PubMed ID: 20380810
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of determinants of ligand binding to the nicotinic acid receptor GPR109A (HM74A/PUMA-G).
    Tunaru S; Lättig J; Kero J; Krause G; Offermanns S
    Mol Pharmacol; 2005 Nov; 68(5):1271-80. PubMed ID: 16099840
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Variations in human HM74 (GPR109B) and HM74A (GPR109A) niacin receptors.
    Zellner C; Pullinger CR; Aouizerat BE; Frost PH; Kwok PY; Malloy MJ; Kane JP
    Hum Mutat; 2005 Jan; 25(1):18-21. PubMed ID: 15580557
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor.
    Shen HC; Ding FX; Luell S; Forrest MJ; Carballo-Jane E; Wu KK; Wu TJ; Cheng K; Wilsie LC; Krsmanovic ML; Taggart AK; Ren N; Cai TQ; Deng Q; Chen Q; Wang J; Wolff MS; Tong X; Holt TG; Waters MG; Hammond ML; Tata JR; Colletti SL
    J Med Chem; 2007 Dec; 50(25):6303-6. PubMed ID: 17994679
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b.
    Skinner PJ; Webb PJ; Sage CR; Dang TH; Pride CC; Chen R; Tamura SY; Richman JG; Connolly DT; Semple G
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4207-9. PubMed ID: 19524438
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular modeling aided design of nicotinic acid receptor GPR109A agonists.
    Deng Q; Frie JL; Marley DM; Beresis RT; Ren N; Cai TQ; Taggart AK; Cheng K; Carballo-Jane E; Wang J; Tong X; Waters MG; Tata JR; Colletti SL
    Bioorg Med Chem Lett; 2008 Sep; 18(18):4963-7. PubMed ID: 18760600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A.
    Shen HC; Taggart AK; Wilsie LC; Waters MG; Hammond ML; Tata JR; Colletti SL
    Bioorg Med Chem Lett; 2008 Sep; 18(18):4948-51. PubMed ID: 18752940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109A.
    Shen HC; Szymonifka MJ; Kharbanda D; Deng Q; Carballo-Jane E; Wu KK; Wu TJ; Cheng K; Ren N; Cai TQ; Taggart AK; Wang J; Tong X; Waters MG; Hammond ML; Tata JR; Colletti SL
    Bioorg Med Chem Lett; 2007 Dec; 17(24):6723-8. PubMed ID: 18029181
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of pyrazolyl propionyl cyclohexenamide derivatives as full agonists for the high affinity niacin receptor GPR109A.
    Ding FX; Shen HC; Wilsie LC; Krsmanovic ML; Taggart AK; Ren N; Cai TQ; Wang J; Tong X; Holt TG; Chen Q; Waters MG; Hammond ML; Tata JR; Colletti SL
    Bioorg Med Chem Lett; 2010 Jun; 20(11):3372-5. PubMed ID: 20452209
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a).
    Boatman PD; Schrader TO; Kasem M; Johnson BR; Skinner PJ; Jung JK; Xu J; Cherrier MC; Webb PJ; Semple G; Sage CR; Knudsen J; Chen R; Taggart AK; Carballo-Jane E; Richman JG
    Bioorg Med Chem Lett; 2010 May; 20(9):2797-800. PubMed ID: 20363624
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nicotinic acid (niacin) receptor agonists: will they be useful therapeutic agents?
    Kamanna VS; Kashyap ML
    Am J Cardiol; 2007 Dec; 100(11 A):S53-61. PubMed ID: 18047854
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A.
    Zhang Y; Schmidt RJ; Foxworthy P; Emkey R; Oler JK; Large TH; Wang H; Su EW; Mosior MK; Eacho PI; Cao G
    Biochem Biophys Res Commun; 2005 Aug; 334(2):729-32. PubMed ID: 16018973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The high-affinity niacin receptor HM74A is decreased in the anterior cingulate cortex of individuals with schizophrenia.
    Miller CL; Dulay JR
    Brain Res Bull; 2008 Sep; 77(1):33-41. PubMed ID: 18639743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.