BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 20725905)

  • 1. The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation.
    Lai JP; Oseini AM; Moser CD; Yu C; Elsawa SF; Hu C; Nakamura I; Han T; Aderca I; Isomoto H; Garrity-Park MM; Shire AM; Li J; Sanderson SO; Adjei AA; Fernandez-Zapico ME; Roberts LR
    Hepatology; 2010 Nov; 52(5):1680-9. PubMed ID: 20725905
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma.
    Lai JP; Sandhu DS; Yu C; Han T; Moser CD; Jackson KK; Guerrero RB; Aderca I; Isomoto H; Garrity-Park MM; Zou H; Shire AM; Nagorney DM; Sanderson SO; Adjei AA; Lee JS; Thorgeirsson SS; Roberts LR
    Hepatology; 2008 Apr; 47(4):1211-22. PubMed ID: 18318435
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sulfatase 2 protects hepatocellular carcinoma cells against apoptosis induced by the PI3K inhibitor LY294002 and ERK and JNK kinase inhibitors.
    Lai JP; Sandhu DS; Yu C; Moser CD; Hu C; Shire AM; Aderca I; Murphy LM; Adjei AA; Sanderson S; Roberts LR
    Liver Int; 2010 Nov; 30(10):1522-8. PubMed ID: 21040406
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A Frizzled-Like Cysteine-Rich Domain in Glypican-3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice.
    Li N; Wei L; Liu X; Bai H; Ye Y; Li D; Li N; Baxa U; Wang Q; Lv L; Chen Y; Feng M; Lee B; Gao W; Ho M
    Hepatology; 2019 Oct; 70(4):1231-1245. PubMed ID: 30963603
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy.
    Gao W; Kim H; Feng M; Phung Y; Xavier CP; Rubin JS; Ho M
    Hepatology; 2014 Aug; 60(2):576-87. PubMed ID: 24492943
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling.
    Zheng X; Gai X; Han S; Moser CD; Hu C; Shire AM; Floyd RA; Roberts LR
    Genes Chromosomes Cancer; 2013 Mar; 52(3):225-36. PubMed ID: 23109092
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Both glypican-3/Wnt/β-catenin signaling pathway and autophagy contributed to the inhibitory effect of curcumin on hepatocellular carcinoma.
    Hu P; Ke C; Guo X; Ren P; Tong Y; Luo S; He Y; Wei Z; Cheng B; Li R; Luo J; Meng Z
    Dig Liver Dis; 2019 Jan; 51(1):120-126. PubMed ID: 30001951
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Association of glypican-3 expression with growth signaling molecules in hepatocellular carcinoma.
    Akutsu N; Yamamoto H; Sasaki S; Taniguchi H; Arimura Y; Imai K; Shinomura Y
    World J Gastroenterol; 2010 Jul; 16(28):3521-8. PubMed ID: 20653060
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human Monoclonal Antibody Targeting the Heparan Sulfate Chains of Glypican-3 Inhibits HGF-Mediated Migration and Motility of Hepatocellular Carcinoma Cells.
    Gao W; Kim H; Ho M
    PLoS One; 2015; 10(9):e0137664. PubMed ID: 26332121
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.
    Lai JP; Thompson JR; Sandhu DS; Roberts LR
    Future Oncol; 2008 Dec; 4(6):803-14. PubMed ID: 19086847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration.
    Nakamura I; Fernandez-Barrena MG; Ortiz-Ruiz MC; Almada LL; Hu C; Elsawa SF; Mills LD; Romecin PA; Gulaid KH; Moser CD; Han JJ; Vrabel A; Hanse EA; Akogyeram NA; Albrecht JH; Monga SPS; Sanderson SO; Prieto J; Roberts LR; Fernandez-Zapico ME
    J Biol Chem; 2013 Jul; 288(29):21389-21398. PubMed ID: 23740243
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling.
    Midorikawa Y; Ishikawa S; Iwanari H; Imamura T; Sakamoto H; Miyazono K; Kodama T; Makuuchi M; Aburatani H
    Int J Cancer; 2003 Feb; 103(4):455-65. PubMed ID: 12478660
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo.
    Zittermann SI; Capurro MI; Shi W; Filmus J
    Int J Cancer; 2010 Mar; 126(6):1291-301. PubMed ID: 19816934
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Shed antigen-induced blocking effect on CAR-T cells targeting Glypican-3 in Hepatocellular Carcinoma.
    Sun L; Gao F; Gao Z; Ao L; Li N; Ma S; Jia M; Li N; Lu P; Sun B; Ho M; Jia S; Ding T; Gao W
    J Immunother Cancer; 2021 Apr; 9(4):. PubMed ID: 33833049
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antineoplastic Activity of Chrysin against Human Hepatocellular Carcinoma: New Insight on GPC3/SULF2 Axis and lncRNA-AF085935 Expression.
    Sherif IO; Al-Mutabagani LA; Sabry D; Elsherbiny NM
    Int J Mol Sci; 2020 Oct; 21(20):. PubMed ID: 33076548
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma growth.
    Capurro MI; Shi W; Sandal S; Filmus J
    J Biol Chem; 2005 Dec; 280(50):41201-6. PubMed ID: 16227623
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role and mechanism of HIF-1α-mediated glypican-3 secretion in hypoxia-induced tumor progression in hepatocellular carcinoma.
    Wang P; Tong K; Li Y; Li X; Zhang Y; Gu J; Lei P; Yan S; Hu P
    Cell Signal; 2024 Feb; 114():111007. PubMed ID: 38081444
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of glypican 3 inhibits growth of hepatocellular carcinoma cells through up-regulation of TGF-β2.
    Sun CK; Chua MS; He J; So SK
    Neoplasia; 2011 Aug; 13(8):735-47. PubMed ID: 21847365
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: associated signaling pathways, tumor phenotypes, and survival.
    Yang JD; Sun Z; Hu C; Lai J; Dove R; Nakamura I; Lee JS; Thorgeirsson SS; Kang KJ; Chu IS; Roberts LR
    Genes Chromosomes Cancer; 2011 Feb; 50(2):122-35. PubMed ID: 21104785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling.
    Capurro MI; Xiang YY; Lobe C; Filmus J
    Cancer Res; 2005 Jul; 65(14):6245-54. PubMed ID: 16024626
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.