191 related articles for article (PubMed ID: 20726001)
1. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer.
Abdull Razis AF; Iori R; Ioannides C
Int J Cancer; 2011 Jun; 128(12):2775-82. PubMed ID: 20726001
[TBL] [Abstract][Full Text] [Related]
2. Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality.
Abdull Razis AF; Bagatta M; De Nicola GR; Iori R; Ioannides C
Arch Toxicol; 2011 Aug; 85(8):919-27. PubMed ID: 21132492
[TBL] [Abstract][Full Text] [Related]
3. Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes.
Gerhäuser C; You M; Liu J; Moriarty RM; Hawthorne M; Mehta RG; Moon RC; Pezzuto JM
Cancer Res; 1997 Jan; 57(2):272-8. PubMed ID: 9000567
[TBL] [Abstract][Full Text] [Related]
4. Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane.
Hanlon N; Coldham N; Sauer MJ; Ioannides C
Chem Biol Interact; 2009 Jan; 177(2):115-20. PubMed ID: 18823965
[TBL] [Abstract][Full Text] [Related]
5. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.
Zhang Y; Talalay P; Cho CG; Posner GH
Proc Natl Acad Sci U S A; 1992 Mar; 89(6):2399-403. PubMed ID: 1549603
[TBL] [Abstract][Full Text] [Related]
6. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity.
Yoxall V; Kentish P; Coldham N; Kuhnert N; Sauer MJ; Ioannides C
Int J Cancer; 2005 Nov; 117(3):356-62. PubMed ID: 15906351
[TBL] [Abstract][Full Text] [Related]
7. Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin.
Abdull Razis AF; Bagatta M; De Nicola GR; Iori R; Ioannides C
Lung Cancer; 2011 Mar; 71(3):298-305. PubMed ID: 20638746
[TBL] [Abstract][Full Text] [Related]
8. Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an isothiocyanate structurally related to sulforaphane.
Hanlon N; Okpara A; Coldham N; Sauer MJ; Ioannides C
J Agric Food Chem; 2008 Sep; 56(17):7866-71. PubMed ID: 18680373
[TBL] [Abstract][Full Text] [Related]
9. A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.
Abdull Razis AF; De Nicola GR; Pagnotta E; Iori R; Ioannides C
Eur J Nutr; 2013 Apr; 52(3):1279-85. PubMed ID: 22710810
[TBL] [Abstract][Full Text] [Related]
10. Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane.
Hanlon N; Coldham N; Sauer MJ; Ioannides C
Toxicology; 2008 Oct; 252(1-3):92-8. PubMed ID: 18773935
[TBL] [Abstract][Full Text] [Related]
11. The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.
Abdull Razis AF; Hanlon N; Soltys E; Krizova V; Iori R; Plant KE; Plant N; Ioannides C
Arch Toxicol; 2012 Oct; 86(10):1505-14. PubMed ID: 22643862
[TBL] [Abstract][Full Text] [Related]
12. Sulforaphane-mediated induction of a phase 2 detoxifying enzyme NAD(P)H:quinone reductase and apoptosis in human lymphoblastoid cells.
Misiewicz I; Skupińska K; Kowalska E; Lubiński J; Kasprzycka-Guttman T
Acta Biochim Pol; 2004; 51(3):711-21. PubMed ID: 15448733
[TBL] [Abstract][Full Text] [Related]
13. The aliphatic isothiocyanates erucin and sulforaphane do not effectively up-regulate NAD(P)H:quinone oxidoreductase (NQO1) in human liver compared with rat.
Hanlon N; Poynton CL; Coldham N; Sauer MJ; Ioannides C
Mol Nutr Food Res; 2009 Jul; 53(7):836-44. PubMed ID: 19536870
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes.
Posner GH; Cho CG; Green JV; Zhang Y; Talalay P
J Med Chem; 1994 Jan; 37(1):170-6. PubMed ID: 8289191
[TBL] [Abstract][Full Text] [Related]
15. The cruciferous nitrile crambene has bioactivity similar to sulforaphane when administered to Fischer 344 rats but is far less potent in cell culture.
Keck AS; Staack R; Jeffery EH
Nutr Cancer; 2002; 42(2):233-40. PubMed ID: 12416265
[TBL] [Abstract][Full Text] [Related]
16. 4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent.
Abdull Razis AF; De Nicola GR; Pagnotta E; Iori R; Ioannides C
Arch Toxicol; 2012 Feb; 86(2):183-94. PubMed ID: 21960141
[TBL] [Abstract][Full Text] [Related]
17. Sulforaphane is superior to glucoraphanin in modulating carcinogen-metabolising enzymes in Hep G2 cells.
Abdull Razis AF; Noor NM
Asian Pac J Cancer Prev; 2013; 14(7):4235-8. PubMed ID: 23991982
[TBL] [Abstract][Full Text] [Related]
18. Potent induction of phase 2 enzymes in human prostate cells by sulforaphane.
Brooks JD; Paton VG; Vidanes G
Cancer Epidemiol Biomarkers Prev; 2001 Sep; 10(9):949-54. PubMed ID: 11535546
[TBL] [Abstract][Full Text] [Related]
19. Differential response of four human livers to modulation of phase II enzyme systems by the chemopreventive phytochemical phenethyl isothiocyanate.
Konsue N; Ioannides C
Mol Nutr Food Res; 2010 Oct; 54(10):1477-85. PubMed ID: 20440691
[TBL] [Abstract][Full Text] [Related]
20. Cancer chemopreventive activity of sulforamate derivatives.
Moriarty RM; Naithani R; Kosmeder J; Prakash O
Eur J Med Chem; 2006 Jan; 41(1):121-4. PubMed ID: 16300858
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
