These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 20727750)

  • 1. Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.
    Chowdhury MA; Huang Z; Abdellatif KR; Dong Y; Yu G; Velázquez CA; Knaus EE
    Bioorg Med Chem Lett; 2010 Oct; 20(19):5776-80. PubMed ID: 20727750
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Yu G; Velázquez CA; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2009 Dec; 19(24):6855-61. PubMed ID: 19884005
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase.
    Yu G; Praveen Rao PN; Chowdhury MA; Abdellatif KR; Dong Y; Das D; Velázquez CA; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2010 Apr; 20(7):2168-73. PubMed ID: 20202839
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    J Med Chem; 2009 Mar; 52(6):1525-9. PubMed ID: 19296694
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.
    Lai Y; Ma L; Huang W; Yu X; Zhang Y; Ji H; Tian J
    Bioorg Med Chem Lett; 2010 Dec; 20(24):7349-53. PubMed ID: 21055929
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
    Özadalı K; Özkanlı F; Jain S; Rao PP; Velázquez-Martínez CA
    Bioorg Med Chem; 2012 May; 20(9):2912-22. PubMed ID: 22475926
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aspirin analogues as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, nitric oxide release, molecular modeling, and biological evaluation as anti-inflammatory agents.
    Kaur J; Bhardwaj A; Huang Z; Knaus EE
    ChemMedChem; 2012 Jan; 7(1):144-50. PubMed ID: 22095955
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Yu G; Chowdhury MA; Abdellatif KR; Dong Y; Praveen Rao PN; Das D; Velázquez CA; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2010 Feb; 20(3):896-902. PubMed ID: 20045320
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs).
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Dec; 14(23):7898-909. PubMed ID: 16904331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
    Tan CM; Chen GS; Chen CS; Chang PT; Chern JW
    Bioorg Med Chem; 2011 Nov; 19(21):6316-28. PubMed ID: 21958737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-(N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Rahman M; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2009 Feb; 19(3):584-8. PubMed ID: 19136259
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase.
    Li Y; Chen SH; Ou TM; Tan JH; Li D; Gu LQ; Huang ZS
    Bioorg Med Chem; 2011 Mar; 19(6):2074-83. PubMed ID: 21349729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.
    Moreau A; Chen QH; Praveen Rao PN; Knaus EE
    Bioorg Med Chem; 2006 Dec; 14(23):7716-27. PubMed ID: 16931030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
    Lamie PF; Ali WAM; Bazgier V; Rárová L
    Eur J Med Chem; 2016 Nov; 123():803-813. PubMed ID: 27541263
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors.
    Reddy MV; Billa VK; Pallela VR; Mallireddigari MR; Boominathan R; Gabriel JL; Reddy EP
    Bioorg Med Chem; 2008 Apr; 16(7):3907-16. PubMed ID: 18272371
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of glycolamide esters of indomethacin as potential cyclooxygenase-2 (COX-2) inhibitors.
    Khanna S; Madan M; Vangoori A; Banerjee R; Thaimattam R; Jafar Sadik Basha SK; Ramesh M; Casturi SR; Pal M
    Bioorg Med Chem; 2006 Jul; 14(14):4820-33. PubMed ID: 16581252
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
    Cusan C; Spalluto G; Prato M; Adams M; Bodensieck A; Bauer R; Tubaro A; Bernardi P; Da Ros T
    Farmaco; 2005 Apr; 60(4):327-32. PubMed ID: 15848208
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
    Pontiki E; Hadjipavlou-Litina D; Litinas K; Nicolotti O; Carotti A
    Eur J Med Chem; 2011 Jan; 46(1):191-200. PubMed ID: 21106277
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.