These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

113 related articles for article (PubMed ID: 20732331)

  • 1. Diversity of bisubstrate binding modes of adenosine analogue-oligoarginine conjugates in protein kinase a and implications for protein substrate interactions.
    Pflug A; Rogozina J; Lavogina D; Enkvist E; Uri A; Engh RA; Bossemeyer D
    J Mol Biol; 2010 Oct; 403(1):66-77. PubMed ID: 20732331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of CREB phosphorylation by conjugates of adenosine analogues and arginine-rich peptides, inhibitors of PKA catalytic subunit.
    Kriisa M; Sinijärv H; Vaasa A; Enkvist E; Kostenko S; Moens U; Uri A
    Chembiochem; 2015 Jan; 16(2):312-9. PubMed ID: 25487811
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of RIalpha subunit of cyclic adenosine 5'-monophosphate (cAMP)-dependent protein kinase complexed with (Rp)-adenosine 3',5'-cyclic monophosphothioate and (Sp)-adenosine 3',5'-cyclic monophosphothioate, the phosphothioate analogues of cAMP.
    Wu J; Jones JM; Nguyen-Huu X; Ten Eyck LF; Taylor SS
    Biochemistry; 2004 Jun; 43(21):6620-9. PubMed ID: 15157095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of the ability of highly charged nanomolar inhibitors of protein kinases to cross plasma membranes and carry a protein into cells.
    Uri A; Raidaru G; Subbi J; Padari K; Pooga M
    Bioorg Med Chem Lett; 2002 Aug; 12(16):2117-20. PubMed ID: 12127517
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein kinases.
    Lavogina D; Lust M; Viil I; König N; Raidaru G; Rogozina J; Enkvist E; Uri A; Bossemeyer D
    J Med Chem; 2009 Jan; 52(2):308-21. PubMed ID: 19143565
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility.
    Narayana N; Cox S; Nguyen-huu X; Ten Eyck LF; Taylor SS
    Structure; 1997 Jul; 5(7):921-35. PubMed ID: 9261084
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conjugation of adenosine and hexa-(D-arginine) leads to a nanomolar bisubstrate-analog inhibitor of basophilic protein kinases.
    Enkvist E; Lavogina D; Raidaru G; Vaasa A; Viil I; Lust M; Viht K; Uri A
    J Med Chem; 2006 Nov; 49(24):7150-9. PubMed ID: 17125267
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of a polyhistidine-tagged recombinant catalytic subunit of cAMP-dependent protein kinase complexed with the peptide inhibitor PKI(5-24) and adenosine.
    Narayana N; Cox S; Shaltiel S; Taylor SS; Xuong N
    Biochemistry; 1997 Apr; 36(15):4438-48. PubMed ID: 9109651
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of the structure of adenosine mimic of bisubstrate-analog inhibitors on their activity towards basophilic protein kinases.
    Enkvist E; Kriisa M; Roben M; Kadak G; Raidaru G; Uri A
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6098-101. PubMed ID: 19800227
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Small-molecule FRET probes for protein kinase activity monitoring in living cells.
    Vaasa A; Lust M; Terrin A; Uri A; Zaccolo M
    Biochem Biophys Res Commun; 2010 Jul; 397(4):750-5. PubMed ID: 20541535
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit.
    Akamine P; Madhusudan ; Brunton LL; Ou HD; Canaves JM; Xuong NH; Taylor SS
    Biochemistry; 2004 Jan; 43(1):85-96. PubMed ID: 14705934
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanism-based design of a protein kinase inhibitor.
    Parang K; Till JH; Ablooglu AJ; Kohanski RA; Hubbard SR; Cole PA
    Nat Struct Biol; 2001 Jan; 8(1):37-41. PubMed ID: 11135668
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Surface-plasmon-resonance-based biosensor with immobilized bisubstrate analog inhibitor for the determination of affinities of ATP- and protein-competitive ligands of cAMP-dependent protein kinase.
    Viht K; Schweinsberg S; Lust M; Vaasa A; Raidaru G; Lavogina D; Uri A; Herberg FW
    Anal Biochem; 2007 Mar; 362(2):268-77. PubMed ID: 17274940
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants.
    Breitenlechner CB; Friebe WG; Brunet E; Werner G; Graul K; Thomas U; Künkele KP; Schäfer W; Gassel M; Bossemeyer D; Huber R; Engh RA; Masjost B
    J Med Chem; 2005 Jan; 48(1):163-70. PubMed ID: 15634010
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity.
    Kovalevsky AY; Johnson H; Hanson BL; Waltman MJ; Fisher SZ; Taylor S; Langan P
    Acta Crystallogr D Biol Crystallogr; 2012 Jul; 68(Pt 7):854-60. PubMed ID: 22751671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insights into the phosphoryl transfer catalyzed by cAMP-dependent protein kinase: an X-ray crystallographic study of complexes with various metals and peptide substrate SP20.
    Gerlits O; Waltman MJ; Taylor S; Langan P; Kovalevsky A
    Biochemistry; 2013 May; 52(21):3721-7. PubMed ID: 23672593
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Adenosine analogue-oligo-arginine conjugates (ARCs) serve as high-affinity inhibitors and fluorescence probes of type I cGMP-dependent protein kinase (PKGIalpha).
    Lavogina D; Nickl CK; Enkvist E; Raidaru G; Lust M; Vaasa A; Uri A; Dostmann WR
    Biochim Biophys Acta; 2010 Sep; 1804(9):1857-68. PubMed ID: 20406699
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase.
    Narayana N; Diller TC; Koide K; Bunnage ME; Nicolaou KC; Brunton LL; Xuong NH; Ten Eyck LF; Taylor SS
    Biochemistry; 1999 Feb; 38(8):2367-76. PubMed ID: 10029530
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity.
    Engh RA; Girod A; Kinzel V; Huber R; Bossemeyer D
    J Biol Chem; 1996 Oct; 271(42):26157-64. PubMed ID: 8824261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-resolution crystal structure of cAMP-dependent protein kinase from Cricetulus griseus.
    Kudlinzki D; Linhard VL; Saxena K; Sreeramulu S; Gande S; Schieborr U; Dreyer M; Schwalbe H
    Acta Crystallogr F Struct Biol Commun; 2015 Aug; 71(Pt 8):1088-93. PubMed ID: 26249705
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.