135 related articles for article (PubMed ID: 20735986)
1. Development of an efficient E. coli expression and purification system for a catalytically active, human Cullin3-RINGBox1 protein complex and elucidation of its quaternary structure with Keap1.
Small E; Eggler A; Mesecar AD
Biochem Biophys Res Commun; 2010 Oct; 400(4):471-5. PubMed ID: 20735986
[TBL] [Abstract][Full Text] [Related]
2. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
Baird L; Dinkova-Kostova AT
Biochem Biophys Res Commun; 2013 Mar; 433(1):58-65. PubMed ID: 23454126
[TBL] [Abstract][Full Text] [Related]
3. Cryo-EM structure of the KLHL22 E3 ligase bound to an oligomeric metabolic enzyme.
Teng F; Wang Y; Liu M; Tian S; Stjepanovic G; Su MY
Structure; 2023 Nov; 31(11):1431-1440.e5. PubMed ID: 37788672
[TBL] [Abstract][Full Text] [Related]
4. Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.
Martinez VD; Vucic EA; Thu KL; Pikor LA; Hubaux R; Lam WL
Biomed Res Int; 2014; 2014():159459. PubMed ID: 25114896
[TBL] [Abstract][Full Text] [Related]
5. Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.
Martinez VD; Vucic EA; Pikor LA; Thu KL; Hubaux R; Lam WL
Mol Cancer; 2013 Oct; 12(1):124. PubMed ID: 24138990
[TBL] [Abstract][Full Text] [Related]
6. Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer.
Martinez VD; Vucic EA; Thu KL; Pikor LA; Lam S; Lam WL
Head Neck; 2015 May; 37(5):727-34. PubMed ID: 24596130
[TBL] [Abstract][Full Text] [Related]
7. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
[TBL] [Abstract][Full Text] [Related]
8. Regulation of the Nrf2-Keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases.
Villeneuve NF; Lau A; Zhang DD
Antioxid Redox Signal; 2010 Dec; 13(11):1699-712. PubMed ID: 20486766
[TBL] [Abstract][Full Text] [Related]
9. New strategies to inhibit KEAP1 and the Cul3-based E3 ubiquitin ligases.
Canning P; Bullock AN
Biochem Soc Trans; 2014 Feb; 42(1):103-7. PubMed ID: 24450635
[TBL] [Abstract][Full Text] [Related]
10. Tetrachlorobenzoquinone activates Nrf2 signaling by Keap1 cross-linking and ubiquitin translocation but not Keap1-Cullin3 complex dissociation.
Su C; Zhang P; Song X; Shi Q; Fu J; Xia X; Bai H; Hu L; Xu D; Song E; Song Y
Chem Res Toxicol; 2015 Apr; 28(4):765-74. PubMed ID: 25742418
[TBL] [Abstract][Full Text] [Related]
11. Identification and Characterization of MCM3 as a Kelch-like ECH-associated Protein 1 (KEAP1) Substrate.
Mulvaney KM; Matson JP; Siesser PF; Tamir TY; Goldfarb D; Jacobs TM; Cloer EW; Harrison JS; Vaziri C; Cook JG; Major MB
J Biol Chem; 2016 Nov; 291(45):23719-23733. PubMed ID: 27621311
[TBL] [Abstract][Full Text] [Related]
12. Structural basis for Cullins and RING component inhibition: Targeting E3 ubiquitin pathway conductors for cancer therapeutics.
Shafique S; Ali W; Kanwal S; Rashid S
Int J Biol Macromol; 2018 Jan; 106():532-543. PubMed ID: 28802844
[TBL] [Abstract][Full Text] [Related]
13. Heteroaromatic 4-arylquinols are novel inducers of nuclear factor-erythroid 2-related factor 2 (Nrf2).
Wong DP; Wells G; Hagen T
Eur J Pharmacol; 2010 Sep; 643(2-3):188-94. PubMed ID: 20599909
[TBL] [Abstract][Full Text] [Related]
14. Arsenite Targets the RING Finger Domain of Rbx1 E3 Ubiquitin Ligase to Inhibit Proteasome-Mediated Degradation of Nrf2.
Jiang J; Tam LM; Wang P; Wang Y
Chem Res Toxicol; 2018 May; 31(5):380-387. PubMed ID: 29658272
[TBL] [Abstract][Full Text] [Related]
15. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
[TBL] [Abstract][Full Text] [Related]
16. Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3.
Gao L; Wang J; Sekhar KR; Yin H; Yared NF; Schneider SN; Sasi S; Dalton TP; Anderson ME; Chan JY; Morrow JD; Freeman ML
J Biol Chem; 2007 Jan; 282(4):2529-37. PubMed ID: 17127771
[TBL] [Abstract][Full Text] [Related]
17. Characterization of the Cullin7 E3 ubiquitin ligase--heterodimerization of cullin substrate receptors as a novel mechanism to regulate cullin E3 ligase activity.
Ponyeam W; Hagen T
Cell Signal; 2012 Jan; 24(1):290-5. PubMed ID: 21946088
[TBL] [Abstract][Full Text] [Related]
18. Keap1/Cullin3 Modulates p62/SQSTM1 Activity via UBA Domain Ubiquitination.
Lee Y; Chou TF; Pittman SK; Keith AL; Razani B; Weihl CC
Cell Rep; 2017 Apr; 19(1):188-202. PubMed ID: 28380357
[TBL] [Abstract][Full Text] [Related]
19. Cullin 3 and Its Role in Tumorigenesis.
Chen RH
Adv Exp Med Biol; 2020; 1217():187-210. PubMed ID: 31898229
[TBL] [Abstract][Full Text] [Related]
20. Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.
Eggler AL; Small E; Hannink M; Mesecar AD
Biochem J; 2009 Jul; 422(1):171-80. PubMed ID: 19489739
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
