126 related articles for article (PubMed ID: 20738383)
1. Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.
Pessah N; Kaufmann D; Yagen B; Hen N; Wlodarczyk B; Finnell RH; Bialer M
Epilepsia; 2010 Oct; 51(10):1944-53. PubMed ID: 20738383
[TBL] [Abstract][Full Text] [Related]
2. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.
Pessah N; Bialer M; Wlodarczyk B; Finnell RH; Yagen B
J Med Chem; 2009 Apr; 52(8):2233-42. PubMed ID: 19296679
[TBL] [Abstract][Full Text] [Related]
3. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.
Sobol E; Yagen B; Lamb JG; White HS; Wlodarczyk BJ; Finnell RH; Bialer M
Epilepsy Res; 2007 Jan; 73(1):75-84. PubMed ID: 16997532
[TBL] [Abstract][Full Text] [Related]
4. Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: evaluation of the teratogenic effects of its amide derivatives in NMRI mice.
Okada A; Onishi Y; Yagen B; Shimshoni JA; Kaufmann D; Bialer M; Fujiwara M
Birth Defects Res A Clin Mol Teratol; 2008 Sep; 82(9):610-21. PubMed ID: 18671279
[TBL] [Abstract][Full Text] [Related]
5. Pharmacokinetic analysis and antiepileptic activity of tetra-methylcyclopropane analogues of valpromide.
Bialer M; Hadad S; Kadry B; Abdul-Hai A; Haj-Yehia A; Sterling J; Herzig Y; Yagen B
Pharm Res; 1996 Feb; 13(2):284-9. PubMed ID: 8932450
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid.
Kaufmann D; Yagen B; Minert A; Wlodarczyk B; Finnell RH; Schurig V; Devor M; Bialer M
Neuropharmacology; 2010 Jun; 58(8):1228-36. PubMed ID: 20230843
[TBL] [Abstract][Full Text] [Related]
7. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
Shimshoni JA; Bialer M; Wlodarczyk B; Finnell RH; Yagen B
J Med Chem; 2007 Dec; 50(25):6419-27. PubMed ID: 17994680
[TBL] [Abstract][Full Text] [Related]
8. Teratology study of derivatives of tetramethylcyclopropyl amide analogues of valproic acid in mice.
Okada A; Onishi Y; Aoki Y; Yagen B; Sobol E; Bialer M; Fujiwara M
Birth Defects Res B Dev Reprod Toxicol; 2006 Jun; 77(3):227-33. PubMed ID: 16767757
[TBL] [Abstract][Full Text] [Related]
9. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.
Shimshoni JA; Yagen B; Wlodarczyk B; Finnell RH; Schurig V; Bialer M
Epilepsia; 2010 Mar; 51(3):323-32. PubMed ID: 19674061
[TBL] [Abstract][Full Text] [Related]
10. Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.
Okada A; Noyori H; Yagen B; Shimshoni JA; Bialer M; Fujiwara M
Birth Defects Res B Dev Reprod Toxicol; 2009 Oct; 86(5):394-401. PubMed ID: 19830722
[TBL] [Abstract][Full Text] [Related]
11. Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.
Sobol E; Bialer M; Yagen B
J Med Chem; 2004 Aug; 47(17):4316-26. PubMed ID: 15294003
[TBL] [Abstract][Full Text] [Related]
12. Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug.
Isoherranen N; White HS; Finnell RH; Yagen B; Woodhead JH; Bennett GD; Wilcox KS; Barton ME; Bialer M
Epilepsia; 2002 Feb; 43(2):115-26. PubMed ID: 11903457
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues.
Kaufmann D; Bialer M; Shimshoni JA; Devor M; Yagen B
J Med Chem; 2009 Nov; 52(22):7236-48. PubMed ID: 19877649
[TBL] [Abstract][Full Text] [Related]
14. Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain.
Winkler I; Sobol E; Yagen B; Steinman A; Devor M; Bialer M
Neuropharmacology; 2005 Dec; 49(8):1110-20. PubMed ID: 16055160
[TBL] [Abstract][Full Text] [Related]
15. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.
Shimshoni JA; Yagen B; Pessah N; Wlodarczyk B; Finnell RH; Bialer M
Epilepsia; 2008 Jul; 49(7):1202-12. PubMed ID: 18435754
[TBL] [Abstract][Full Text] [Related]
16. Pharmacokinetic and pharmacodynamic analysis of (E)-2-ene valproyl derivatives of glycine and valproyl derivatives of nipecotic acid.
Bialer M; Kadry B; Abdul-Hai A; Haj-Yehia A; Sterling J; Herzig Y; Shirvan M
Biopharm Drug Dispos; 1996 Oct; 17(7):565-75. PubMed ID: 8894115
[TBL] [Abstract][Full Text] [Related]
17. Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.
Gravemann U; Volland J; Nau H
Neurotoxicol Teratol; 2008; 30(5):390-4. PubMed ID: 18455366
[TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetic considerations in the design of better and safer new antiepileptic drugs.
Bialer M
J Control Release; 1999 Nov; 62(1-2):187-92. PubMed ID: 10518650
[TBL] [Abstract][Full Text] [Related]
19. Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
Mawasi H; Shekh-Ahmad T; Finnell RH; Wlodarczyk BJ; Bialer M
Epilepsy Behav; 2015 May; 46():72-8. PubMed ID: 25863940
[TBL] [Abstract][Full Text] [Related]
20. Disposition of two tetramethylcyclopropane analogues of valpromide in the brain, liver, plasma and urine of rats.
Blotnik S; Bergman F; Bialer M
Eur J Pharm Sci; 1998 Apr; 6(2):93-8. PubMed ID: 9795021
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]