BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 20740228)

  • 1. A fluopol-ABPP HTS assay to identify PAD inhibitors.
    Knuckley B; Jones JE; Bachovchin DA; Slack J; Causey CP; Brown SJ; Rosen H; Cravatt BF; Thompson PR
    Chem Commun (Camb); 2010 Oct; 46(38):7175-7. PubMed ID: 20740228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insights into the mechanism of streptonigrin-induced protein arginine deiminase inactivation.
    Dreyton CJ; Anderson ED; Subramanian V; Boger DL; Thompson PR
    Bioorg Med Chem; 2014 Feb; 22(4):1362-9. PubMed ID: 24440480
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors.
    Knuckley B; Luo Y; Thompson PR
    Bioorg Med Chem; 2008 Jan; 16(2):739-45. PubMed ID: 17964793
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors.
    Jones JE; Slack JL; Fang P; Zhang X; Subramanian V; Causey CP; Coonrod SA; Guo M; Thompson PR
    ACS Chem Biol; 2012 Jan; 7(1):160-5. PubMed ID: 22004374
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3.
    Knuckley B; Causey CP; Jones JE; Bhatia M; Dreyton CJ; Osborne TC; Takahara H; Thompson PR
    Biochemistry; 2010 Jun; 49(23):4852-63. PubMed ID: 20469888
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein Arginine Deiminases (PADs): Biochemistry and Chemical Biology of Protein Citrullination.
    Mondal S; Thompson PR
    Acc Chem Res; 2019 Mar; 52(3):818-832. PubMed ID: 30844238
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential.
    Jones JE; Causey CP; Knuckley B; Slack-Noyes JL; Thompson PR
    Curr Opin Drug Discov Devel; 2009 Sep; 12(5):616-27. PubMed ID: 19736621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.
    Luo Y; Arita K; Bhatia M; Knuckley B; Lee YH; Stallcup MR; Sato M; Thompson PR
    Biochemistry; 2006 Oct; 45(39):11727-36. PubMed ID: 17002273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase.
    Lahav D; Liu B; van den Berg RJBHN; van den Nieuwendijk AMCH; Wennekes T; Ghisaidoobe AT; Breen I; Ferraz MJ; Kuo CL; Wu L; Geurink PP; Ovaa H; van der Marel GA; van der Stelt M; Boot RG; Davies GJ; Aerts JMFG; Overkleeft HS
    J Am Chem Soc; 2017 Oct; 139(40):14192-14197. PubMed ID: 28937220
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fluorescence-based monitoring of PAD4 activity via a pro-fluorescence substrate analog.
    Sabulski MJ; Fura JM; Pires MM
    J Vis Exp; 2014 Nov; (93):e52114. PubMed ID: 25407913
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of a new class of inhibitors for the protein arginine deiminase type 4 (PAD4) by structure-based virtual screening.
    Teo CY; Shave S; Chor AL; Salleh AB; Rahman MB; Walkinshaw MD; Tejo BA
    BMC Bioinformatics; 2012; 13 Suppl 17(Suppl 17):S4. PubMed ID: 23282142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A FluoPol-ABPP PAD2 high-throughput screen identifies the first calcium site inhibitor targeting the PADs.
    Lewallen DM; Bicker KL; Madoux F; Chase P; Anguish L; Coonrod S; Hodder P; Thompson PR
    ACS Chem Biol; 2014 Apr; 9(4):913-21. PubMed ID: 24467619
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4.
    Slack JL; Causey CP; Luo Y; Thompson PR
    ACS Chem Biol; 2011 May; 6(5):466-76. PubMed ID: 21265574
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors.
    Lone AM; Bachovchin DA; Westwood DB; Speers AE; Spicer TP; Fernandez-Vega V; Chase P; Hodder PS; Rosen H; Cravatt BF; Saghatelian A
    J Am Chem Soc; 2011 Aug; 133(30):11665-74. PubMed ID: 21692504
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Photochemical Control of Protein Arginine Deiminase (PAD) Activity.
    Mondal S; Parelkar SS; Nagar M; Thompson PR
    ACS Chem Biol; 2018 Apr; 13(4):1057-1065. PubMed ID: 29517899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation.
    Luo Y; Knuckley B; Lee YH; Stallcup MR; Thompson PR
    J Am Chem Soc; 2006 Feb; 128(4):1092-3. PubMed ID: 16433522
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Peptidomimetics as protein arginine deiminase 4 (PAD4) inhibitors.
    Trabocchi A; Pala N; Krimmelbein I; Menchi G; Guarna A; Sechi M; Dreker T; Scozzafava A; Supuran CT; Carta F
    J Enzyme Inhib Med Chem; 2015 Jun; 30(3):466-71. PubMed ID: 25198885
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of a highly sensitive fluorescence probe for peptidyl arginine deiminase (PAD) activity.
    Kunieda K; Kawaguchi M; Ieda N; Nakagawa H
    Bioorg Med Chem Lett; 2019 Apr; 29(7):923-928. PubMed ID: 30773431
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of Novel Potential Reversible Peptidyl Arginine Deiminase Inhibitor.
    Aliko A; Kamińska M; Falkowski K; Bielecka E; Benedyk-Machaczka M; Malicki S; Kozieł J; Wong A; Bryzek D; Kantyka T; Mydel P
    Int J Mol Sci; 2019 May; 20(9):. PubMed ID: 31052493
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 10.