158 related articles for article (PubMed ID: 20800599)
1. Enhancer and competitive allosteric modulation model for G-protein-coupled receptors.
Pietra D; Borghini A; Breschi MC; Bianucci AM
J Theor Biol; 2010 Dec; 267(4):663-75. PubMed ID: 20800599
[TBL] [Abstract][Full Text] [Related]
2. Allosteric enhancers of A1 adenosine receptors increase receptor-G protein coupling and counteract Guanine nucleotide effects on agonist binding.
Figler H; Olsson RA; Linden J
Mol Pharmacol; 2003 Dec; 64(6):1557-64. PubMed ID: 14645687
[TBL] [Abstract][Full Text] [Related]
3. Hybrid ortho/allosteric ligands for the adenosine A(1) receptor.
Narlawar R; Lane JR; Doddareddy M; Lin J; Brussee J; Ijzerman AP
J Med Chem; 2010 Apr; 53(8):3028-37. PubMed ID: 20345101
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological effects of novel 2-amino-3-naphthoylthiophenes as allosteric enhancers of the A1 adenosine receptor.
Baraldi PG; Romagnoli R; Pavani MG; Nuñez Mdel C; Tabrizi MA; Shryock JC; Leung E; Moorman AR; Uluoglu C; Iannotta V; Merighi S; Borea PA
J Med Chem; 2003 Feb; 46(5):794-809. PubMed ID: 12593659
[TBL] [Abstract][Full Text] [Related]
5. Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects.
Valant C; Felder CC; Sexton PM; Christopoulos A
Mol Pharmacol; 2012 Jan; 81(1):41-52. PubMed ID: 21989256
[TBL] [Abstract][Full Text] [Related]
6. Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.
Barrondo S; Sallés J
Neuropharmacology; 2009 Feb; 56(2):455-62. PubMed ID: 18951909
[TBL] [Abstract][Full Text] [Related]
7. Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptors.
Avlani V; May LT; Sexton PM; Christopoulos A
J Pharmacol Exp Ther; 2004 Mar; 308(3):1062-72. PubMed ID: 14711931
[TBL] [Abstract][Full Text] [Related]
8. The allosteric enhancer PD81,723 increases chimaeric A1/A2A adenosine receptor coupling with Gs.
Bhattacharya S; Youkey RL; Ghartey K; Leonard M; Linden J; Tucker AL
Biochem J; 2006 May; 396(1):139-46. PubMed ID: 16390330
[TBL] [Abstract][Full Text] [Related]
9. Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.
Casadó V; Ferrada C; Bonaventura J; Gracia E; Mallol J; Canela EI; Lluís C; Cortés A; Franco R
Biochem Pharmacol; 2009 Dec; 78(12):1456-63. PubMed ID: 19643089
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological characterization of [3H] (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(4-chlorophenyl)-methanone, the first radiolabelled adenosine A1 allosteric enhancer.
Baraldi PG; Pavani MG; Leung E; Moorman AR; Varani K; Vincenzi F; Borea PA; Romagnoli R
Bioorg Med Chem Lett; 2006 Mar; 16(5):1402-4. PubMed ID: 16321527
[TBL] [Abstract][Full Text] [Related]
11. The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.
Avlani VA; McLoughlin DJ; Sexton PM; Christopoulos A
J Pharmacol Exp Ther; 2008 Jun; 325(3):927-34. PubMed ID: 18322151
[TBL] [Abstract][Full Text] [Related]
12. N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.
Urwyler S; Pozza MF; Lingenhoehl K; Mosbacher J; Lampert C; Froestl W; Koller M; Kaupmann K
J Pharmacol Exp Ther; 2003 Oct; 307(1):322-30. PubMed ID: 12954816
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of 2-amino-3-heteroaroylthiophenes and evaluation of their activity as potential allosteric enhancers at the human A1 receptor.
Baraldi PG; Pavani MG; Shryock JC; Moorman AR; Iannotta V; Borea PA; Romagnoli R
Eur J Med Chem; 2004 Oct; 39(10):855-65. PubMed ID: 15464619
[TBL] [Abstract][Full Text] [Related]
14. Estimation of the affinities of allosteric ligands using radioligand binding and pharmacological null methods.
Ehlert FJ
Mol Pharmacol; 1988 Feb; 33(2):187-94. PubMed ID: 2828914
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of 2,3,5-substituted [1,2,4]thiadiazoles as allosteric modulators of adenosine receptors.
van den Nieuwendijk AM; Pietra D; Heitman L; Göblyös A; IJzerman AP
J Med Chem; 2004 Jan; 47(3):663-72. PubMed ID: 14736246
[TBL] [Abstract][Full Text] [Related]
16. The 'allosteric modulator' SCH-202676 disrupts G protein-coupled receptor function via sulphydryl-sensitive mechanisms.
Lewandowicz AM; Vepsäläinen J; Laitinen JT
Br J Pharmacol; 2006 Feb; 147(4):422-9. PubMed ID: 16402041
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological effects of novel 2-amino-3-(4-chlorobenzoyl)-4-substituted thiophenes as allosteric enhancers of the A1 adenosine receptor.
Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Kimatrai Salvador M; Preti D; Aghazadeh Tabrizi M; Moorman AR; Vincenzi F; Borea PA; Varani K
Eur J Med Chem; 2013 Sep; 67():409-27. PubMed ID: 23911855
[TBL] [Abstract][Full Text] [Related]
18. Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus.
Gracia E; Cortés A; Meana JJ; García-Sevilla J; Herhsfield MS; Canela EI; Mallol J; Lluís C; Franco R; Casadó V
J Neurochem; 2008 Oct; 107(1):161-70. PubMed ID: 18680557
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
Romagnoli R; Baraldi PG; Lopez-Cara C; Cruz-Lopez O; Moorman AR; Massink A; IJzerman AP; Vincenzi F; Borea PA; Varani K
Eur J Med Chem; 2015 Aug; 101():185-204. PubMed ID: 26141910
[TBL] [Abstract][Full Text] [Related]
20. Effects of long-term treatment with the allosteric enhancer, PD81,723, on Chinese hamster ovary cells expressing recombinant human A1 adenosine receptors.
Bhattacharya S; Linden J
Mol Pharmacol; 1996 Jul; 50(1):104-11. PubMed ID: 8700102
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
