BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 20801877)

  • 1. Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms.
    Vigil D; Martin TD; Williams F; Yeh JJ; Campbell SL; Der CJ
    J Biol Chem; 2010 Nov; 285(45):34729-40. PubMed ID: 20801877
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma.
    Yoshimachi S; Shirakawa R; Cao M; Trinh DA; Gao P; Sakata N; Miyazaki K; Goto K; Miura T; Ariake K; Maeda S; Masuda K; Ishida M; Ohtsuka H; Unno M; Horiuchi H
    Cancer Sci; 2021 Aug; 112(8):3064-3073. PubMed ID: 34009715
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.
    Lim KH; O'Hayer K; Adam SJ; Kendall SD; Campbell PM; Der CJ; Counter CM
    Curr Biol; 2006 Dec; 16(24):2385-94. PubMed ID: 17174914
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector.
    Neel NF; Rossman KL; Martin TD; Hayes TK; Yeh JJ; Der CJ
    Mol Cell Biol; 2012 Apr; 32(8):1374-86. PubMed ID: 22331470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential involvement of RalA and RalB in colorectal cancer.
    Martin TD; Der CJ
    Small GTPases; 2012; 3(2):126-30. PubMed ID: 22790202
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RalB directly triggers invasion downstream Ras by mobilizing the Wave complex.
    Zago G; Veith I; Singh MK; Fuhrmann L; De Beco S; Remorino A; Takaoka S; Palmeri M; Berger F; Brandon N; El Marjou A; Vincent-Salomon A; Camonis J; Coppey M; Parrini MC
    Elife; 2018 Oct; 7():. PubMed ID: 30320548
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of RalA is critical for Ras-induced tumorigenesis of human cells.
    Lim KH; Baines AT; Fiordalisi JJ; Shipitsin M; Feig LA; Cox AD; Der CJ; Counter CM
    Cancer Cell; 2005 Jun; 7(6):533-45. PubMed ID: 15950903
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases.
    Gentry LR; Nishimura A; Cox AD; Martin TD; Tsygankov D; Nishida M; Elston TC; Der CJ
    J Biol Chem; 2015 Sep; 290(37):22851-61. PubMed ID: 26216878
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ral GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformation.
    Tecleab A; Zhang X; Sebti SM
    J Biol Chem; 2014 Nov; 289(45):31296-309. PubMed ID: 25210032
    [TBL] [Abstract][Full Text] [Related]  

  • 10. κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis.
    Beel S; Kolloch L; Apken LH; Jürgens L; Bolle A; Sudhof N; Ghosh S; Wardelmann E; Meisterernst M; Steinestel K; Oeckinghaus A
    Nat Commun; 2020 Jul; 11(1):3409. PubMed ID: 32641778
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Localization of RalB signaling at endomembrane compartments and its modulation by autophagy.
    Singh MK; Martin APJ; Joffre C; Zago G; Camonis J; Coppey M; Parrini MC
    Sci Rep; 2019 Jun; 9(1):8910. PubMed ID: 31222145
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activation and involvement of Ral GTPases in colorectal cancer.
    Martin TD; Samuel JC; Routh ED; Der CJ; Yeh JJ
    Cancer Res; 2011 Jan; 71(1):206-15. PubMed ID: 21199803
    [TBL] [Abstract][Full Text] [Related]  

  • 13. R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.
    Takaya A; Kamio T; Masuda M; Mochizuki N; Sawa H; Sato M; Nagashima K; Mizutani A; Matsuno A; Kiyokawa E; Matsuda M
    Mol Biol Cell; 2007 May; 18(5):1850-60. PubMed ID: 17344481
    [TBL] [Abstract][Full Text] [Related]  

  • 14. K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling.
    Campbell PM; Groehler AL; Lee KM; Ouellette MM; Khazak V; Der CJ
    Cancer Res; 2007 Mar; 67(5):2098-106. PubMed ID: 17332339
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases.
    O Santos A; Parrini MC; Camonis J
    PLoS One; 2016; 11(5):e0154840. PubMed ID: 27149377
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ral GTPase Activation by Downregulation of RalGAP Enhances Oral Squamous Cell Carcinoma Progression.
    Gao P; Liu S; Yoshida R; Shi CY; Yoshimachi S; Sakata N; Goto K; Kimura T; Shirakawa R; Nakayama H; Sakata J; Kawashiri S; Kato K; Wang XY; Horiuchi H
    J Dent Res; 2019 Aug; 98(9):1011-1019. PubMed ID: 31329042
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ral small GTPase signaling and oncogenesis: More than just 15minutes of fame.
    Gentry LR; Martin TD; Reiner DJ; Der CJ
    Biochim Biophys Acta; 2014 Dec; 1843(12):2976-2988. PubMed ID: 25219551
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Response to MLN8237 in pancreatic cancer is not dependent on RalA phosphorylation.
    Neel NF; Stratford JK; Shinde V; Ecsedy JA; Martin TD; Der CJ; Yeh JJ
    Mol Cancer Ther; 2014 Jan; 13(1):122-33. PubMed ID: 24222664
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Involvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformation.
    Murphy GA; Graham SM; Morita S; Reks SE; Rogers-Graham K; Vojtek A; Kelley GG; Der CJ
    J Biol Chem; 2002 Mar; 277(12):9966-75. PubMed ID: 11788587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ras-related small GTPases RalA and RalB regulate cellular survival after ionizing radiation.
    Kidd AR; Snider JL; Martin TD; Graboski SF; Der CJ; Cox AD
    Int J Radiat Oncol Biol Phys; 2010 Sep; 78(1):205-12. PubMed ID: 20619549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.