BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 20803550)

  • 1. p53 and p21(Waf1) are recruited to distinct PML-containing nuclear foci in irradiated and Nutlin-3a-treated U2OS cells.
    Shen H; Maki CG
    J Cell Biochem; 2010 Dec; 111(5):1280-90. PubMed ID: 20803550
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.
    Lau LM; Nugent JK; Zhao X; Irwin MS
    Oncogene; 2008 Feb; 27(7):997-1003. PubMed ID: 17700533
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Knocking down PML impairs p53 signaling transduction pathway and suppresses irradiation induced apoptosis in breast carcinoma cell MCF-7.
    Bao-Lei T; Zhu-Zhong M; Yi S; Jun-Jie Q; Yan D; Hua L; Bin L; Guo-Wei Z; Zhi-Xian S
    J Cell Biochem; 2006 Feb; 97(3):561-71. PubMed ID: 16215989
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.
    Jiang WQ; Zhong ZH; Nguyen A; Henson JD; Toouli CD; Braithwaite AW; Reddel RR
    J Cell Biol; 2009 Jun; 185(5):797-810. PubMed ID: 19468068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of p53 with Nutlin-3a radiosensitizes lung cancer cells via enhancing radiation-induced premature senescence.
    Luo H; Yount C; Lang H; Yang A; Riemer EC; Lyons K; Vanek KN; Silvestri GA; Schulte BA; Wang GY
    Lung Cancer; 2013 Aug; 81(2):167-73. PubMed ID: 23683497
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HP1-mediated formation of alternative lengthening of telomeres-associated PML bodies requires HIRA but not ASF1a.
    Jiang WQ; Nguyen A; Cao Y; Chang AC; Reddel RR
    PLoS One; 2011 Feb; 6(2):e17036. PubMed ID: 21347226
    [TBL] [Abstract][Full Text] [Related]  

  • 7. De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation.
    Chung I; Leonhardt H; Rippe K
    J Cell Sci; 2011 Nov; 124(Pt 21):3603-18. PubMed ID: 22045732
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.
    Ambrosini G; Sambol EB; Carvajal D; Vassilev LT; Singer S; Schwartz GK
    Oncogene; 2007 May; 26(24):3473-81. PubMed ID: 17146434
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination.
    Draskovic I; Arnoult N; Steiner V; Bacchetti S; Lomonte P; Londoño-Vallejo A
    Proc Natl Acad Sci U S A; 2009 Sep; 106(37):15726-31. PubMed ID: 19717459
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PML NBs associate with the hMre11 complex and p53 at sites of irradiation induced DNA damage.
    Carbone R; Pearson M; Minucci S; Pelicci PG
    Oncogene; 2002 Mar; 21(11):1633-40. PubMed ID: 11896594
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma.
    Drakos E; Thomaides A; Medeiros LJ; Li J; Leventaki V; Konopleva M; Andreeff M; Rassidakis GZ
    Clin Cancer Res; 2007 Jun; 13(11):3380-7. PubMed ID: 17545546
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Persistent p21 expression after Nutlin-3a removal is associated with senescence-like arrest in 4N cells.
    Shen H; Maki CG
    J Biol Chem; 2010 Jul; 285(30):23105-14. PubMed ID: 20489208
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lack of TRF2 in ALT cells causes PML-dependent p53 activation and loss of telomeric DNA.
    Stagno D'Alcontres M; Mendez-Bermudez A; Foxon JL; Royle NJ; Salomoni P
    J Cell Biol; 2007 Dec; 179(5):855-67. PubMed ID: 18056407
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).
    Drakos E; Singh RR; Rassidakis GZ; Schlette E; Li J; Claret FX; Ford RJ; Vega F; Medeiros LJ
    Leukemia; 2011 May; 25(5):856-67. PubMed ID: 21394100
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transient nutlin-3a treatment promotes endoreduplication and the generation of therapy-resistant tetraploid cells.
    Shen H; Moran DM; Maki CG
    Cancer Res; 2008 Oct; 68(20):8260-8. PubMed ID: 18922897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells.
    Kojima K; Konopleva M; Samudio IJ; Ruvolo V; Andreeff M
    Cancer Res; 2007 Apr; 67(7):3210-9. PubMed ID: 17409429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of lung p53 by Nutlin-3a prevents and reverses experimental pulmonary hypertension.
    Mouraret N; Marcos E; Abid S; Gary-Bobo G; Saker M; Houssaini A; Dubois-Rande JL; Boyer L; Boczkowski J; Derumeaux G; Amsellem V; Adnot S
    Circulation; 2013 Apr; 127(16):1664-76. PubMed ID: 23513067
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential regulation of p21 (waf1) protein half-life by DNA damage and Nutlin-3 in p53 wild-type tumors and its therapeutic implications.
    Chang LJ; Eastman A
    Cancer Biol Ther; 2012 Sep; 13(11):1047-57. PubMed ID: 22825333
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nutlin-3a: A Potential Therapeutic Opportunity for TP53 Wild-Type Ovarian Carcinomas.
    Crane EK; Kwan SY; Izaguirre DI; Tsang YT; Mullany LK; Zu Z; Richards JS; Gershenson DM; Wong KK
    PLoS One; 2015; 10(8):e0135101. PubMed ID: 26248031
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiforme.
    Villalonga-Planells R; Coll-Mulet L; Martínez-Soler F; Castaño E; Acebes JJ; Giménez-Bonafé P; Gil J; Tortosa A
    PLoS One; 2011 Apr; 6(4):e18588. PubMed ID: 21483692
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.