These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 20807504)

  • 1. Potent in vivo suppression of inflammation by selectively targeting the high affinity conformation of integrin α4β1.
    Vanderslice P; Woodside DG; Caivano AR; Decker ER; Munsch CL; Sherwood SJ; Lejeune WS; Miyamoto YJ; McIntyre BW; Tilton RG; Dixon RA
    Biochem Biophys Res Commun; 2010 Oct; 400(4):619-24. PubMed ID: 20807504
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of eosinophilia in vivo by a small molecule inhibitor of very late antigen (VLA)-4.
    Okigami H; Takeshita K; Tajimi M; Komura H; Albers M; Lehmann TE; Rölle T; Bacon KB
    Eur J Pharmacol; 2007 Mar; 559(2-3):202-9. PubMed ID: 17234179
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A small molecule alpha4beta1/alpha4beta7 antagonist differentiates between the low-affinity states of alpha4beta1 and alpha4beta7: characterization of divalent cation dependence.
    Egger LA; Cao J; McCallum C; Kidambi U; Van Riper G; McCauley E; Mumford RA; Lanza TJ; Lin LS; de Laszlo SE; Young DN; Yang G; Dean DC; Raab CE; Wallace MA; Jones AN; Hagmann WK; Schmidt JA; Pepinsky RB; Scott DM; Lee WC; Cornebise MA; Detmers PA
    J Pharmacol Exp Ther; 2003 Sep; 306(3):903-13. PubMed ID: 12766251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of ligand-induced and ligand-attenuated epitopes on the leukocyte integrin alpha4beta1: VCAM-1, mucosal addressin cell adhesion molecule-1, and fibronectin induce distinct conformational changes.
    Newham P; Craig SE; Clark K; Mould AP; Humphries MJ
    J Immunol; 1998 May; 160(9):4508-17. PubMed ID: 9574557
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alpha4beta1-integrin activation is necessary for high-efficiency T-cell subset interactions with VCAM-1 under flow.
    Lim YC; Wakelin MW; Henault L; Goetz DJ; Yednock T; Cabañas C; Sánchez-Madrid F; Lichtman AH; Luscinskas FW
    Microcirculation; 2000 Jun; 7(3):201-14. PubMed ID: 10901499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale.
    Rice GP; Hartung HP; Calabresi PA
    Neurology; 2005 Apr; 64(8):1336-42. PubMed ID: 15851719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses.
    Lin Kc; Ateeq HS; Hsiung SH; Chong LT; Zimmerman CN; Castro A; Lee WC; Hammond CE; Kalkunte S; Chen LL; Pepinsky RB; Leone DR; Sprague AG; Abraham WM; Gill A; Lobb RR; Adams SP
    J Med Chem; 1999 Mar; 42(5):920-34. PubMed ID: 10072689
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin.
    Engelhardt B; Laschinger M; Schulz M; Samulowitz U; Vestweber D; Hoch G
    J Clin Invest; 1998 Dec; 102(12):2096-105. PubMed ID: 9854045
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CD14 is a ligand for the integrin alpha4beta1.
    Humphries JD; Humphries MJ
    FEBS Lett; 2007 Feb; 581(4):757-63. PubMed ID: 17274987
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and analysis of a polyethelene glycol-modified (PEGylated) small molecule inhibitor of integrin {alpha}4{beta}1 with improved pharmaceutical properties.
    Pepinsky RB; Lee WC; Cornebise M; Gill A; Wortham K; Chen LL; Leone DR; Giza K; Dolinski BM; Perper S; Nickerson-Nutter C; Lepage D; Chakraborty A; Whalley ET; Petter RC; Adams SP; Lobb RR; Scott DM
    J Pharmacol Exp Ther; 2005 Feb; 312(2):742-50. PubMed ID: 15485895
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High affinity very late antigen-4 subsets expressed on T cells are mandatory for spontaneous adhesion strengthening but not for rolling on VCAM-1 in shear flow.
    Chen C; Mobley JL; Dwir O; Shimron F; Grabovsky V; Lobb RR; Shimizu Y; Alon R
    J Immunol; 1999 Jan; 162(2):1084-95. PubMed ID: 9916737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site.
    Weitz-Schmidt G; Welzenbach K; Brinkmann V; Kamata T; Kallen J; Bruns C; Cottens S; Takada Y; Hommel U
    Nat Med; 2001 Jun; 7(6):687-92. PubMed ID: 11385505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of the very late adhesion molecule 4 antagonist WAY103 on human peripheral blood eosinophil vascular cell adhesion molecule 1-dependent functions.
    Sedgwick JB; Jansen KJ; Kennedy JD; Kita H; Busse WW
    J Allergy Clin Immunol; 2005 Oct; 116(4):812-9. PubMed ID: 16210055
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interference of nonsteroidal antiinflammatory drugs with very late activation antigen 4/vascular cells adhesion molecule 1-mediated lymphocyte-endothelial cell adhesion.
    González-Alvaro I; Muñoz C; García-Vicuña R; Sabando P; Cabañas C; Sánchez-Madrid F; Díaz-González F
    Arthritis Rheum; 1998 Sep; 41(9):1677-88. PubMed ID: 9751102
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Administration of a peptide inhibitor of alpha4-integrin inhibits the development of experimental autoimmune uveitis.
    Martín AP; de Moraes LV; Tadokoro CE; Commodaro AG; Urrets-Zavalia E; Rabinovich GA; Urrets-Zavalia J; Rizzo LV; Serra HM
    Invest Ophthalmol Vis Sci; 2005 Jun; 46(6):2056-63. PubMed ID: 15914623
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cross talk between alpha(v)beta3 and alpha4beta1 integrins regulates lymphocyte migration on vascular cell adhesion molecule 1.
    Imhof BA; Weerasinghe D; Brown EJ; Lindberg FP; Hammel P; Piali L; Dessing M; Gisler R
    Eur J Immunol; 1997 Dec; 27(12):3242-52. PubMed ID: 9464812
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of human T lymphocyte coactivation with an alpha4 integrin antagonist peptide.
    McIntyre BW; Woodside DG; Caruso DA; Wooten DK; Simon SI; Neelamegham S; Revelle JK; Vanderslice P
    J Immunol; 1997 May; 158(9):4180-6. PubMed ID: 9126978
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pulmonary eosinophilia in a murine model of allergic inflammation is attenuated by small molecule alpha4beta1 antagonists.
    Kudlacz E; Whitney C; Andresen C; Duplantier A; Beckius G; Chupak L; Klein A; Kraus K; Milici A
    J Pharmacol Exp Ther; 2002 May; 301(2):747-52. PubMed ID: 11961081
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation pathways of alpha4beta1 integrin leading to distinct T-cell cytoskeleton reorganization, Rac1 regulation and Pyk2 phosphorylation.
    Maqueda A; Moyano JV; Gutiérrez-López MD; Ovalle S; Rodríguez-Frade JM; Cabañas C; Garcia-Pardo A
    J Cell Physiol; 2006 Jun; 207(3):746-56. PubMed ID: 16514607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and assay of retro-α4β1 integrin-targeting motifs.
    Dattoli SD; De Marco R; Baiula M; Spampinato S; Greco A; Tolomelli A; Gentilucci L
    Eur J Med Chem; 2014 Feb; 73():225-32. PubMed ID: 24412498
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.