335 related articles for article (PubMed ID: 20807782)
1. Molecular therapy targeting Sonic hedgehog and hepatocyte growth factor signaling in a mouse model of medulloblastoma.
Coon V; Laukert T; Pedone CA; Laterra J; Kim KJ; Fults DW
Mol Cancer Ther; 2010 Sep; 9(9):2627-36. PubMed ID: 20807782
[TBL] [Abstract][Full Text] [Related]
2. Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth.
Binning MJ; Niazi T; Pedone CA; Lal B; Eberhart CG; Kim KJ; Laterra J; Fults DW
Cancer Res; 2008 Oct; 68(19):7838-45. PubMed ID: 18829539
[TBL] [Abstract][Full Text] [Related]
3. Apoptosis suppression by somatic cell transfer of Bcl-2 promotes Sonic hedgehog-dependent medulloblastoma formation in mice.
McCall TD; Pedone CA; Fults DW
Cancer Res; 2007 Jun; 67(11):5179-85. PubMed ID: 17545597
[TBL] [Abstract][Full Text] [Related]
4. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.
Northcott PA; Fernandez-L A; Hagan JP; Ellison DW; Grajkowska W; Gillespie Y; Grundy R; Van Meter T; Rutka JT; Croce CM; Kenney AM; Taylor MD
Cancer Res; 2009 Apr; 69(8):3249-55. PubMed ID: 19351822
[TBL] [Abstract][Full Text] [Related]
5. Targeting sonic hedgehog-associated medulloblastoma through inhibition of Aurora and Polo-like kinases.
Markant SL; Esparza LA; Sun J; Barton KL; McCoig LM; Grant GA; Crawford JR; Levy ML; Northcott PA; Shih D; Remke M; Taylor MD; Wechsler-Reya RJ
Cancer Res; 2013 Oct; 73(20):6310-22. PubMed ID: 24067506
[TBL] [Abstract][Full Text] [Related]
6. Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells.
Elamin MH; Shinwari Z; Hendrayani SF; Al-Hindi H; Al-Shail E; Khafaga Y; Al-Kofide A; Aboussekhra A
Mol Carcinog; 2010 Mar; 49(3):302-14. PubMed ID: 20025076
[TBL] [Abstract][Full Text] [Related]
7. scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.
Ocasio JK; Babcock B; Malawsky D; Weir SJ; Loo L; Simon JM; Zylka MJ; Hwang D; Dismuke T; Sokolsky M; Rosen EP; Vibhakar R; Zhang J; Saulnier O; Vladoiu M; El-Hamamy I; Stein LD; Taylor MD; Smith KS; Northcott PA; Colaneri A; Wilhelmsen K; Gershon TR
Nat Commun; 2019 Dec; 10(1):5829. PubMed ID: 31863004
[TBL] [Abstract][Full Text] [Related]
8. A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
Conduit SE; Ramaswamy V; Remke M; Watkins DN; Wainwright BJ; Taylor MD; Mitchell CA; Dyson JM
Oncogene; 2017 Oct; 36(43):5969-5984. PubMed ID: 28650469
[TBL] [Abstract][Full Text] [Related]
9. Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis.
Stabile LP; Rothstein ME; Keohavong P; Jin J; Yin J; Land SR; Dacic S; Luong TM; Kim KJ; Dulak AM; Siegfried JM
Mol Cancer Ther; 2008 Jul; 7(7):1913-22. PubMed ID: 18645002
[TBL] [Abstract][Full Text] [Related]
10. Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
Faria CC; Golbourn BJ; Dubuc AM; Remke M; Diaz RJ; Agnihotri S; Luck A; Sabha N; Olsen S; Wu X; Garzia L; Ramaswamy V; Mack SC; Wang X; Leadley M; Reynaud D; Ermini L; Post M; Northcott PA; Pfister SM; Croul SE; Kool M; Korshunov A; Smith CA; Taylor MD; Rutka JT
Cancer Res; 2015 Jan; 75(1):134-46. PubMed ID: 25391241
[TBL] [Abstract][Full Text] [Related]
11. Sonic Hedgehog inhibition as a strategy to augment radiosensitivity of hepatocellular carcinoma.
Tsai CL; Hsu FM; Tzen KY; Liu WL; Cheng AL; Cheng JC
J Gastroenterol Hepatol; 2015 Aug; 30(8):1317-24. PubMed ID: 25682950
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.
Rodriguez-Blanco J; Pednekar L; Penas C; Li B; Martin V; Long J; Lee E; Weiss WA; Rodriguez C; Mehrdad N; Nguyen DM; Ayad NG; Rai P; Capobianco AJ; Robbins DJ
Oncogene; 2017 Nov; 36(45):6306-6314. PubMed ID: 28714964
[TBL] [Abstract][Full Text] [Related]
13. Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma.
Heine VM; Priller M; Ling J; Rowitch DH; Schüller U
Cancer Res; 2010 Jul; 70(13):5220-5. PubMed ID: 20530674
[TBL] [Abstract][Full Text] [Related]
14. Inhibitory potential of postnatal treatment with cyclopamine, a hedgehog signaling inhibitor, on medulloblastoma development in Ptch1 heterozygous mice.
Matsuo S; Takahashi M; Inoue K; Tamura K; Irie K; Kodama Y; Nishikawa A; Yoshida M
Toxicol Pathol; 2014 Dec; 42(8):1174-87. PubMed ID: 24862798
[TBL] [Abstract][Full Text] [Related]
15. YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.
Fernandez-L A; Northcott PA; Dalton J; Fraga C; Ellison D; Angers S; Taylor MD; Kenney AM
Genes Dev; 2009 Dec; 23(23):2729-41. PubMed ID: 19952108
[TBL] [Abstract][Full Text] [Related]
16. p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.
Wei Y; Maximov V; Morrissy SA; Taylor MD; Pallas DC; Kenney AM
Mol Cancer Res; 2019 Jan; 17(1):186-198. PubMed ID: 30224541
[TBL] [Abstract][Full Text] [Related]
17. YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
Dey A; Robitaille M; Remke M; Maier C; Malhotra A; Gregorieff A; Wrana JL; Taylor MD; Angers S; Kenney AM
Oncogene; 2016 Aug; 35(32):4256-68. PubMed ID: 26725322
[TBL] [Abstract][Full Text] [Related]
18. Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts.
Kim KJ; Wang L; Su YC; Gillespie GY; Salhotra A; Lal B; Laterra J
Clin Cancer Res; 2006 Feb; 12(4):1292-8. PubMed ID: 16489086
[TBL] [Abstract][Full Text] [Related]
19. WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.
Doucette TA; Yang Y; Pedone C; Kim JY; Dubuc A; Northcott PD; Taylor MD; Fults DW; Rao G
Neurosurgery; 2012 Apr; 70(4):1003-10; discussion 1010. PubMed ID: 22037313
[TBL] [Abstract][Full Text] [Related]
20. An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.
Wijaya J; Vo BT; Liu J; Xu B; Wu G; Wang Y; Peng J; Zhang J; Janke LJ; Orr BA; Yu J; Roussel MF; Schuetz JD
Cancer Res; 2020 Apr; 80(7):1524-1537. PubMed ID: 31948942
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]