BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 20808849)

  • 1. Variations in TcdB activity and the hypervirulence of emerging strains of Clostridium difficile.
    Lanis JM; Barua S; Ballard JD
    PLoS Pathog; 2010 Aug; 6(8):e1001061. PubMed ID: 20808849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TcdB from hypervirulent Clostridium difficile exhibits increased efficiency of autoprocessing.
    Lanis JM; Hightower LD; Shen A; Ballard JD
    Mol Microbiol; 2012 Apr; 84(1):66-76. PubMed ID: 22372854
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intrinsic Toxin-Derived Peptides Destabilize and Inactivate
    Larabee JL; Bland SJ; Hunt JJ; Ballard JD
    mBio; 2017 May; 8(3):. PubMed ID: 28512094
    [No Abstract]   [Full Text] [Related]  

  • 4. Human hypervirulent Clostridium difficile strains exhibit increased sporulation as well as robust toxin production.
    Merrigan M; Venugopal A; Mallozzi M; Roxas B; Viswanathan VK; Johnson S; Gerding DN; Vedantam G
    J Bacteriol; 2010 Oct; 192(19):4904-11. PubMed ID: 20675495
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities.
    Quesada-Gómez C; López-Ureña D; Chumbler N; Kroh HK; Castro-Peña C; Rodríguez C; Orozco-Aguilar J; González-Camacho S; Rucavado A; Guzmán-Verri C; Lawley TD; Lacy DB; Chaves-Olarte E
    Infect Immun; 2016 Jan; 84(3):856-65. PubMed ID: 26755157
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences.
    Stabler RA; Dawson LF; Phua LTH; Wren BW
    J Med Microbiol; 2008 Jun; 57(Pt 6):771-775. PubMed ID: 18480336
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of an Essential Region for Translocation of Clostridium difficile Toxin B.
    Chen S; Wang H; Gu H; Sun C; Li S; Feng H; Wang J
    Toxins (Basel); 2016 Aug; 8(8):. PubMed ID: 27537911
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional defects in
    Gupta P; Zhang Z; Sugiman-Marangos SN; Tam J; Raman S; Julien JP; Kroh HK; Lacy DB; Murgolo N; Bekkari K; Therien AG; Hernandez LD; Melnyk RA
    J Biol Chem; 2017 Oct; 292(42):17290-17301. PubMed ID: 28842504
    [No Abstract]   [Full Text] [Related]  

  • 9. Toward a structural understanding of Clostridium difficile toxins A and B.
    Pruitt RN; Lacy DB
    Front Cell Infect Microbiol; 2012; 2():28. PubMed ID: 22919620
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Variations in virulence and molecular biology among emerging strains of Clostridium difficile.
    Hunt JJ; Ballard JD
    Microbiol Mol Biol Rev; 2013 Dec; 77(4):567-81. PubMed ID: 24296572
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B.
    Mansfield MJ; Tremblay BJ; Zeng J; Wei X; Hodgins H; Worley J; Bry L; Dong M; Doxey AC
    PLoS Pathog; 2020 Dec; 16(12):e1009181. PubMed ID: 33370413
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Receptor Binding Domains of TcdB from
    Henkel D; Tatge H; Schöttelndreier D; Tao L; Dong M; Gerhard R
    Toxins (Basel); 2020 Nov; 12(12):. PubMed ID: 33255261
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Toxin B is essential for virulence of Clostridium difficile.
    Lyras D; O'Connor JR; Howarth PM; Sambol SP; Carter GP; Phumoonna T; Poon R; Adams V; Vedantam G; Johnson S; Gerding DN; Rood JI
    Nature; 2009 Apr; 458(7242):1176-9. PubMed ID: 19252482
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hype or hypervirulence: a reflection on problematic C. difficile strains.
    Smits WK
    Virulence; 2013 Oct; 4(7):592-6. PubMed ID: 24060961
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells.
    Rupnik M; Pabst S; Rupnik M; von Eichel-Streiber C; Urlaub H; Söling HD
    Microbiology (Reading); 2005 Jan; 151(Pt 1):199-208. PubMed ID: 15632438
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis for recognition of frizzled proteins by
    Chen P; Tao L; Wang T; Zhang J; He A; Lam KH; Liu Z; He X; Perry K; Dong M; Jin R
    Science; 2018 May; 360(6389):664-669. PubMed ID: 29748286
    [No Abstract]   [Full Text] [Related]  

  • 17. Exposure of neutralizing epitopes in the carboxyl-terminal domain of TcdB is altered by a proximal hypervariable region.
    Larabee JL; Krumholz A; Hunt JJ; Lanis JM; Ballard JD
    J Biol Chem; 2015 Mar; 290(11):6975-85. PubMed ID: 25614625
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Subtyping analysis reveals new variants and accelerated evolution of Clostridioides difficile toxin B.
    Shen E; Zhu K; Li D; Pan Z; Luo Y; Bian Q; He L; Song X; Zhen Y; Jin D; Tao L
    Commun Biol; 2020 Jul; 3(1):347. PubMed ID: 32620855
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of the role of toxin B in the virulence of Clostridioides difficile based on integrated bioinformatics analyses.
    Gao Y; Gao W; Cheng J; Ma L; Su J
    Int Microbiol; 2020 Nov; 23(4):575-587. PubMed ID: 32388701
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A neutralizing antibody that blocks delivery of the enzymatic cargo of
    Kroh HK; Chandrasekaran R; Zhang Z; Rosenthal K; Woods R; Jin X; Nyborg AC; Rainey GJ; Warrener P; Melnyk RA; Spiller BW; Lacy DB
    J Biol Chem; 2018 Jan; 293(3):941-952. PubMed ID: 29180448
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 14.