BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 20810355)

  • 1. Cadmium alters the biotransformation of carcinogenic aromatic amines by arylamine N-acetyltransferase xenobiotic-metabolizing enzymes: molecular, cellular, and in vivo studies.
    Ragunathan N; Dairou J; Sanfins E; Busi F; Noll C; Janel N; Dupret JM; Rodrigues-Lima F
    Environ Health Perspect; 2010 Dec; 118(12):1685-91. PubMed ID: 20810355
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of cancer chemopreventive isothiocyanates as direct inhibitors of the arylamine N-acetyltransferase-dependent acetylation and bioactivation of aromatic amine carcinogens.
    Duval R; Xu X; Bui LC; Mathieu C; Petit E; Cariou K; Dodd RH; Dupret JM; Rodrigues-Lima F
    Oncotarget; 2016 Feb; 7(8):8688-99. PubMed ID: 26840026
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo and in vitro metabolism of arylamine procarcinogens in acetyltransferase-deficient mice.
    Sugamori KS; Brenneman D; Grant DM
    Drug Metab Dispos; 2006 Oct; 34(10):1697-702. PubMed ID: 16815960
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines.
    Liu L; Wagner CR; Hanna PE
    Chem Res Toxicol; 2009 Dec; 22(12):1962-74. PubMed ID: 19842618
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arylamine N-acetyltransferase activity in bronchial epithelial cells and its inhibition by cellular oxidants.
    Dairou J; Petit E; Ragunathan N; Baeza-Squiban A; Marano F; Dupret JM; Rodrigues-Lima F
    Toxicol Appl Pharmacol; 2009 May; 236(3):366-71. PubMed ID: 19248797
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
    Hein DW; Doll MA; Rustan TD; Gray K; Feng Y; Ferguson RJ; Grant DM
    Carcinogenesis; 1993 Aug; 14(8):1633-8. PubMed ID: 8353847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of environmental substances on the activity of arylamine N-acetyltransferases.
    Rodrigues-Lima F; Dairou J; Dupret JM
    Curr Drug Metab; 2008 Jul; 9(6):505-9. PubMed ID: 18680470
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of the xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 as a new target of cisplatin in breast cancer cells: molecular and cellular mechanisms of inhibition.
    Ragunathan N; Dairou J; Pluvinage B; Martins M; Petit E; Janel N; Dupret JM; Rodrigues-Lima F
    Mol Pharmacol; 2008 Jun; 73(6):1761-8. PubMed ID: 18310302
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Peroxynitrite irreversibly inactivates the human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) in human breast cancer cells: a cellular and mechanistic study.
    Dairou J; Atmane N; Rodrigues-Lima F; Dupret JM
    J Biol Chem; 2004 Feb; 279(9):7708-14. PubMed ID: 14672957
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) is irreversibly inhibited by inorganic (Hg2+) and organic mercury (CH3Hg+): mechanism and kinetics.
    Ragunathan N; Busi F; Pluvinage B; Sanfins E; Dupret JM; Rodrigues-Lima F; Dairou J
    FEBS Lett; 2010 Aug; 584(15):3366-9. PubMed ID: 20591428
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human arylamine N-acetyltransferase 1: in vitro and intracellular inactivation by nitrosoarene metabolites of toxic and carcinogenic arylamines.
    Liu L; Wagner CR; Hanna PE
    Chem Res Toxicol; 2008 Oct; 21(10):2005-16. PubMed ID: 18759501
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase.
    Hein DW; Flammang TJ; Kirlin WG; Trinidad A; Ogolla F
    Carcinogenesis; 1987 Dec; 8(12):1767-74. PubMed ID: 3677303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. From arylamine N-acetyltransferase to folate-dependent acetyl CoA hydrolase: impact of folic acid on the activity of (HUMAN)NAT1 and its homologue (MOUSE)NAT2.
    Laurieri N; Dairou J; Egleton JE; Stanley LA; Russell AJ; Dupret JM; Sim E; Rodrigues-Lima F
    PLoS One; 2014; 9(5):e96370. PubMed ID: 24823794
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide.
    Atmane N; Dairou J; Paul A; Dupret JM; Rodrigues-Lima F
    J Biol Chem; 2003 Sep; 278(37):35086-92. PubMed ID: 12832400
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The xenobiotic-metabolizing enzymes arylamine N-acetyltransferases in human lens epithelial cells: inactivation by cellular oxidants and UVB-induced oxidative stress.
    Dairou J; Malecaze F; Dupret JM; Rodrigues-Lima F
    Mol Pharmacol; 2005 Apr; 67(4):1299-306. PubMed ID: 15644493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human arylamine N-acetyltransferase 1: a drug-metabolizing enzyme and a drug target?
    Rodrigues-Lima F; Dairou J; Busi F; Dupret JM
    Curr Drug Targets; 2010 Jun; 11(6):759-66. PubMed ID: 20041842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hexavalent chromium increases the metabolism and genotoxicity of aromatic amine carcinogens 4-aminobiphenyl and β-naphthylamine in immortalized human lung epithelial cells.
    Wise JTF; Salazar-González RA; Walls KM; Doll MA; Habil MR; Hein DW
    Toxicol Appl Pharmacol; 2022 Aug; 449():116095. PubMed ID: 35662664
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure and regulation of the drug-metabolizing enzymes arylamine N-acetyltransferases.
    Dupret JM; Rodrigues-Lima F
    Curr Med Chem; 2005; 12(3):311-8. PubMed ID: 15723621
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding.
    Laurieri N; Kawamura A; Westwood IM; Varney A; Morris E; Russell AJ; Stanley LA; Sim E
    BMC Pharmacol Toxicol; 2014 Nov; 15():68. PubMed ID: 25432241
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioactivation of N-arylhydroxamic acids by rat hepatic N-acetyltransferase. Detection of multiple enzyme forms by mechanism-based inactivation.
    Wick MJ; Hanna PE
    Biochem Pharmacol; 1990 Mar; 39(6):991-1003. PubMed ID: 2322300
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.