BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 20813865)

  • 21. WNK bodies cluster WNK4 and SPAK/OSR1 to promote NCC activation in hypokalemia.
    Thomson MN; Cuevas CA; Bewarder TM; Dittmayer C; Miller LN; Si J; Cornelius RJ; Su XT; Yang CL; McCormick JA; Hadchouel J; Ellison DH; Bachmann S; Mutig K
    Am J Physiol Renal Physiol; 2020 Jan; 318(1):F216-F228. PubMed ID: 31736353
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Molecular insights from dysregulation of the thiazide-sensitive WNK/SPAK/NCC pathway in the kidney: Gordon syndrome and thiazide-induced hyponatraemia.
    Glover M; O'Shaughnessy KM
    Clin Exp Pharmacol Physiol; 2013 Dec; 40(12):876-84. PubMed ID: 23683032
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1.
    Richardson C; Rafiqi FH; Karlsson HK; Moleleki N; Vandewalle A; Campbell DG; Morrice NA; Alessi DR
    J Cell Sci; 2008 Mar; 121(Pt 5):675-84. PubMed ID: 18270262
    [TBL] [Abstract][Full Text] [Related]  

  • 24. A SPAK isoform switch modulates renal salt transport and blood pressure.
    McCormick JA; Mutig K; Nelson JH; Saritas T; Hoorn EJ; Yang CL; Rogers S; Curry J; Delpire E; Bachmann S; Ellison DH
    Cell Metab; 2011 Sep; 14(3):352-64. PubMed ID: 21907141
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.
    Davies M; Fraser SA; Galic S; Choy SW; Katerelos M; Gleich K; Kemp BE; Mount PF; Power DA
    Am J Physiol Renal Physiol; 2014 Jul; 307(1):F96-F106. PubMed ID: 24808538
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.
    Richardson C; Sakamoto K; de los Heros P; Deak M; Campbell DG; Prescott AR; Alessi DR
    J Cell Sci; 2011 Mar; 124(Pt 5):789-800. PubMed ID: 21321328
    [TBL] [Abstract][Full Text] [Related]  

  • 27. WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.
    Moriguchi T; Urushiyama S; Hisamoto N; Iemura S; Uchida S; Natsume T; Matsumoto K; Shibuya H
    J Biol Chem; 2005 Dec; 280(52):42685-93. PubMed ID: 16263722
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Phosphorylation regulates NCC stability and transporter activity in vivo.
    Yang SS; Fang YW; Tseng MH; Chu PY; Yu IS; Wu HC; Lin SW; Chau T; Uchida S; Sasaki S; Lin YF; Sytwu HK; Lin SH
    J Am Soc Nephrol; 2013 Oct; 24(10):1587-97. PubMed ID: 23833262
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of WNK3 Kinase Signaling Reduces Brain Damage and Accelerates Neurological Recovery After Stroke.
    Begum G; Yuan H; Kahle KT; Li L; Wang S; Shi Y; Shmukler BE; Yang SS; Lin SH; Alper SL; Sun D
    Stroke; 2015 Jul; 46(7):1956-1965. PubMed ID: 26069258
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters.
    de Los Heros P; Alessi DR; Gourlay R; Campbell DG; Deak M; Macartney TJ; Kahle KT; Zhang J
    Biochem J; 2014 Mar; 458(3):559-73. PubMed ID: 24393035
    [TBL] [Abstract][Full Text] [Related]  

  • 31. WNK signalling pathways in blood pressure regulation.
    Murthy M; Kurz T; O'Shaughnessy KM
    Cell Mol Life Sci; 2017 Apr; 74(7):1261-1280. PubMed ID: 27815594
    [TBL] [Abstract][Full Text] [Related]  

  • 32. On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity.
    Gagnon KB; Delpire E
    Am J Physiol Cell Physiol; 2010 Sep; 299(3):C614-20. PubMed ID: 20463172
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Suppression of WNK1-SPAK/OSR1 Attenuates Bone Cancer Pain by Regulating NKCC1 and KCC2.
    Gao JL; Peng K; Shen MW; Hou YH; Qian XB; Meng XW; Ji FH; Wang LN; Yang JP
    J Pain; 2019 Dec; 20(12):1416-1428. PubMed ID: 31085334
    [TBL] [Abstract][Full Text] [Related]  

  • 34. WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
    Susa K; Sohara E; Takahashi D; Okado T; Rai T; Uchida S
    Biochem Biophys Res Commun; 2017 Sep; 491(3):727-732. PubMed ID: 28743496
    [TBL] [Abstract][Full Text] [Related]  

  • 35. STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy.
    Yang L; Cai X; Zhou J; Chen S; Chen Y; Chen Z; Wang Q; Fang Z; Zhou L
    PLoS One; 2013; 8(9):e74614. PubMed ID: 24058604
    [TBL] [Abstract][Full Text] [Related]  

  • 36. NF-κB Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice.
    Bhuiyan MIH; Young CB; Jahan I; Hasan MN; Fischer S; Meor Azlan NF; Liu M; Chattopadhyay A; Huang H; Kahle KT; Zhang J; Poloyac SM; Molyneaux BJ; Straub AC; Deng X; Gomez D; Sun D
    Stroke; 2022 May; 53(5):1720-1734. PubMed ID: 35272484
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2.
    Park HJ; Curry JN; McCormick JA
    Am J Physiol Renal Physiol; 2013 Dec; 305(12):F1687-96. PubMed ID: 24133122
    [TBL] [Abstract][Full Text] [Related]  

  • 38. WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family.
    Pacheco-Alvarez D; Vázquez N; Castañeda-Bueno M; de-Los-Heros P; Cortes-González C; Moreno E; Meade P; Bobadilla NA; Gamba G
    Cell Physiol Biochem; 2012; 29(1-2):291-302. PubMed ID: 22415098
    [TBL] [Abstract][Full Text] [Related]  

  • 39. OSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis.
    Liu YL; Yang SS; Chen SJ; Lin YC; Chu CC; Huang HH; Chang FW; Yu MH; Lin SH; Wu GJ; Sytwu HK
    Sci Rep; 2016 Nov; 6():37205. PubMed ID: 27853306
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Targeting the WNK-SPAK/OSR1 Pathway and Cation-Chloride Cotransporters for the Therapy of Stroke.
    Josiah SS; Meor Azlan NF; Zhang J
    Int J Mol Sci; 2021 Jan; 22(3):. PubMed ID: 33513812
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.