Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 20818428)

  • 1. β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.
    Ahmad I; Morton JP; Singh LB; Radulescu SM; Ridgway RA; Patel S; Woodgett J; Winton DJ; Taketo MM; Wu XR; Leung HY; Sansom OJ
    Oncogene; 2011 Jan; 30(2):178-89. PubMed ID: 20818428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
    Jefferies MT; Cox AC; Shorning BY; Meniel V; Griffiths D; Kynaston HG; Smalley MJ; Clarke AR
    J Pathol; 2017 Dec; 243(4):442-456. PubMed ID: 29134654
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PI3K/AKT pathway activation in bladder carcinogenesis.
    Calderaro J; Rebouissou S; de Koning L; Masmoudi A; Hérault A; Dubois T; Maille P; Soyeux P; Sibony M; de la Taille A; Vordos D; Lebret T; Radvanyi F; Allory Y
    Int J Cancer; 2014 Apr; 134(8):1776-84. PubMed ID: 24122582
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice.
    Foth M; Ahmad I; van Rhijn BW; van der Kwast T; Bergman AM; King L; Ridgway R; Leung HY; Fraser S; Sansom OJ; Iwata T
    J Pathol; 2014 Jun; 233(2):148-58. PubMed ID: 24519156
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN.
    Tanwar PS; Zhang L; Kaneko-Tarui T; Curley MD; Taketo MM; Rani P; Roberts DJ; Teixeira JM
    PLoS One; 2011; 6(6):e20715. PubMed ID: 21695255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis.
    Ahmad I; Patel R; Liu Y; Singh LB; Taketo MM; Wu XR; Leung HY; Sansom OJ
    Cell Death Dis; 2011 Mar; 2(3):e124. PubMed ID: 21368895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models.
    Qian CN; Furge KA; Knol J; Huang D; Chen J; Dykema KJ; Kort EJ; Massie A; Khoo SK; Vanden Beldt K; Resau JH; Anema J; Kahnoski RJ; Morreau H; Camparo P; Comperat E; Sibony M; Denoux Y; Molinie V; Vieillefond A; Eng C; Williams BO; Teh BT
    Cancer Res; 2009 Nov; 69(21):8256-64. PubMed ID: 19843858
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis.
    Zhao H; Cui Y; Dupont J; Sun H; Hennighausen L; Yakar S
    Cancer Res; 2005 Aug; 65(15):6864-73. PubMed ID: 16061670
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activation.
    Seront E; Pinto A; Bouzin C; Bertrand L; Machiels JP; Feron O
    Br J Cancer; 2013 Sep; 109(6):1586-92. PubMed ID: 23989949
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intestinal epithelial-specific PTEN inactivation results in tumor formation.
    Byun DS; Ahmed N; Nasser S; Shin J; Al-Obaidi S; Goel S; Corner GA; Wilson AJ; Flanagan DJ; Williams DS; Augenlicht LH; Vincan E; Mariadason JM
    Am J Physiol Gastrointest Liver Physiol; 2011 Nov; 301(5):G856-64. PubMed ID: 21836055
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alpha1-ACT Functions as a Tumour Suppressor in Hepatocellular Carcinoma by Inhibiting the PI3K/AKT/mTOR Signalling Pathway via Activation of PTEN.
    Zhu H; Liu Q; Tang J; Xie Y; Xu X; Huang R; Zhang Y; Jin K; Sun B
    Cell Physiol Biochem; 2017; 41(6):2289-2306. PubMed ID: 28456796
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oncogenic mutations in adenomatous polyposis coli (Apc) activate mechanistic target of rapamycin complex 1 (mTORC1) in mice and zebrafish.
    Valvezan AJ; Huang J; Lengner CJ; Pack M; Klein PS
    Dis Model Mech; 2014 Jan; 7(1):63-71. PubMed ID: 24092877
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling.
    Korkaya H; Paulson A; Charafe-Jauffret E; Ginestier C; Brown M; Dutcher J; Clouthier SG; Wicha MS
    PLoS Biol; 2009 Jun; 7(6):e1000121. PubMed ID: 19492080
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prevalence of APC and PTEN Alterations in Urachal Cancer.
    Nagy N; Reis H; Hadaschik B; Niedworok C; Módos O; Szendrői A; Bíró K; Hager T; Herold T; Ablat J; Black PC; Okon K; Tolkach Y; Csizmarik A; Oláh C; Keresztes D; Bremmer F; Gaisa NT; Kriegsmann J; Kovalszky I; Kiss A; Tímár J; Szász MA; Rink M; Fisch M; Nyirády P; Szarvas T
    Pathol Oncol Res; 2020 Oct; 26(4):2773-2781. PubMed ID: 32754865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Somatic mutations of adenomatous polyposis coli gene and nuclear b-catenin accumulation have prognostic significance in invasive urothelial carcinomas: evidence for Wnt pathway implication.
    Kastritis E; Murray S; Kyriakou F; Horti M; Tamvakis N; Kavantzas N; Patsouris ES; Noni A; Legaki S; Dimopoulos MA; Bamias A
    Int J Cancer; 2009 Jan; 124(1):103-8. PubMed ID: 18844223
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.
    Perry JM; He XC; Sugimura R; Grindley JC; Haug JS; Ding S; Li L
    Genes Dev; 2011 Sep; 25(18):1928-42. PubMed ID: 21890648
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of CREB binding protein-beta-catenin signaling down regulates CD133 expression and activates PP2A-PTEN signaling in tumor initiating liver cancer cells.
    Tang Y; Berlind J; Mavila N
    Cell Commun Signal; 2018 Mar; 16(1):9. PubMed ID: 29530069
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma.
    Brait M; Munari E; LeBron C; Noordhuis MG; Begum S; Michailidi C; Gonzalez-Roibon N; Maldonado L; Sen T; Guerrero-Preston R; Cope L; Parrella P; Fazio VM; Ha PK; Netto GJ; Sidransky D; Hoque MO
    Cell Cycle; 2013 Apr; 12(7):1058-70. PubMed ID: 23435205
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GPNMB augments Wnt-1 mediated breast tumor initiation and growth by enhancing PI3K/AKT/mTOR pathway signaling and β-catenin activity.
    Maric G; Annis MG; MacDonald PA; Russo C; Perkins D; Siwak DR; Mills GB; Siegel PM
    Oncogene; 2019 Jun; 38(26):5294-5307. PubMed ID: 30914799
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation.
    Radulescu S; Ridgway RA; Cordero J; Athineos D; Salgueiro P; Poulsom R; Neumann J; Jung A; Patel S; Woodgett J; Barker N; Pritchard DM; Oien K; Sansom OJ
    Oncogene; 2013 Apr; 32(16):2048-57. PubMed ID: 22665058
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.