BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

531 related articles for article (PubMed ID: 2082193)

  • 1. Dominant negative transcriptional regulation by a mutant thyroid hormone receptor-beta in a family with generalized resistance to thyroid hormone.
    Sakurai A; Miyamoto T; Refetoff S; DeGroot LJ
    Mol Endocrinol; 1990 Dec; 4(12):1988-94. PubMed ID: 2082193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Triiodothyroacetic acid has unique potential for therapy of resistance to thyroid hormone.
    Takeda T; Suzuki S; Liu RT; DeGroot LJ
    J Clin Endocrinol Metab; 1995 Jul; 80(7):2033-40. PubMed ID: 7608251
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Variable transcriptional activity and ligand binding of mutant beta 1 3,5,3'-triiodothyronine receptors from four families with generalized resistance to thyroid hormone.
    Meier CA; Dickstein BM; Ashizawa K; McClaskey JH; Muchmore P; Ransom SC; Menke JB; Hao EH; Usala SJ; Bercu BB
    Mol Endocrinol; 1992 Feb; 6(2):248-58. PubMed ID: 1569968
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
    Zavacki AM; Harney JW; Brent GA; Larsen PR
    Mol Endocrinol; 1993 Oct; 7(10):1319-30. PubMed ID: 8264663
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Two thyroid hormone response elements are present in the promoter of human thyroid hormone receptor beta 1.
    Suzuki S; Miyamoto T; Opsahl A; Sakurai A; DeGroot LJ
    Mol Endocrinol; 1994 Mar; 8(3):305-14. PubMed ID: 8015548
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The function of retinoid X receptors on negative thyroid hormone response elements.
    Takeda T; Nagasawa T; Miyamoto T; Hashizume K; DeGroot LJ
    Mol Cell Endocrinol; 1997 Apr; 128(1-2):85-96. PubMed ID: 9140079
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of human beta 1 thyroid hormone receptor and its mutants with DNA and retinoid X receptor beta. T3 response element-dependent dominant negative potency.
    Meier CA; Parkison C; Chen A; Ashizawa K; Meier-Heusler SC; Muchmore P; Cheng SY; Weintraub BD
    J Clin Invest; 1993 Oct; 92(4):1986-93. PubMed ID: 8408652
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thyroid hormone receptor-beta mutants associated with generalized resistance to thyroid hormone show defects in their ligand-sensitive repression function.
    Piedrafita FJ; Ortiz MA; Pfahl M
    Mol Endocrinol; 1995 Nov; 9(11):1533-48. PubMed ID: 8584031
    [TBL] [Abstract][Full Text] [Related]  

  • 9. High affinity and specificity of dimeric binding of thyroid hormone receptors to DNA and their ligand-dependent dissociation.
    Miyamoto T; Suzuki S; DeGroot LJ
    Mol Endocrinol; 1993 Feb; 7(2):224-31. PubMed ID: 8469235
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Understanding the molecular mechanism of dominant negative action of mutant thyroid hormone beta 1-receptors: the important role of the wild-type/mutant receptor heterodimer.
    Zhu XG; Yu CL; McPhie P; Wong R; Cheng SY
    Endocrinology; 1996 Feb; 137(2):712-21. PubMed ID: 8593822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. N-terminal variants of thyroid hormone receptor beta: differential function and potential contribution to syndrome of resistance to thyroid hormone.
    Ng L; Forrest D; Haugen BR; Wood WM; Curran T
    Mol Endocrinol; 1995 Sep; 9(9):1202-13. PubMed ID: 7491112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Negative and positive transcriptional regulation by thyroid hormone receptor isoforms.
    Rentoumis A; Chatterjee VK; Madison LD; Datta S; Gallagher GD; Degroot LJ; Jameson JL
    Mol Endocrinol; 1990 Oct; 4(10):1522-31. PubMed ID: 2284000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amino acid substitutions of thyroid hormone receptor-beta at codon 435 with resistance to thyroid hormone selectively alter homodimer formation.
    Nomura Y; Nagaya T; Tsukaguchi H; Takamatsu J; Seo H
    Endocrinology; 1996 Oct; 137(10):4082-6. PubMed ID: 8828460
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of naturally occurring dominant negative mutants of thyroid hormone alpha 1 and beta 1 receptors in a human hepatocellular carcinoma cell line.
    Lin KH; Zhu XG; Shieh HY; Hsu HC; Chen ST; McPhie P; Cheng SY
    Endocrinology; 1996 Oct; 137(10):4073-81. PubMed ID: 8828459
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Difference in dominant negative activities between mutant thyroid hormone receptors alpha1 and beta1 with an identical truncation in the extreme carboxyl-terminal tau4 domain.
    Nishiyama K; Andoh S; Kitahara A; Natsume H; Mikami T; Genma R; Nakamura H
    Mol Cell Endocrinol; 1998 Mar; 138(1-2):95-104. PubMed ID: 9685218
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New insights on the mechanism(s) of the dominant negative effect of mutant thyroid hormone receptor in generalized resistance to thyroid hormone.
    Yen PM; Sugawara A; Refetoff S; Chin WW
    J Clin Invest; 1992 Nov; 90(5):1825-31. PubMed ID: 1430208
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dominant-negative mutant thyroid hormone receptors prevent transcription from Xenopus thyroid hormone receptor beta gene promoter in response to thyroid hormone in Xenopus tadpoles in vivo.
    Ulisse S; Esslemont G; Baker BS; Krishna V; Chatterjee K; Tata JR
    Proc Natl Acad Sci U S A; 1996 Feb; 93(3):1205-9. PubMed ID: 8577741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of thyroid hormone action by mutant thyroid hormone receptors, c-erbA alpha 2 and peroxisome proliferator-activated receptor: evidence for different mechanisms of inhibition.
    Meier-Heusler SC; Zhu X; Juge-Aubry C; Pernin A; Burger AG; Cheng SY; Meier CA
    Mol Cell Endocrinol; 1995 Jan; 107(1):55-66. PubMed ID: 7796935
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ligand (T3) dependent and independent effects of thyroid hormone receptors upon human TRH gene transcription in neuroblastoma cells.
    Feng P; Li QL; Satoh T; Wilber JF
    Biochem Biophys Res Commun; 1994 Apr; 200(1):171-7. PubMed ID: 8166684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell type-dependent modulation of the dominant negative action of human mutant thyroid hormone beta 1 receptors.
    Wong R; Zhu XG; Pineda MA; Cheng SY; Weintraub BD
    Mol Med; 1995 Mar; 1(3):306-19. PubMed ID: 8529109
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.