BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 20824708)

  • 21. Development of a single-chain fragment variable fused-mutant HALT-1 recombinant immunotoxin against G12V mutated
    Teo MYM; Ng JJC; Fong JY; Hwang JS; Song AA; Lim RLH; In LLA
    PeerJ; 2021; 9():e11063. PubMed ID: 33959410
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Generation of affinity matured scFv antibodies against mouse neural cell adhesion molecule L1 by phage display.
    Dong L; Chen S; Bartsch U; Schachner M
    Biochem Biophys Res Commun; 2003 Jan; 301(1):60-70. PubMed ID: 12535641
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Single-chain antibody-based immunotoxins targeting Her2/neu: design optimization and impact of affinity on antitumor efficacy and off-target toxicity.
    Cao Y; Marks JD; Huang Q; Rudnick SI; Xiong C; Hittelman WN; Wen X; Marks JW; Cheung LH; Boland K; Li C; Adams GP; Rosenblum MG
    Mol Cancer Ther; 2012 Jan; 11(1):143-53. PubMed ID: 22090420
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Improvement of a recombinant anti-monkey anti-CD3 diphtheria toxin based immunotoxin by yeast display affinity maturation of the scFv.
    Wang Z; Kim GB; Woo JH; Liu YY; Mathias A; Stavrou S; Neville DM
    Bioconjug Chem; 2007; 18(3):947-55. PubMed ID: 17352456
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The role of valency in the selection of anti-carbohydrate single-chain Fvs from phage display libraries.
    MacKenzie R; To R
    J Immunol Methods; 1998 Nov; 220(1-2):39-49. PubMed ID: 9839924
    [TBL] [Abstract][Full Text] [Related]  

  • 26. In vitro antibody evolution targeting germline hot spots to increase activity of an anti-CD22 immunotoxin.
    Ho M; Kreitman RJ; Onda M; Pastan I
    J Biol Chem; 2005 Jan; 280(1):607-17. PubMed ID: 15491997
    [TBL] [Abstract][Full Text] [Related]  

  • 27. HA22 (R490A) is a recombinant immunotoxin with increased antitumor activity without an increase in animal toxicity.
    Bang S; Nagata S; Onda M; Kreitman RJ; Pastan I
    Clin Cancer Res; 2005 Feb; 11(4):1545-50. PubMed ID: 15746059
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Two-step in vitro antibody affinity maturation enables estradiol-17beta assays with more than 10-fold higher sensitivity.
    Kobayashi N; Oyama H; Kato Y; Goto J; Söderlind E; Borrebaeck CA
    Anal Chem; 2010 Feb; 82(3):1027-38. PubMed ID: 20047279
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Antitumor activity of immunotoxins with T-cell receptor-like specificity against human melanoma xenografts.
    Klechevsky E; Gallegos M; Denkberg G; Palucka K; Banchereau J; Cohen C; Reiter Y
    Cancer Res; 2008 Aug; 68(15):6360-7. PubMed ID: 18676861
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Antigen binding and cytotoxic properties of a recombinant immunotoxin incorporating the lytic peptide, melittin.
    Dunn RD; Weston KM; Longhurst TJ; Lilley GG; Rivett DE; Hudson PJ; Raison RL
    Immunotechnology; 1996 Sep; 2(3):229-40. PubMed ID: 9373315
    [TBL] [Abstract][Full Text] [Related]  

  • 31. A novel EGFR-specific recombinant ricin-panitumumab (scFv) immunotoxin against breast and colorectal cancer cell lines; in silico and in vitro analyses.
    Naemi AA; Salmanian AH; Noormohammadi Z; Amani J
    Eur J Pharmacol; 2023 Sep; 955():175894. PubMed ID: 37429519
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Antitumor activity of SS(dsFv)PE38 and SS1(dsFv)PE38, recombinant antimesothelin immunotoxins against human gynecologic cancers grown in organotypic culture in vitro.
    Hassan R; Lerner MR; Benbrook D; Lightfoot SA; Brackett DJ; Wang QC; Pastan I
    Clin Cancer Res; 2002 Nov; 8(11):3520-6. PubMed ID: 12429643
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Construction and characterization of novel, recombinant immunotoxins targeting the Her2/neu oncogene product: in vitro and in vivo studies.
    Cao Y; Marks JD; Marks JW; Cheung LH; Kim S; Rosenblum MG
    Cancer Res; 2009 Dec; 69(23):8987-95. PubMed ID: 19934334
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Disulfide bond bridged divalent antibody-toxin, (Fab-PE38fl)2, with the toxin PE38 fused to the light chain.
    Won J; Choe M
    J Microbiol Biotechnol; 2008 Aug; 18(8):1475-81. PubMed ID: 18756111
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Improvement of anti-Burkholderia mouse monoclonal antibody from various phage-displayed single-chain antibody libraries.
    Kim HS; Lo SC; Wear DJ; Stojadinovic A; Weina PJ; Izadjoo MJ
    J Immunol Methods; 2011 Sep; 372(1-2):146-61. PubMed ID: 21787781
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Granzyme B-based cytolytic fusion protein targeting EpCAM specifically kills triple negative breast cancer cells in vitro and inhibits tumor growth in a subcutaneous mouse tumor model.
    Amoury M; Kolberg K; Pham AT; Hristodorov D; Mladenov R; Di Fiore S; Helfrich W; Kiessling F; Fischer R; Pardo A; Thepen T; Hussain AF; Nachreiner T; Barth S
    Cancer Lett; 2016 Mar; 372(2):201-9. PubMed ID: 26806809
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries.
    Cembrola B; Ruzza V; Troise F; Esposito ML; Sasso E; Cafaro V; Passariello M; Visconte F; Raia M; Del Vecchio L; D'Alise AM; Cortese R; Scarselli E; Zambrano N; De Lorenzo C; Nicosia A
    Biomed Res Int; 2019; 2019():6051870. PubMed ID: 31976323
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Anti-estradiol-17beta single-chain Fv fragments: Generation, characterization, gene randomization, and optimized phage display.
    Kobayashi N; Kato Y; Oyama H; Taga S; Niwa T; Sun P; Ohtoyo M; Goto J
    Steroids; 2008 Dec; 73(14):1485-99. PubMed ID: 18824188
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Development of a recombinant hCG-specific single chain immunotoxin cytotoxic to hCG expressing cancer cells.
    Nand KN; Gupta JC; Panda AK; Jain SK
    Protein Expr Purif; 2015 Feb; 106():10-7. PubMed ID: 25448825
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein.
    Pavoni E; Flego M; Dupuis ML; Barca S; Petronzelli F; Anastasi AM; D'Alessio V; Pelliccia A; Vaccaro P; Monteriù G; Ascione A; De Santis R; Felici F; Cianfriglia M; Minenkova O
    BMC Cancer; 2006 Feb; 6():41. PubMed ID: 16504122
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.