656 related articles for article (PubMed ID: 20826664)
1. Reduced survival of motor neuron (SMN) protein in motor neuronal progenitors functions cell autonomously to cause spinal muscular atrophy in model mice expressing the human centromeric (SMN2) gene.
Park GH; Maeno-Hikichi Y; Awano T; Landmesser LT; Monani UR
J Neurosci; 2010 Sep; 30(36):12005-19. PubMed ID: 20826664
[TBL] [Abstract][Full Text] [Related]
2. Survival motor neuron protein in motor neurons determines synaptic integrity in spinal muscular atrophy.
Martinez TL; Kong L; Wang X; Osborne MA; Crowder ME; Van Meerbeke JP; Xu X; Davis C; Wooley J; Goldhamer DJ; Lutz CM; Rich MM; Sumner CJ
J Neurosci; 2012 Jun; 32(25):8703-15. PubMed ID: 22723710
[TBL] [Abstract][Full Text] [Related]
3. Limited phenotypic effects of selectively augmenting the SMN protein in the neurons of a mouse model of severe spinal muscular atrophy.
Lee AJ; Awano T; Park GH; Monani UR
PLoS One; 2012; 7(9):e46353. PubMed ID: 23029491
[TBL] [Abstract][Full Text] [Related]
4. Motor transmission defects with sex differences in a new mouse model of mild spinal muscular atrophy.
Deguise MO; De Repentigny Y; Tierney A; Beauvais A; Michaud J; Chehade L; Thabet M; Paul B; Reilly A; Gagnon S; Renaud JM; Kothary R
EBioMedicine; 2020 May; 55():102750. PubMed ID: 32339936
[TBL] [Abstract][Full Text] [Related]
5. Reduced SMN protein impairs maturation of the neuromuscular junctions in mouse models of spinal muscular atrophy.
Kariya S; Park GH; Maeno-Hikichi Y; Leykekhman O; Lutz C; Arkovitz MS; Landmesser LT; Monani UR
Hum Mol Genet; 2008 Aug; 17(16):2552-69. PubMed ID: 18492800
[TBL] [Abstract][Full Text] [Related]
6. The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy.
Monani UR; Sendtner M; Coovert DD; Parsons DW; Andreassi C; Le TT; Jablonka S; Schrank B; Rossoll W; Prior TW; Morris GE; Burghes AH
Hum Mol Genet; 2000 Feb; 9(3):333-9. PubMed ID: 10655541
[TBL] [Abstract][Full Text] [Related]
7. Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model.
Hua Y; Sahashi K; Rigo F; Hung G; Horev G; Bennett CF; Krainer AR
Nature; 2011 Oct; 478(7367):123-6. PubMed ID: 21979052
[TBL] [Abstract][Full Text] [Related]
8. A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.
Bowerman M; Murray LM; Beauvais A; Pinheiro B; Kothary R
Neuromuscul Disord; 2012 Mar; 22(3):263-76. PubMed ID: 22071333
[TBL] [Abstract][Full Text] [Related]
9. Motor neuronal repletion of the NMJ organizer, Agrin, modulates the severity of the spinal muscular atrophy disease phenotype in model mice.
Kim JK; Caine C; Awano T; Herbst R; Monani UR
Hum Mol Genet; 2017 Jul; 26(13):2377-2385. PubMed ID: 28379354
[TBL] [Abstract][Full Text] [Related]
10. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration.
Arnold WD; Duque S; Iyer CC; Zaworski P; McGovern VL; Taylor SJ; von Herrmann KM; Kobayashi DT; Chen KS; Kolb SJ; Paushkin SV; Burghes AH
PLoS One; 2016; 11(12):e0167077. PubMed ID: 27907033
[TBL] [Abstract][Full Text] [Related]
11. Pre-symptomatic development of lower motor neuron connectivity in a mouse model of severe spinal muscular atrophy.
Murray LM; Lee S; Bäumer D; Parson SH; Talbot K; Gillingwater TH
Hum Mol Genet; 2010 Feb; 19(3):420-33. PubMed ID: 19884170
[TBL] [Abstract][Full Text] [Related]
12. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
Kannan A; Jiang X; He L; Ahmad S; Gangwani L
Brain; 2020 Jan; 143(1):69-93. PubMed ID: 31828288
[TBL] [Abstract][Full Text] [Related]
13. Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn
Reedich EJ; Kalski M; Armijo N; Cox GA; DiDonato CJ
Exp Neurol; 2021 Mar; 337():113587. PubMed ID: 33382987
[TBL] [Abstract][Full Text] [Related]
14. Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice.
de la Fuente S; Sansa A; Periyakaruppiah A; Garcera A; Soler RM
Mol Neurobiol; 2019 Jun; 56(6):4414-4427. PubMed ID: 30327977
[TBL] [Abstract][Full Text] [Related]
15. Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.
Murray LM; Comley LH; Thomson D; Parkinson N; Talbot K; Gillingwater TH
Hum Mol Genet; 2008 Apr; 17(7):949-62. PubMed ID: 18065780
[TBL] [Abstract][Full Text] [Related]
16. Restoration of SMN to Emx-1 expressing cortical neurons is not sufficient to provide benefit to a severe mouse model of Spinal Muscular Atrophy.
Taylor AS; Glascock JJ; Rose FF; Lutz C; Lorson CL
Transgenic Res; 2013 Oct; 22(5):1029-36. PubMed ID: 23512182
[TBL] [Abstract][Full Text] [Related]
17. Hypothermia improves disease manifestations in SMA mice via SMN augmentation.
Tsai LK; Chen CL; Tsai YC; Ting CH; Chien YH; Lee NC; Hwu WL
Hum Mol Genet; 2016 Feb; 25(4):631-41. PubMed ID: 26647309
[TBL] [Abstract][Full Text] [Related]
18. Proteomic assessment of a cell model of spinal muscular atrophy.
Wu CY; Whye D; Glazewski L; Choe L; Kerr D; Lee KH; Mason RW; Wang W
BMC Neurosci; 2011 Mar; 12():25. PubMed ID: 21385431
[TBL] [Abstract][Full Text] [Related]
19. Muscle-specific SMN reduction reveals motor neuron-independent disease in spinal muscular atrophy models.
Kim JK; Jha NN; Feng Z; Faleiro MR; Chiriboga CA; Wei-Lapierre L; Dirksen RT; Ko CP; Monani UR
J Clin Invest; 2020 Mar; 130(3):1271-1287. PubMed ID: 32039917
[TBL] [Abstract][Full Text] [Related]
20. Loganin possesses neuroprotective properties, restores SMN protein and activates protein synthesis positive regulator Akt/mTOR in experimental models of spinal muscular atrophy.
Tseng YT; Chen CS; Jong YJ; Chang FR; Lo YC
Pharmacol Res; 2016 Sep; 111():58-75. PubMed ID: 27241020
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]