BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 20827386)

  • 1. Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.
    Gangwal K; Close D; Enriquez CA; Hill CP; Lessnick SL
    Genes Cancer; 2010 Feb; 1(2):177-187. PubMed ID: 20827386
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Microsatellites as EWS/FLI response elements in Ewing's sarcoma.
    Gangwal K; Sankar S; Hollenhorst PC; Kinsey M; Haroldsen SC; Shah AA; Boucher KM; Watkins WS; Jorde LB; Graves BJ; Lessnick SL
    Proc Natl Acad Sci U S A; 2008 Jul; 105(29):10149-54. PubMed ID: 18626011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance.
    Luo W; Gangwal K; Sankar S; Boucher KM; Thomas D; Lessnick SL
    Oncogene; 2009 Nov; 28(46):4126-32. PubMed ID: 19718047
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microsatellites are EWS/FLI response elements: genomic "junk" is EWS/FLI's treasure.
    Gangwal K; Lessnick SL
    Cell Cycle; 2008 Oct; 7(20):3127-32. PubMed ID: 18927503
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth.
    Johnson KM; Mahler NR; Saund RS; Theisen ER; Taslim C; Callender NW; Crow JC; Miller KR; Lessnick SL
    Proc Natl Acad Sci U S A; 2017 Sep; 114(37):9870-9875. PubMed ID: 28847958
    [TBL] [Abstract][Full Text] [Related]  

  • 6. EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma.
    Kinsey M; Smith R; Iyer AK; McCabe ER; Lessnick SL
    Cancer Res; 2009 Dec; 69(23):9047-55. PubMed ID: 19920188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma.
    Johnson KM; Taslim C; Saund RS; Lessnick SL
    PLoS One; 2017; 12(11):e0186275. PubMed ID: 29091716
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.
    Kinsey M; Smith R; Lessnick SL
    Mol Cancer Res; 2006 Nov; 4(11):851-9. PubMed ID: 17114343
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group.
    Monument MJ; Johnson KM; McIlvaine E; Abegglen L; Watkins WS; Jorde LB; Womer RB; Beeler N; Monovich L; Lawlor ER; Bridge JA; Schiffman JD; Krailo MD; Randall RL; Lessnick SL
    PLoS One; 2014; 9(8):e104378. PubMed ID: 25093581
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of EWS-ETS fusions in NIH3T3 cells reveals significant differences to Ewing's sarcoma.
    Braunreiter CL; Hancock JD; Coffin CM; Boucher KM; Lessnick SL
    Cell Cycle; 2006 Dec; 5(23):2753-9. PubMed ID: 17172842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma.
    Owen LA; Kowalewski AA; Lessnick SL
    PLoS One; 2008 Apr; 3(4):e1965. PubMed ID: 18414662
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microsatellites with macro-influence in ewing sarcoma.
    Monument MJ; Johnson KM; Grossmann AH; Schiffman JD; Randall RL; Lessnick SL
    Genes (Basel); 2012 Jul; 3(3):444-60. PubMed ID: 24704979
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG.
    Sorensen PH; Lessnick SL; Lopez-Terrada D; Liu XF; Triche TJ; Denny CT
    Nat Genet; 1994 Feb; 6(2):146-51. PubMed ID: 8162068
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SRE elements are binding sites for the fusion protein EWS-FLI-1.
    Magnaghi-Jaulin L; Masutani H; Robin P; Lipinski M; Harel-Bellan A
    Nucleic Acids Res; 1996 Mar; 24(6):1052-8. PubMed ID: 8604338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma.
    Smith R; Owen LA; Trem DJ; Wong JS; Whangbo JS; Golub TR; Lessnick SL
    Cancer Cell; 2006 May; 9(5):405-16. PubMed ID: 16697960
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins.
    Kim S; Denny CT; Wisdom R
    Mol Cell Biol; 2006 Apr; 26(7):2467-78. PubMed ID: 16537893
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities.
    Mao X; Miesfeldt S; Yang H; Leiden JM; Thompson CB
    J Biol Chem; 1994 Jul; 269(27):18216-22. PubMed ID: 7517940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature.
    Hancock JD; Lessnick SL
    Cell Cycle; 2008 Jan; 7(2):250-6. PubMed ID: 18256529
    [TBL] [Abstract][Full Text] [Related]  

  • 19. EWS/ETS fusions activate telomerase in Ewing's tumors.
    Takahashi A; Higashino F; Aoyagi M; Yoshida K; Itoh M; Kyo S; Ohno T; Taira T; Ariga H; Nakajima K; Hatta M; Kobayashi M; Sano H; Kohgo T; Shindoh M
    Cancer Res; 2003 Dec; 63(23):8338-44. PubMed ID: 14678994
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A link between basic fibroblast growth factor (bFGF) and EWS/FLI-1 in Ewing's sarcoma cells.
    Girnita L; Girnita A; Wang M; Meis-Kindblom JM; Kindblom LG; Larsson O
    Oncogene; 2000 Aug; 19(37):4298-301. PubMed ID: 10980604
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.