291 related articles for article (PubMed ID: 20829372)
1. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
Jeannet R; Mastio J; Macias-Garcia A; Oravecz A; Ashworth T; Geimer Le Lay AS; Jost B; Le Gras S; Ghysdael J; Gridley T; Honjo T; Radtke F; Aster JC; Chan S; Kastner P
Blood; 2010 Dec; 116(25):5443-54. PubMed ID: 20829372
[TBL] [Abstract][Full Text] [Related]
2. Deletion-based mechanisms of Notch1 activation in T-ALL: key roles for RAG recombinase and a conserved internal translational start site in Notch1.
Ashworth TD; Pear WS; Chiang MY; Blacklow SC; Mastio J; Xu L; Kelliher M; Kastner P; Chan S; Aster JC
Blood; 2010 Dec; 116(25):5455-64. PubMed ID: 20852131
[TBL] [Abstract][Full Text] [Related]
3. Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
Witkowski MT; Cimmino L; Hu Y; Trimarchi T; Tagoh H; McKenzie MD; Best SA; Tuohey L; Willson TA; Nutt SL; Busslinger M; Aifantis I; Smyth GK; Dickins RA
Leukemia; 2015 Jun; 29(6):1301-11. PubMed ID: 25655195
[TBL] [Abstract][Full Text] [Related]
4. Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells.
Masiero M; Minuzzo S; Pusceddu I; Moserle L; Persano L; Agnusdei V; Tosello V; Basso G; Amadori A; Indraccolo S
Leukemia; 2011 Apr; 25(4):588-98. PubMed ID: 21263446
[TBL] [Abstract][Full Text] [Related]
5. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.
Gómez-del Arco P; Kashiwagi M; Jackson AF; Naito T; Zhang J; Liu F; Kee B; Vooijs M; Radtke F; Redondo JM; Georgopoulos K
Immunity; 2010 Nov; 33(5):685-98. PubMed ID: 21093322
[TBL] [Abstract][Full Text] [Related]
6. The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.
Choi SH; Severson E; Pear WS; Liu XS; Aster JC; Blacklow SC
PLoS One; 2017; 12(10):e0185762. PubMed ID: 29023469
[TBL] [Abstract][Full Text] [Related]
7. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.
Durinck K; Wallaert A; Van de Walle I; Van Loocke W; Volders PJ; Vanhauwaert S; Geerdens E; Benoit Y; Van Roy N; Poppe B; Soulier J; Cools J; Mestdagh P; Vandesompele J; Rondou P; Van Vlierberghe P; Taghon T; Speleman F
Haematologica; 2014 Dec; 99(12):1808-16. PubMed ID: 25344525
[TBL] [Abstract][Full Text] [Related]
8. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL.
Sontani Y; Chapman G; Papathanasiou P; Dunwoodie S; Goodnow CC; Hoyne GF
Leuk Res; 2011 Nov; 35(11):1512-9. PubMed ID: 21840596
[TBL] [Abstract][Full Text] [Related]
9. DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice.
Minuzzo S; Agnusdei V; Pusceddu I; Pinazza M; Moserle L; Masiero M; Rossi E; Crescenzi M; Hoey T; Ponzoni M; Amadori A; Indraccolo S
Carcinogenesis; 2015 Jan; 36(1):115-21. PubMed ID: 25355291
[TBL] [Abstract][Full Text] [Related]
10. Epigenetic regulation of the Ink4a-Arf (Cdkn2a) tumor suppressor locus in the initiation and progression of Notch1-driven T cell acute lymphoblastic leukemia.
Volanakis EJ; Boothby MR; Sherr CJ
Exp Hematol; 2013 Apr; 41(4):377-86. PubMed ID: 23178376
[TBL] [Abstract][Full Text] [Related]
11. High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia.
Chiang MY; Wang Q; Gormley AC; Stein SJ; Xu L; Shestova O; Aster JC; Pear WS
Blood; 2016 Nov; 128(18):2229-2240. PubMed ID: 27670423
[TBL] [Abstract][Full Text] [Related]
12. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.
Medyouf H; Gao X; Armstrong F; Gusscott S; Liu Q; Gedman AL; Matherly LH; Schultz KR; Pflumio F; You MJ; Weng AP
Blood; 2010 Feb; 115(6):1175-84. PubMed ID: 20008304
[TBL] [Abstract][Full Text] [Related]
13. Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
Aste-Amézaga M; Zhang N; Lineberger JE; Arnold BA; Toner TJ; Gu M; Huang L; Vitelli S; Vo KT; Haytko P; Zhao JZ; Baleydier F; L'Heureux S; Wang H; Gordon WR; Thoryk E; Andrawes MB; Tiyanont K; Stegmaier K; Roti G; Ross KN; Franlin LL; Wang H; Wang F; Chastain M; Bett AJ; Audoly LP; Aster JC; Blacklow SC; Huber HE
PLoS One; 2010 Feb; 5(2):e9094. PubMed ID: 20161710
[TBL] [Abstract][Full Text] [Related]
14. An activating intragenic deletion in NOTCH1 in human T-ALL.
Haydu JE; De Keersmaecker K; Duff MK; Paietta E; Racevskis J; Wiernik PH; Rowe JM; Ferrando A
Blood; 2012 May; 119(22):5211-4. PubMed ID: 22510873
[TBL] [Abstract][Full Text] [Related]
15. Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.
Lee SH; Jeong EG; Yoo NJ; Lee SH
APMIS; 2007 Dec; 115(12):1357-63. PubMed ID: 18184405
[TBL] [Abstract][Full Text] [Related]
16. The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.
Geimer Le Lay AS; Oravecz A; Mastio J; Jung C; Marchal P; Ebel C; Dembélé D; Jost B; Le Gras S; Thibault C; Borggrefe T; Kastner P; Chan S
Sci Signal; 2014 Mar; 7(317):ra28. PubMed ID: 24643801
[TBL] [Abstract][Full Text] [Related]
17. Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
Tatarek J; Cullion K; Ashworth T; Gerstein R; Aster JC; Kelliher MA
Blood; 2011 Aug; 118(6):1579-90. PubMed ID: 21670468
[TBL] [Abstract][Full Text] [Related]
18. Notch and Ikaros: not only converging players in T cell leukemia.
Bellavia D; Mecarozzi M; Campese AF; Grazioli P; Gulino A; Screpanti I
Cell Cycle; 2007 Nov; 6(22):2730-4. PubMed ID: 18032925
[TBL] [Abstract][Full Text] [Related]
19. Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.
Kong G; Du J; Liu Y; Meline B; Chang YI; Ranheim EA; Wang J; Zhang J
J Biol Chem; 2013 Jun; 288(25):18219-27. PubMed ID: 23673656
[TBL] [Abstract][Full Text] [Related]
20. MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
Pajcini KV; Xu L; Shao L; Petrovic J; Palasiewicz K; Ohtani Y; Bailis W; Lee C; Wertheim GB; Mani R; Muthusamy N; Li Y; Meijerink JPP; Blacklow SC; Faryabi RB; Cherry S; Pear WS
Sci Signal; 2017 Nov; 10(505):. PubMed ID: 29138297
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
