BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 20833634)

  • 1. Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.
    Malina J; Kasparkova J; Farrell NP; Brabec V
    Nucleic Acids Res; 2011 Jan; 39(2):720-8. PubMed ID: 20833634
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Spontaneous translocation of antitumor oxaliplatin, its enantiomeric analogue, and Cisplatin from one strand to another in double-helical DNA.
    Malina J; Natile G; Brabec V
    Chemistry; 2013 Sep; 19(36):11984-91. PubMed ID: 23873652
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: thermodynamic analysis and chemical probing.
    Malina J; Farrell NP; Brabec V
    Chem Asian J; 2011 Jun; 6(6):1566-74. PubMed ID: 21557487
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A; Berners-Price SJ; Davies MS; Thomas DS; Humphreys AS; Farrell N
    J Am Chem Soc; 2004 Feb; 126(7):2166-80. PubMed ID: 14971952
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antitumor bifunctional dinuclear Pt(II) complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
    Muchova T; Quintal SM; Farrell NP; Brabec V; Kasparkova J
    J Biol Inorg Chem; 2012 Feb; 17(2):239-45. PubMed ID: 21938443
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cooperative effects in long-range 1,4 DNA-DNA interstrand cross-links formed by polynuclear platinum complexes: an unexpected syn orientation of adenine bases outside the binding sites.
    Qu Y; Scarsdale NJ; Tran MC; Farrell NP
    J Biol Inorg Chem; 2003 Jan; 8(1-2):19-28. PubMed ID: 12459895
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent.
    Brabec V; Kaspárková J; Vrána O; Nováková O; Cox JW; Qu Y; Farrell N
    Biochemistry; 1999 May; 38(21):6781-90. PubMed ID: 10346899
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Translesion DNA synthesis across double-base lesions derived from cross-links of an antitumor trinuclear platinum compound: primer extension, conformational and thermodynamic studies.
    Novakova O; Farrell NP; Brabec V
    Metallomics; 2018 Jan; 10(1):132-144. PubMed ID: 29242879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural consequences of a 3'-->3' DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex.
    Qu Y; Tran MC; Farrell NP
    J Biol Inorg Chem; 2009 Aug; 14(6):969-77. PubMed ID: 19415349
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464.
    Zehnulova J; Kasparkova J; Farrell N; Brabec V
    J Biol Chem; 2001 Jun; 276(25):22191-9. PubMed ID: 11303029
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt(II) complexes.
    Florian J; Kasparkova J; Farrell NP; Brabec V
    J Biol Inorg Chem; 2012 Feb; 17(2):187-96. PubMed ID: 21894503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair.
    Kasparkova J; Zehnulova J; Farrell N; Brabec V
    J Biol Chem; 2002 Dec; 277(50):48076-86. PubMed ID: 12226099
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes.
    Qu Y; Scarsdale NJ; Tran MC; Farrell N
    J Inorg Biochem; 2004 Oct; 98(10):1585-90. PubMed ID: 15458820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.
    Ruhayel RA; Moniodis JJ; Yang X; Kasparkova J; Brabec V; Berners-Price SJ; Farrell NP
    Chemistry; 2009 Sep; 15(37):9365-74. PubMed ID: 19691069
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.
    Mlcouskova J; Malina J; Novohradsky V; Kasparkova J; Komeda S; Brabec V
    Biochim Biophys Acta; 2012 Oct; 1820(10):1502-11. PubMed ID: 22683702
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding.
    Kasparkova J; Vrana O; Farrell N; Brabec V
    J Inorg Biochem; 2004 Oct; 98(10):1560-9. PubMed ID: 15458817
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular pharmacology of polynuclear platinum anti-cancer agents.
    Roberts JD; Peroutka J; Farrell N
    J Inorg Biochem; 1999 Oct; 77(1-2):51-7. PubMed ID: 10626354
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
    Berners-Price SJ; Davies MS; Cox JW; Thomas DS; Farrell N
    Chemistry; 2003 Feb; 9(3):713-25. PubMed ID: 12569464
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex.
    Hofr C; Farrell N; Brabec V
    Nucleic Acids Res; 2001 May; 29(10):2034-40. PubMed ID: 11353072
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA binding by antitumor trans-[PtCl2(NH3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts.
    Kasparkova J; Novakova O; Farrell N; Brabec V
    Biochemistry; 2003 Jan; 42(3):792-800. PubMed ID: 12534292
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.