These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. A randomized, double-blind, placebo-controlled, delayed start study to assess rasagiline as a disease modifying therapy in Parkinson's disease (the ADAGIO study): rationale, design, and baseline characteristics. Olanow CW; Hauser RA; Jankovic J; Langston W; Lang A; Poewe W; Tolosa E; Stocchi F; Melamed E; Eyal E; Rascol O Mov Disord; 2008 Nov; 23(15):2194-201. PubMed ID: 18932271 [TBL] [Abstract][Full Text] [Related]
4. Why have we failed to achieve neuroprotection in Parkinson's disease? Olanow CW; Kieburtz K; Schapira AH Ann Neurol; 2008 Dec; 64 Suppl 2():S101-10. PubMed ID: 19127580 [TBL] [Abstract][Full Text] [Related]
5. Clinical measures of progression in Parkinson's disease. Poewe W Mov Disord; 2009; 24 Suppl 2():S671-6. PubMed ID: 19877235 [TBL] [Abstract][Full Text] [Related]
6. Subthalamic GAD gene transfer in Parkinson disease patients who are candidates for deep brain stimulation. During MJ; Kaplitt MG; Stern MB; Eidelberg D Hum Gene Ther; 2001 Aug; 12(12):1589-91. PubMed ID: 11529246 [TBL] [Abstract][Full Text] [Related]
7. Obstacles to the development of a neuroprotective therapy for Parkinson's disease. Stocchi F; Olanow CW Mov Disord; 2013 Jan; 28(1):3-7. PubMed ID: 23390094 [TBL] [Abstract][Full Text] [Related]
8. "Disease-modification" trials in Parkinson disease: target populations, endpoints and study design. Rascol O Neurology; 2009 Feb; 72(7 Suppl):S51-8. PubMed ID: 19221315 [TBL] [Abstract][Full Text] [Related]
9. Clinical neuroprotection in Parkinson's disease - still waiting for the breakthrough. Löhle M; Reichmann H J Neurol Sci; 2010 Feb; 289(1-2):104-14. PubMed ID: 19772974 [TBL] [Abstract][Full Text] [Related]
10. Are delayed-start design trials to show neuroprotection in Parkinson's disease fundamentally flawed? Clarke CE Mov Disord; 2008 Apr; 23(6):784-9. PubMed ID: 18175348 [TBL] [Abstract][Full Text] [Related]
11. The significance of defining preclinical or prodromal Parkinson's disease. Olanow CW; Obeso JA Mov Disord; 2012 Apr; 27(5):666-9. PubMed ID: 22508285 [TBL] [Abstract][Full Text] [Related]
12. The clinical progression of Parkinson's disease. Poewe W; Mahlknecht P Parkinsonism Relat Disord; 2009 Dec; 15 Suppl 4():S28-32. PubMed ID: 20123553 [TBL] [Abstract][Full Text] [Related]
14. Clinical approaches to the development of a neuroprotective therapy for PD. Olanow CW; Kieburtz K; Katz R Exp Neurol; 2017 Dec; 298(Pt B):246-251. PubMed ID: 28622912 [TBL] [Abstract][Full Text] [Related]
15. Outcome measures for clinical trials in Parkinson's disease: achievements and shortcomings. Marras C; Lang AE Expert Rev Neurother; 2004 Nov; 4(6):985-93. PubMed ID: 15853525 [TBL] [Abstract][Full Text] [Related]
16. Early pharmacologic treatment in Parkinson's disease. Hauser RA Am J Manag Care; 2010 Mar; 16 Suppl Implications():S100-7. PubMed ID: 20297870 [TBL] [Abstract][Full Text] [Related]
17. Washout and delayed start designs for identifying disease modifying effects in slowly progressive diseases using disease progression analysis. Ploeger BA; Holford NH Pharm Stat; 2009; 8(3):225-38. PubMed ID: 19025967 [TBL] [Abstract][Full Text] [Related]
18. A "cure" for Parkinson's disease: can neuroprotection be proven with current trial designs? Clarke CE Mov Disord; 2004 May; 19(5):491-8. PubMed ID: 15133811 [TBL] [Abstract][Full Text] [Related]
19. Can we achieve neuroprotection with currently available anti-parkinsonian interventions? Olanow CW Neurology; 2009 Feb; 72(7 Suppl):S59-64. PubMed ID: 19221316 [TBL] [Abstract][Full Text] [Related]
20. What's in the pipeline for the treatment of Parkinson's disease? Sommer DB; Stacy MA Expert Rev Neurother; 2008 Dec; 8(12):1829-39. PubMed ID: 19086879 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]