These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
157 related articles for article (PubMed ID: 20841376)
1. Quantifying and predicting the promiscuity and isoform specificity of small-molecule cytochrome P450 inhibitors. Nath A; Zientek MA; Burke BJ; Jiang Y; Atkins WM Drug Metab Dispos; 2010 Dec; 38(12):2195-203. PubMed ID: 20841376 [TBL] [Abstract][Full Text] [Related]
2. Insights into molecular basis of cytochrome p450 inhibitory promiscuity of compounds. Cheng F; Yu Y; Zhou Y; Shen Z; Xiao W; Liu G; Li W; Lee PW; Tang Y J Chem Inf Model; 2011 Oct; 51(10):2482-95. PubMed ID: 21875141 [TBL] [Abstract][Full Text] [Related]
3. Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity. Khojasteh SC; Prabhu S; Kenny JR; Halladay JS; Lu AY Eur J Drug Metab Pharmacokinet; 2011 Mar; 36(1):1-16. PubMed ID: 21336516 [TBL] [Abstract][Full Text] [Related]
4. Cytochrome P450 networks in chemical space. Lee S; Kim D Arch Pharm Res; 2010 Sep; 33(9):1361-74. PubMed ID: 20945135 [TBL] [Abstract][Full Text] [Related]
5. Application of support vector machines to in silico prediction of cytochrome p450 enzyme substrates and inhibitors. Yap CW; Xue Y; Li ZR; Chen YZ Curr Top Med Chem; 2006; 6(15):1593-607. PubMed ID: 16918471 [TBL] [Abstract][Full Text] [Related]
6. A quantitative index of substrate promiscuity. Nath A; Atkins WM Biochemistry; 2008 Jan; 47(1):157-66. PubMed ID: 18081310 [TBL] [Abstract][Full Text] [Related]
7. Development and Validation of a Higher-Throughput Cytochrome P450 Inhibition Assay with the Novel Cofactor-Supplemented Permeabilized Cryopreserved Human Hepatocytes (MetMax Human Hepatocytes). Palacharla VRC; Chunduru P; Ajjala DR; Bhyrapuneni G; Nirogi R; Li AP Drug Metab Dispos; 2019 Oct; 47(10):1032-1039. PubMed ID: 31375472 [TBL] [Abstract][Full Text] [Related]
8. A high throughput screening assay to screen for CYP2E1 metabolism and inhibition using a fluorogenic vivid p450 substrate. Marks BD; Smith RW; Braun HA; Goossens TA; Christenson M; Ozers MS; Lebakken CS; Trubetskoy OV Assay Drug Dev Technol; 2002 Nov; 1(1 Pt 1):73-81. PubMed ID: 15090158 [TBL] [Abstract][Full Text] [Related]
9. On the recognition of mammalian microsomal cytochrome P450 substrates and their characteristics: towards the prediction of human p450 substrate specificity and metabolism. Lewis DF Biochem Pharmacol; 2000 Aug; 60(3):293-306. PubMed ID: 10856424 [TBL] [Abstract][Full Text] [Related]
10. High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. VI. Simultaneous evaluation of inhibition potential of drugs on human hepatic isozymes CYP2A6, 3A4, 2C9, 2D6 and 2E1. Bu HZ; Magis L; Knuth K; Teitelbaum P Rapid Commun Mass Spectrom; 2001; 15(10):741-8. PubMed ID: 11344532 [TBL] [Abstract][Full Text] [Related]
11. Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Fontana E; Dansette PM; Poli SM Curr Drug Metab; 2005 Oct; 6(5):413-54. PubMed ID: 16248836 [TBL] [Abstract][Full Text] [Related]
12. Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. Xu F; Falck JR; Ortiz de Montellano PR; Kroetz DL J Pharmacol Exp Ther; 2004 Mar; 308(3):887-95. PubMed ID: 14634044 [TBL] [Abstract][Full Text] [Related]
13. Fluorometric high-throughput screening for inhibitors of cytochrome P450. Miller VP; Stresser DM; Blanchard AP; Turner S; Crespi CL Ann N Y Acad Sci; 2000; 919():26-32. PubMed ID: 11083094 [TBL] [Abstract][Full Text] [Related]
14. WhichCyp: prediction of cytochromes P450 inhibition. Rostkowski M; Spjuth O; Rydberg P Bioinformatics; 2013 Aug; 29(16):2051-2. PubMed ID: 23740742 [TBL] [Abstract][Full Text] [Related]