BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 20842641)

  • 1. Design, synthesis, and biological evaluation of 1,5-diaryl-1,2,4-triazole derivatives as selective cyclooxygenase-2 inhibitors.
    Jiang B; Zeng Y; Li MJ; Xu JY; Zhang YN; Wang QJ; Sun NY; Lu T; Wu XM
    Arch Pharm (Weinheim); 2010 Sep; 343(9):500-8. PubMed ID: 20842641
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and anti-inflammatory evaluation of a series of novel amino acid-binding 1,5-diarylpyrazole derivatives.
    Li MH; Yin LL; Cai MJ; Zhang WY; Huang Y; Wang X; Zhu XZ; Shen JK
    Acta Pharmacol Sin; 2005 Jul; 26(7):865-72. PubMed ID: 15960895
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2.
    El-Sayed MA; Abdel-Aziz NI; Abdel-Aziz AA; El-Azab AS; ElTahir KE
    Bioorg Med Chem; 2012 May; 20(10):3306-16. PubMed ID: 22516672
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
    Abdel-Aziz AA; ElTahir KE; Asiri YA
    Eur J Med Chem; 2011 May; 46(5):1648-55. PubMed ID: 21388719
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and pharmacological evaluation of 4-[2-alkylthio-5(4)-(4-substitutedphenyl)imidazole-4(5)yl]benzenesulfonamides as selective COX-2 inhibitors.
    Salimi M; Ghahremani MH; Naderi N; Amini M; Salimi E; Amanlou M; Abdi K; Salehi R; Shafiee A
    Acta Pharmacol Sin; 2007 Aug; 28(8):1254-60. PubMed ID: 17640491
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study.
    El-Sayed MA; Abdel-Aziz NI; Abdel-Aziz AA; El-Azab AS; Asiri YA; Eltahir KE
    Bioorg Med Chem; 2011 Jun; 19(11):3416-24. PubMed ID: 21570309
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
    Riendeau D; Percival MD; Boyce S; Brideau C; Charleson S; Cromlish W; Ethier D; Evans J; Falgueyret JP; Ford-Hutchinson AW; Gordon R; Greig G; Gresser M; Guay J; Kargman S; Léger S; Mancini JA; O'Neill G; Ouellet M; Rodger IW; Thérien M; Wang Z; Webb JK; Wong E; Chan CC
    Br J Pharmacol; 1997 May; 121(1):105-17. PubMed ID: 9146894
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel anti-inflammatory agents based on pyridazinone scaffold; design, synthesis and in vivo activity.
    Abouzid K; Bekhit SA
    Bioorg Med Chem; 2008 May; 16(10):5547-56. PubMed ID: 18430576
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Dec; 13(23):6425-34. PubMed ID: 16099663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of new water-soluble tetrazolide derivatives of celecoxib and rofecoxib as selective cyclooxygenase-2 (COX-2) inhibitors.
    Navidpour L; Amini M; Shafaroodi H; Abdi K; Ghahremani MH; Dehpour AR; Shafiee A
    Bioorg Med Chem Lett; 2006 Sep; 16(17):4483-7. PubMed ID: 16806914
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors.
    Praveen Rao PN; Amini M; Li H; Habeeb AG; Knaus EE
    J Med Chem; 2003 Nov; 46(23):4872-82. PubMed ID: 14584938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors.
    Navidpour L; Shafaroodi H; Abdi K; Amini M; Ghahremani MH; Dehpour AR; Shafiee A
    Bioorg Med Chem; 2006 Apr; 14(8):2507-17. PubMed ID: 16337127
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN; Chen QH; Knaus EE
    J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity.
    Gierse JK; Zhang Y; Hood WF; Walker MC; Trigg JS; Maziasz TJ; Koboldt CM; Muhammad JL; Zweifel BS; Masferrer JL; Isakson PC; Seibert K
    J Pharmacol Exp Ther; 2005 Mar; 312(3):1206-12. PubMed ID: 15494548
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a novel COX-2 inhibitor as an orally potent anti-pyretic and anti-inflammatory drug: design, synthesis, and structure-activity relationship.
    Hayashi S; Sumi Y; Ueno N; Murase A; Takada J
    Biochem Pharmacol; 2011 Oct; 82(7):755-68. PubMed ID: 21741371
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Aug; 13(15):4694-703. PubMed ID: 15914011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of 2-trifluoromethyl/sulfonamido-5,6-diaryl substituted imidazo[2,1-b]-1,3,4-thiadiazoles: a novel class of cyclooxygenase-2 inhibitors.
    Gadad AK; Palkar MB; Anand K; Noolvi MN; Boreddy TS; Wagwade J
    Bioorg Med Chem; 2008 Jan; 16(1):276-83. PubMed ID: 17937989
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors.
    Eren G; Unlü S; Nuñez MT; Labeaga L; Ledo F; Entrena A; Banoğlu E; Costantino G; Sahin MF
    Bioorg Med Chem; 2010 Sep; 18(17):6367-76. PubMed ID: 20692174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Apr; 13(7):2459-68. PubMed ID: 15755648
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
    Song Y; Connor DT; Sercel AD; Sorenson RJ; Doubleday R; Unangst PC; Roth BD; Beylin VG; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
    J Med Chem; 1999 Apr; 42(7):1161-9. PubMed ID: 10197960
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.