91 related articles for article (PubMed ID: 20845962)
1. Azole drugs trap cytochrome P450 EryK in alternative conformational states.
Montemiglio LC; Gianni S; Vallone B; Savino C
Biochemistry; 2010 Nov; 49(43):9199-206. PubMed ID: 20845962
[TBL] [Abstract][Full Text] [Related]
2. Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF.
Cupp-Vickery JR; Garcia C; Hofacre A; McGee-Estrada K
J Mol Biol; 2001 Aug; 311(1):101-10. PubMed ID: 11469860
[TBL] [Abstract][Full Text] [Related]
3. Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate.
Savino C; Montemiglio LC; Sciara G; Miele AE; Kendrew SG; Jemth P; Gianni S; Vallone B
J Biol Chem; 2009 Oct; 284(42):29170-9. PubMed ID: 19625248
[TBL] [Abstract][Full Text] [Related]
4. The role of erythromycin C-12 hydroxylase, EryK, as a substitute for PikC hydroxylase in pikromycin biosynthesis.
Lee SK; Basnet DB; Choi CY; Sohng JK; Ahn JS; Yoon YJ
Bioorg Chem; 2004 Dec; 32(6):549-59. PubMed ID: 15530995
[TBL] [Abstract][Full Text] [Related]
5. Structure of Ralstonia eutropha flavohemoglobin in complex with three antibiotic azole compounds.
El Hammi E; Warkentin E; Demmer U; Limam F; Marzouki NM; Ermler U; Baciou L
Biochemistry; 2011 Feb; 50(7):1255-64. PubMed ID: 21210640
[TBL] [Abstract][Full Text] [Related]
6. Functional analysis and crystallographic structure of clotrimazole bound OleP, a cytochrome P450 epoxidase from Streptomyces antibioticus involved in oleandomycin biosynthesis.
Montemiglio LC; Parisi G; Scaglione A; Sciara G; Savino C; Vallone B
Biochim Biophys Acta; 2016 Mar; 1860(3):465-75. PubMed ID: 26475642
[TBL] [Abstract][Full Text] [Related]
7. Mycobacterium tuberculosis CYP130: crystal structure, biophysical characterization, and interactions with antifungal azole drugs.
Ouellet H; Podust LM; de Montellano PR
J Biol Chem; 2008 Feb; 283(8):5069-80. PubMed ID: 18089574
[TBL] [Abstract][Full Text] [Related]
8. Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.
Basudhar D; Madrona Y; Kandel S; Lampe JN; Nishida CR; de Montellano PR
J Biol Chem; 2015 Apr; 290(16):10000-17. PubMed ID: 25670859
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.
Haines DC; Chen B; Tomchick DR; Bondlela M; Hegde A; Machius M; Peterson JA
Biochemistry; 2008 Mar; 47(12):3662-70. PubMed ID: 18298086
[TBL] [Abstract][Full Text] [Related]
10. Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1.
Chenge JT; Duyet LV; Swami S; McLean KJ; Kavanagh ME; Coyne AG; Rigby SE; Cheesman MR; Girvan HM; Levy CW; Rupp B; von Kries JP; Abell C; Leys D; Munro AW
J Biol Chem; 2017 Jan; 292(4):1310-1329. PubMed ID: 27932461
[TBL] [Abstract][Full Text] [Related]
11. Structural basis of human CYP51 inhibition by antifungal azoles.
Strushkevich N; Usanov SA; Park HW
J Mol Biol; 2010 Apr; 397(4):1067-78. PubMed ID: 20149798
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway.
Lim YR; Hong MK; Kim JK; Doan TT; Kim DH; Yun CH; Chun YJ; Kang LW; Kim D
Arch Biochem Biophys; 2012 Dec; 528(2):111-7. PubMed ID: 23000034
[TBL] [Abstract][Full Text] [Related]
13. Crystal structure and properties of CYP231A2 from the thermoacidophilic archaeon Picrophilus torridus.
Ho WW; Li H; Nishida CR; de Montellano PR; Poulos TL
Biochemistry; 2008 Feb; 47(7):2071-9. PubMed ID: 18197710
[TBL] [Abstract][Full Text] [Related]
14. How do azoles inhibit cytochrome P450 enzymes? A density functional study.
Balding PR; Porro CS; McLean KJ; Sutcliffe MJ; Maréchal JD; Munro AW; de Visser SP
J Phys Chem A; 2008 Dec; 112(50):12911-8. PubMed ID: 18563875
[TBL] [Abstract][Full Text] [Related]
15. Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of C-12 hydroxylase EryK from Saccharopolyspora erythraea.
Savino C; Sciara G; Miele AE; Kendrew SG; Vallone B
Protein Pept Lett; 2008; 15(10):1138-41. PubMed ID: 19075827
[TBL] [Abstract][Full Text] [Related]
16. Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450(cam) by an L244A mutation.
Verras A; Alian A; de Montellano PR
Protein Eng Des Sel; 2006 Nov; 19(11):491-6. PubMed ID: 16943206
[TBL] [Abstract][Full Text] [Related]
17. Crystal structure of CYP199A2, a para-substituted benzoic acid oxidizing cytochrome P450 from Rhodopseudomonas palustris.
Bell SG; Xu F; Forward I; Bartlam M; Rao Z; Wong LL
J Mol Biol; 2008 Nov; 383(3):561-74. PubMed ID: 18762195
[TBL] [Abstract][Full Text] [Related]
18. Redirecting P450 EryK specificity by rational site-directed mutagenesis.
Montemiglio LC; Macone A; Ardiccioni C; Avella G; Vallone B; Savino C
Biochemistry; 2013 May; 52(21):3678-87. PubMed ID: 23597312
[TBL] [Abstract][Full Text] [Related]
19. Structural basis for ligand promiscuity in cytochrome P450 3A4.
Ekroos M; Sjögren T
Proc Natl Acad Sci U S A; 2006 Sep; 103(37):13682-7. PubMed ID: 16954191
[TBL] [Abstract][Full Text] [Related]
20. Filling a hole in cytochrome P450 BM3 improves substrate binding and catalytic efficiency.
Huang WC; Westlake AC; Maréchal JD; Joyce MG; Moody PC; Roberts GC
J Mol Biol; 2007 Oct; 373(3):633-51. PubMed ID: 17868686
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
