These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 20852)

  • 21. Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state.
    Bystroff C; Oatley SJ; Kraut J
    Biochemistry; 1990 Apr; 29(13):3263-77. PubMed ID: 2185835
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Substrate and inhibitor complexes of dihydrofolate reductase from amethopterin-resistant L1210 cells.
    Neef VG; Huennekens FM
    Arch Biochem Biophys; 1975 Dec; 171(2):435-43. PubMed ID: 959
    [No Abstract]   [Full Text] [Related]  

  • 23. Critical role of phenylalanine 34 of human dihydrofolate reductase in substrate and inhibitor binding and in catalysis.
    Nakano T; Spencer HT; Appleman JR; Blakley RL
    Biochemistry; 1994 Aug; 33(33):9945-52. PubMed ID: 8061003
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Aliphatic (1)H, (13)C and (15)N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP(+) and folate.
    Loveridge EJ; Matthews SM; Williams C; Whittaker SB; Günther UL; Evans RM; Dawson WM; Crump MP; Allemann RK
    Biomol NMR Assign; 2013 Apr; 7(1):61-4. PubMed ID: 22415546
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Nuclear magnetic resonance study of interaction of ligands with streptococcus faecium dihydrofolate reductase labeled with [gamma-13C]tryptophan.
    London RE; Groff JP; Cocco L; Blakley RL
    Biochemistry; 1982 Aug; 21(18):4450-8. PubMed ID: 7126550
    [No Abstract]   [Full Text] [Related]  

  • 26. Role of the cellular oxidation-reduction state in methotrexate binding to dihydrofolate reductase and dissociation induced by reduced folates.
    Matherly LH; Anderson LA; Goldman ID
    Cancer Res; 1984 Jun; 44(6):2325-30. PubMed ID: 6609765
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Kinetics of substrate, coenzyme, and inhibitor binding to Escherichia coli dihydrofolate reductase.
    Cayley PJ; Dunn SM; King RW
    Biochemistry; 1981 Feb; 20(4):874-9. PubMed ID: 7011378
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Refolding of Escherichia coli dihydrofolate reductase: sequential formation of substrate binding sites.
    Frieden C
    Proc Natl Acad Sci U S A; 1990 Jun; 87(12):4413-6. PubMed ID: 2191290
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mutations of human dihydrofolate reductase causing decreased inhibition by methotrexate.
    Blakley RL; Appleman JR; Chunduru SK; Nakano T; Lewis WS; Harris SE
    Adv Exp Med Biol; 1993; 338():473-9. PubMed ID: 8304162
    [No Abstract]   [Full Text] [Related]  

  • 30. Equilibrium folding studies of tetrameric R67 dihydrofolate reductase.
    Zhuang P; Eisenstein E; Howell EE
    Biochemistry; 1994 Apr; 33(14):4237-44. PubMed ID: 8155640
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Identification of dihydrofolate reductase in rabbit brain.
    Spector R; Levy P; Abelson HT
    Biochem Pharmacol; 1977 Aug; 26(16):1507-11. PubMed ID: 901568
    [No Abstract]   [Full Text] [Related]  

  • 32. Dihydrofolate reductases of Escherichia coli and bacteriophage Tr. A spectrofluorometric study.
    Erickson JS; Mathews CK
    Biochemistry; 1973 Jan; 12(3):372-80. PubMed ID: 4405201
    [No Abstract]   [Full Text] [Related]  

  • 33. Effects on dihydrofolate reductase of methotrexate metabolites and intracellular folates formed following methotrexate exposure of human breast cancer cells.
    Drake JC; Allegra CJ; Baram J; Kaufman BT; Chabner BA
    Biochem Pharmacol; 1987 Jul; 36(14):2416-8. PubMed ID: 2440441
    [No Abstract]   [Full Text] [Related]  

  • 34. Effects of nitrous oxide and methotrexate administration on hepatic methionine synthetase and dihydrofolate reductase activities, hepatic folates, and formate oxidation in rats.
    Black KA; Tephly TR
    Mol Pharmacol; 1983 May; 23(3):724-30. PubMed ID: 6865915
    [No Abstract]   [Full Text] [Related]  

  • 35. Methotrexate, a high-affinity pseudosubstrate of dihydrofolate reductase.
    Williams JW; Morrison JF; Duggleby RG
    Biochemistry; 1979 Jun; 18(12):2567-73. PubMed ID: 36135
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Evidence for two reduced triphosphopyridine nucleotide binding sites on dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli.
    Williams MN; Greenfield NJ; Hoogsteen K
    J Biol Chem; 1973 Sep; 248(18):6380-6. PubMed ID: 4147160
    [No Abstract]   [Full Text] [Related]  

  • 37. Two different species of dihydrofolate reductase in mammalian cells differentially resistant to amethopterin and methasquin.
    Albrecht AM; Biedler JL; Hutchison DJ
    Cancer Res; 1972 Jul; 32(7):1539-46. PubMed ID: 4402276
    [No Abstract]   [Full Text] [Related]  

  • 38. Dihydrofolate reductase: the current story.
    Gready JE
    Nature; 1979 Dec; 282(5740):674-5. PubMed ID: 514346
    [No Abstract]   [Full Text] [Related]  

  • 39. Conformational flexibility and protein specificity.
    Roberts GC
    Ciba Found Symp; 1991; 158():169-82; discussion 182-6, 204-12. PubMed ID: 1935420
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Reversal of methotrexate binding to dihydrofolate reductase by dihydrofolate. Studies with pure enzyme and computer modeling using network thermodynamics.
    White JC
    J Biol Chem; 1979 Nov; 254(21):10889-95. PubMed ID: 387759
    [No Abstract]   [Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.