BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

329 related articles for article (PubMed ID: 20853887)

  • 1. Comprehensive structural and functional characterization of the human kinome by protein structure modeling and ligand virtual screening.
    Brylinski M; Skolnick J
    J Chem Inf Model; 2010 Oct; 50(10):1839-54. PubMed ID: 20853887
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FINDSITE(comb): a threading/structure-based, proteomic-scale virtual ligand screening approach.
    Zhou H; Skolnick J
    J Chem Inf Model; 2013 Jan; 53(1):230-40. PubMed ID: 23240691
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cross-reactivity virtual profiling of the human kinome by X-react(KIN): a chemical systems biology approach.
    Brylinski M; Skolnick J
    Mol Pharm; 2010 Dec; 7(6):2324-33. PubMed ID: 20958088
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nonlinear scoring functions for similarity-based ligand docking and binding affinity prediction.
    Brylinski M
    J Chem Inf Model; 2013 Nov; 53(11):3097-112. PubMed ID: 24171431
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel kinase inhibitors by reshuffling ligand functionalities across the human kinome.
    Vidović D; Muskal SM; Schürer SC
    J Chem Inf Model; 2012 Dec; 52(12):3107-15. PubMed ID: 23121521
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrating ligand-based and protein-centric virtual screening of kinase inhibitors using ensembles of multiple protein kinase genes and conformations.
    Dixit A; Verkhivker GM
    J Chem Inf Model; 2012 Oct; 52(10):2501-15. PubMed ID: 22992037
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FINDSITE
    Zhou H; Cao H; Skolnick J
    J Chem Inf Model; 2018 Nov; 58(11):2343-2354. PubMed ID: 30278128
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pocketome of human kinases: prioritizing the ATP binding sites of (yet) untapped protein kinases for drug discovery.
    Volkamer A; Eid S; Turk S; Jaeger S; Rippmann F; Fulle S
    J Chem Inf Model; 2015 Mar; 55(3):538-49. PubMed ID: 25557645
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A Proteometric Analysis of Human Kinome: Insight into Discriminant Conformation-dependent Residues.
    Bosc N; Wroblowski B; Aci-Sèche S; Meyer C; Bonnet P
    ACS Chem Biol; 2015 Dec; 10(12):2827-40. PubMed ID: 26411811
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein flexibility in ligand docking and virtual screening to protein kinases.
    Cavasotto CN; Abagyan RA
    J Mol Biol; 2004 Mar; 337(1):209-25. PubMed ID: 15001363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FRAGSITE: A Fragment-Based Approach for Virtual Ligand Screening.
    Zhou H; Cao H; Skolnick J
    J Chem Inf Model; 2021 Apr; 61(4):2074-2089. PubMed ID: 33724022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. KinMap: a web-based tool for interactive navigation through human kinome data.
    Eid S; Turk S; Volkamer A; Rippmann F; Fulle S
    BMC Bioinformatics; 2017 Jan; 18(1):16. PubMed ID: 28056780
    [TBL] [Abstract][Full Text] [Related]  

  • 13. kinDOCK: a tool for comparative docking of protein kinase ligands.
    Martin L; Catherinot V; Labesse G
    Nucleic Acids Res; 2006 Jul; 34(Web Server issue):W325-9. PubMed ID: 16845019
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure.
    Park H; Chi O; Kim J; Hong S
    J Chem Inf Model; 2011 Nov; 51(11):2986-93. PubMed ID: 22017333
    [TBL] [Abstract][Full Text] [Related]  

  • 15. INTEGRATING GENETIC AND STRUCTURAL DATA ON HUMAN PROTEIN KINOME IN NETWORK-BASED MODELING OF KINASE SENSITIVITIES AND RESISTANCE TO TARGETED AND PERSONALIZED ANTICANCER DRUGS.
    Verkhivker GM
    Pac Symp Biocomput; 2016; 21():45-56. PubMed ID: 26776172
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of chemically diverse Chk1 inhibitors by receptor-based virtual screening.
    Foloppe N; Fisher LM; Howes R; Potter A; Robertson AG; Surgenor AE
    Bioorg Med Chem; 2006 Jul; 14(14):4792-802. PubMed ID: 16574416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Large-scale proteomics analysis of the human kinome.
    Oppermann FS; Gnad F; Olsen JV; Hornberger R; Greff Z; Kéri G; Mann M; Daub H
    Mol Cell Proteomics; 2009 Jul; 8(7):1751-64. PubMed ID: 19369195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FINDSITE(X): a structure-based, small molecule virtual screening approach with application to all identified human GPCRs.
    Zhou H; Skolnick J
    Mol Pharm; 2012 Jun; 9(6):1775-84. PubMed ID: 22574683
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FRAGSITE2: A structure and fragment-based approach for virtual ligand screening.
    Zhou H; Skolnick J
    Protein Sci; 2024 Jan; 33(1):e4869. PubMed ID: 38100293
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of novel checkpoint kinase 1 inhibitors by virtual screening based on multiple crystal structures.
    Li Y; Kim DJ; Ma W; Lubet RA; Bode AM; Dong Z
    J Chem Inf Model; 2011 Nov; 51(11):2904-14. PubMed ID: 21955044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.