173 related articles for article (PubMed ID: 20854805)
1. Antagonistic effect of flavonoids on NSC-741909-mediated antitumor activity via scavenging of reactive oxygen species.
Guo W; Wei X; Wu S; Wang L; Peng H; Wang J; Fang B
Eur J Pharmacol; 2010 Dec; 649(1-3):51-8. PubMed ID: 20854805
[TBL] [Abstract][Full Text] [Related]
2. Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition.
Guo W; Wu S; Wang L; Wei X; Liu X; Wang J; Lu Z; Hollingshead M; Fang B
PLoS One; 2011; 6(12):e28487. PubMed ID: 22174819
[TBL] [Abstract][Full Text] [Related]
3. Inhibiting JNK dephosphorylation and induction of apoptosis by novel anticancer agent NSC-741909 in cancer cells.
Wei X; Guo W; Wu S; Wang L; Lu Y; Xu B; Liu J; Fang B
J Biol Chem; 2009 Jun; 284(25):16948-16955. PubMed ID: 19414586
[TBL] [Abstract][Full Text] [Related]
4. Oxidative stress in NSC-741909-induced apoptosis of cancer cells.
Wei X; Guo W; Wu S; Wang L; Huang P; Liu J; Fang B
J Transl Med; 2010 Apr; 8():37. PubMed ID: 20398386
[TBL] [Abstract][Full Text] [Related]
5. Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Vrana JA; Grant S
Blood; 2001 Apr; 97(7):2105-14. PubMed ID: 11264178
[TBL] [Abstract][Full Text] [Related]
6. Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer.
Kao SJ; Lee WJ; Chang JH; Chow JM; Chung CL; Hung WY; Chien MH
Environ Toxicol; 2017 Apr; 32(4):1426-1438. PubMed ID: 27539140
[TBL] [Abstract][Full Text] [Related]
7. Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity.
Chuang SM; Liou GY; Yang JL
Carcinogenesis; 2000 Aug; 21(8):1491-500. PubMed ID: 10910949
[TBL] [Abstract][Full Text] [Related]
8. Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.
Tyagi A; Agarwal R; Agarwal C
Oncogene; 2003 Mar; 22(9):1302-16. PubMed ID: 12618755
[TBL] [Abstract][Full Text] [Related]
9. The mitogen-activated protein kinase kinase (mek) inhibitor PD98059 elevates primary cultured rat hepatocyte glutathione levels independent of inhibiting mek.
Kim SK; Abdelmegeed MA; Novak RF
Drug Metab Dispos; 2006 Apr; 34(4):683-9. PubMed ID: 16443668
[TBL] [Abstract][Full Text] [Related]
10. Erlotinib induces the human non-small-cell lung cancer cells apoptosis via activating ROS-dependent JNK pathways.
Shan F; Shao Z; Jiang S; Cheng Z
Cancer Med; 2016 Nov; 5(11):3166-3175. PubMed ID: 27726288
[TBL] [Abstract][Full Text] [Related]
11. Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2.
Selimovic D; Hassan M; Haikel Y; Hengge UR
Cell Signal; 2008 Feb; 20(2):311-22. PubMed ID: 18068334
[TBL] [Abstract][Full Text] [Related]
12. Zn2+-induced ERK activation mediated by reactive oxygen species causes cell death in differentiated PC12 cells.
Seo SR; Chong SA; Lee SI; Sung JY; Ahn YS; Chung KC; Seo JT
J Neurochem; 2001 Aug; 78(3):600-10. PubMed ID: 11483663
[TBL] [Abstract][Full Text] [Related]
13. Activation of protein kinase C betaII/epsilon-c-Jun NH2-terminal kinase pathway and inhibition of mitogen-activated protein/extracellular signal-regulated kinase 1/2 phosphorylation in antitumor invasive activity induced by the polymethoxy flavonoid, nobiletin.
Miyata Y; Sato T; Yano M; Ito A
Mol Cancer Ther; 2004 Jul; 3(7):839-47. PubMed ID: 15252145
[TBL] [Abstract][Full Text] [Related]
14. Involvement of histone H3 phosphorylation through p38 MAPK pathway activation in casticin-induced cytocidal effects against the human promyelocytic cell line HL-60.
Kikuchi H; Yuan B; Yuhara E; Takagi N; Toyoda H
Int J Oncol; 2013 Dec; 43(6):2046-56. PubMed ID: 24064676
[TBL] [Abstract][Full Text] [Related]
15. Antioxidants inhibit JNK and p38 MAPK activation but not ERK 1/2 activation by angiotensin II in rat aortic smooth muscle cells.
Kyaw M; Yoshizumi M; Tsuchiya K; Kirima K; Tamaki T
Hypertens Res; 2001 May; 24(3):251-61. PubMed ID: 11409648
[TBL] [Abstract][Full Text] [Related]
16. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
Niu NK; Wang ZL; Pan ST; Ding HQ; Au GH; He ZX; Zhou ZW; Xiao G; Yang YX; Zhang X; Yang T; Chen XW; Qiu JX; Zhou SF
Drug Des Devel Ther; 2015; 9():1555-84. PubMed ID: 25792811
[TBL] [Abstract][Full Text] [Related]
17. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
Ou YC; Yang CR; Cheng CL; Raung SL; Hung YY; Chen CJ
Eur J Pharmacol; 2007 Jun; 563(1-3):49-60. PubMed ID: 17341418
[TBL] [Abstract][Full Text] [Related]
18. Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules or dominant negative mutants.
Brognard J; Dennis PA
Cell Death Differ; 2002 Sep; 9(9):893-904. PubMed ID: 12181740
[TBL] [Abstract][Full Text] [Related]
19. The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
Yu C; Rahmani M; Dent P; Grant S
Exp Cell Res; 2004 May; 295(2):555-66. PubMed ID: 15093752
[TBL] [Abstract][Full Text] [Related]
20. Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells.
Dai Y; Yu C; Singh V; Tang L; Wang Z; McInistry R; Dent P; Grant S
Cancer Res; 2001 Jul; 61(13):5106-15. PubMed ID: 11431348
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
