These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
270 related articles for article (PubMed ID: 20855577)
1. Defining the mechanism of polymerization in the serpinopathies. Ekeowa UI; Freeke J; Miranda E; Gooptu B; Bush MF; Pérez J; Teckman J; Robinson CV; Lomas DA Proc Natl Acad Sci U S A; 2010 Oct; 107(40):17146-51. PubMed ID: 20855577 [TBL] [Abstract][Full Text] [Related]
2. The serpinopathies studying serpin polymerization in vivo. Irving JA; Ekeowa UI; Belorgey D; Haq I; Gooptu B; Miranda E; Pérez J; Roussel BD; Ordóñez A; Dalton LE; Thomas SE; Marciniak SJ; Parfrey H; Chilvers ER; Teckman JH; Alam S; Mahadeva R; Rashid ST; Vallier L; Lomas DA Methods Enzymol; 2011; 501():421-66. PubMed ID: 22078544 [TBL] [Abstract][Full Text] [Related]
3. 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis. Mahadeva R; Dafforn TR; Carrell RW; Lomas DA J Biol Chem; 2002 Mar; 277(9):6771-4. PubMed ID: 11773044 [TBL] [Abstract][Full Text] [Related]
4. Fluorescence correlation spectroscopic study of serpin depolymerization by computationally designed peptides. Chowdhury P; Wang W; Lavender S; Bunagan MR; Klemke JW; Tang J; Saven JG; Cooperman BS; Gai F J Mol Biol; 2007 Jun; 369(2):462-73. PubMed ID: 17442346 [TBL] [Abstract][Full Text] [Related]
5. The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry. Tsutsui Y; Kuri B; Sengupta T; Wintrode PL J Biol Chem; 2008 Nov; 283(45):30804-11. PubMed ID: 18794298 [TBL] [Abstract][Full Text] [Related]
6. alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization. Lomas DA; Elliott PR; Sidhar SK; Foreman RC; Finch JT; Cox DW; Whisstock JC; Carrell RW J Biol Chem; 1995 Jul; 270(28):16864-70. PubMed ID: 7622502 [TBL] [Abstract][Full Text] [Related]
7. Conformational pathology of the serpins: themes, variations, and therapeutic strategies. Gooptu B; Lomas DA Annu Rev Biochem; 2009; 78():147-76. PubMed ID: 19245336 [TBL] [Abstract][Full Text] [Related]
8. Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization. Krishnan B; Gierasch LM Nat Struct Mol Biol; 2011 Feb; 18(2):222-6. PubMed ID: 21258324 [TBL] [Abstract][Full Text] [Related]
9. Parker B. Francis lectureship. Antitrypsin deficiency, the serpinopathies, and chronic obstructive pulmonary disease. Lomas DA Proc Am Thorac Soc; 2006 Aug; 3(6):499-501. PubMed ID: 16921127 [TBL] [Abstract][Full Text] [Related]
10. Sugar and alcohol molecules provide a therapeutic strategy for the serpinopathies that cause dementia and cirrhosis. Sharp LK; Mallya M; Kinghorn KJ; Wang Z; Crowther DC; Huntington JA; Belorgey D; Lomas DA FEBS J; 2006 Jun; 273(11):2540-52. PubMed ID: 16704419 [TBL] [Abstract][Full Text] [Related]
11. New insights into the structural basis of alpha 1-antitrypsin deficiency. Lomas DA QJM; 1996 Nov; 89(11):807-12. PubMed ID: 8977959 [TBL] [Abstract][Full Text] [Related]
12. The molecular aetiology of the serpinopathies. Davies MJ; Lomas DA Int J Biochem Cell Biol; 2008; 40(6-7):1273-86. PubMed ID: 18289918 [TBL] [Abstract][Full Text] [Related]
13. Conformational changes in serpins and the mechanism of alpha 1-antitrypsin deficiency. Carrell RW; Whisstock J; Lomas DA Am J Respir Crit Care Med; 1994 Dec; 150(6 Pt 2):S171-5. PubMed ID: 7952655 [TBL] [Abstract][Full Text] [Related]
14. Hypersensitive mousetraps, alpha1-antitrypsin deficiency and dementia. Lomas DA; Lourbakos A; Cumming SA; Belorgey D Biochem Soc Trans; 2002 Apr; 30(2):89-92. PubMed ID: 12023831 [TBL] [Abstract][Full Text] [Related]
16. Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies. Crowther DC; Belorgey D; Miranda E; Kinghorn KJ; Sharp LK; Lomas DA Eur J Hum Genet; 2004 Mar; 12(3):167-72. PubMed ID: 14694355 [TBL] [Abstract][Full Text] [Related]
17. Unravelling the twists and turns of the serpinopathies. Roussel BD; Irving JA; Ekeowa UI; Belorgey D; Haq I; Ordóñez A; Kruppa AJ; Duvoix A; Rashid ST; Crowther DC; Marciniak SJ; Lomas DA FEBS J; 2011 Oct; 278(20):3859-67. PubMed ID: 21624056 [TBL] [Abstract][Full Text] [Related]
18. Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies. Lomas DA; Belorgey D; Mallya M; Onda M; Kinghorn KJ; Sharp LK; Phillips RL; Page R; Crowther DC; Miranda E Front Biosci; 2004 Sep; 9():2873-91. PubMed ID: 15353322 [TBL] [Abstract][Full Text] [Related]
19. Inhibitory conformation of the reactive loop of alpha 1-antitrypsin. Elliott PR; Lomas DA; Carrell RW; Abrahams JP Nat Struct Biol; 1996 Aug; 3(8):676-81. PubMed ID: 8756325 [TBL] [Abstract][Full Text] [Related]
20. Molecular mousetraps and the serpinopathies. Lomas DA; Belorgey D; Mallya M; Miranda E; Kinghorn KJ; Sharp LK; Phillips RL; Page R; Robertson AS; Crowther DC Biochem Soc Trans; 2005 Apr; 33(Pt 2):321-30. PubMed ID: 15787598 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]