These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 20858721)

  • 1. MLH1 founder mutations with moderate penetrance in Spanish Lynch syndrome families.
    Borràs E; Pineda M; Blanco I; Jewett EM; Wang F; Teulé A; Caldés T; Urioste M; Martínez-Bouzas C; Brunet J; Balmaña J; Torres A; Ramón y Cajal T; Sanz J; Pérez-Cabornero L; Castellví-Bel S; Alonso A; Lanas A; González S; Moreno V; Gruber SB; Rosenberg NA; Mukherjee B; Lázaro C; Capellá G
    Cancer Res; 2010 Oct; 70(19):7379-91. PubMed ID: 20858721
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Spectrum of MLH1 and MSH2 mutations in Chilean families with suspected Lynch syndrome.
    Alvarez K; Hurtado C; Hevia MA; Wielandt AM; de la Fuente M; Church J; Carvallo P; López-Köstner F
    Dis Colon Rectum; 2010 Apr; 53(4):450-9. PubMed ID: 20305446
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Germ line MLH1 and MSH2 mutations in Taiwanese Lynch syndrome families: characterization of a founder genomic mutation in the MLH1 gene.
    Tang R; Hsiung C; Wang JY; Lai CH; Chien HT; Chiu LL; Liu CT; Chen HH; Wang HM; Chen SX; Hsieh LL;
    Clin Genet; 2009 Apr; 75(4):334-45. PubMed ID: 19419416
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Detailed characterization of MLH1 p.D41H and p.N710D variants coexisting in a Lynch syndrome family with conserved MLH1 expression tumors.
    Pineda M; González-Acosta M; Thompson BA; Sánchez R; Gómez C; Martínez-López J; Perea J; Caldés T; Rodríguez Y; Landolfi S; Balmaña J; Lázaro C; Robles L; Capellá G; Rueda D
    Clin Genet; 2015 Jun; 87(6):543-8. PubMed ID: 25060679
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.
    Plaschke J; Engel C; Krüger S; Holinski-Feder E; Pagenstecher C; Mangold E; Moeslein G; Schulmann K; Gebert J; von Knebel Doeberitz M; Rüschoff J; Loeffler M; Schackert HK
    J Clin Oncol; 2004 Nov; 22(22):4486-94. PubMed ID: 15483016
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer.
    Sheng JQ; Chan TL; Chan YW; Huang JS; Chen JG; Zhang MZ; Guo XL; Mu H; Chan AS; Li SR; Yuen ST; Leung SY
    Chin J Dig Dis; 2006; 7(4):197-205. PubMed ID: 17054581
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comprehensive functional assessment of MLH1 variants of unknown significance.
    Borràs E; Pineda M; Brieger A; Hinrichsen I; Gómez C; Navarro M; Balmaña J; Ramón y Cajal T; Torres A; Brunet J; Blanco I; Plotz G; Lázaro C; Capellá G
    Hum Mutat; 2012 Nov; 33(11):1576-88. PubMed ID: 22736432
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lynch syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.
    Hesson LB; Packham D; Kwok CT; Nunez AC; Ng B; Schmidt C; Fields M; Wong JW; Sloane MA; Ward RL
    Hum Mutat; 2015 Jun; 36(6):622-30. PubMed ID: 25762362
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional significance and clinical phenotype of nontruncating mismatch repair variants of MLH1.
    Raevaara TE; Korhonen MK; Lohi H; Hampel H; Lynch E; Lönnqvist KE; Holinski-Feder E; Sutter C; McKinnon W; Duraisamy S; Gerdes AM; Peltomäki P; Kohonen-Ccorish M; Mangold E; Macrae F; Greenblatt M; de la Chapelle A; Nyström M
    Gastroenterology; 2005 Aug; 129(2):537-49. PubMed ID: 16083711
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prospective determination of prevalence of lynch syndrome in young women with endometrial cancer.
    Lu KH; Schorge JO; Rodabaugh KJ; Daniels MS; Sun CC; Soliman PT; White KG; Luthra R; Gershenson DM; Broaddus RR
    J Clin Oncol; 2007 Nov; 25(33):5158-64. PubMed ID: 17925543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.
    Lagerstedt Robinson K; Liu T; Vandrovcova J; Halvarsson B; Clendenning M; Frebourg T; Papadopoulos N; Kinzler KW; Vogelstein B; Peltomäki P; Kolodner RD; Nilbert M; Lindblom A
    J Natl Cancer Inst; 2007 Feb; 99(4):291-9. PubMed ID: 17312306
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression defect size among unclassified MLH1 variants determines pathogenicity in Lynch syndrome diagnosis.
    Hinrichsen I; Brieger A; Trojan J; Zeuzem S; Nilbert M; Plotz G
    Clin Cancer Res; 2013 May; 19(9):2432-41. PubMed ID: 23403630
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of new founder Alu-mediated rearrangements in MSH2 gene associated with a Lynch syndrome phenotype.
    Pérez-Cabornero L; Borrás Flores E; Infante Sanz M; Velasco Sampedro E; Acedo Becares A; Lastra Aras E; Cuevas González J; Pineda Riu M; Ramón y Cajal Asensio T; Capellá Munar G; Miner Pino C; Durán Domínguez M
    Cancer Prev Res (Phila); 2011 Oct; 4(10):1546-55. PubMed ID: 21778331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel exonic rearrangement affecting MLH1 and the contiguous LRRFIP2 is a founder mutation in Portuguese Lynch syndrome families.
    Pinheiro M; Pinto C; Peixoto A; Veiga I; Mesquita B; Henrique R; Baptista M; Fragoso M; Sousa O; Pereira H; Marinho C; Moreira Dias L; Teixeira MR
    Genet Med; 2011 Oct; 13(10):895-902. PubMed ID: 21785361
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A founder MLH1 mutation in Lynch syndrome families from Piedmont, Italy, is associated with an increased risk of pancreatic tumours and diverse immunohistochemical patterns.
    Borelli I; Casalis Cavalchini GC; Del Peschio S; Micheletti M; Venesio T; Sarotto I; Allavena A; Delsedime L; Barberis MA; Mandrile G; Berchialla P; Ogliara P; Bracco C; Pasini B
    Fam Cancer; 2014 Sep; 13(3):401-13. PubMed ID: 24802709
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ten novel MSH2 and MLH1 germline mutations in families with HNPCC.
    Krüger S; Bier A; Plaschke J; Höhl R; Aust DE; Kreuz FR; Pistorius SR; Saeger HD; Rothhammer V; Al-Taie O; Schackert HK
    Hum Mutat; 2004 Oct; 24(4):351-2. PubMed ID: 15365996
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nine novel pathogenic germline mutations in MLH1, MSH2, MSH6 and PMS2 in families with Lynch syndrome.
    Rahner N; Friedrichs N; Wehner M; Steinke V; Aretz S; Friedl W; Buettner R; Mangold E; Propping P; Walldorf C
    Acta Oncol; 2007; 46(6):763-9. PubMed ID: 17653898
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assessing the pathogenicity of MLH1 missense mutations in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with clinical, genetic and functional features.
    Belvederesi L; Bianchi F; Loretelli C; Gagliardini D; Galizia E; Bracci R; Rosati S; Bearzi I; Viel A; Cellerino R; Porfiri E
    Eur J Hum Genet; 2006 Jul; 14(7):853-9. PubMed ID: 16724012
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype.
    Kwok CT; Vogelaar IP; van Zelst-Stams WA; Mensenkamp AR; Ligtenberg MJ; Rapkins RW; Ward RL; Chun N; Ford JM; Ladabaum U; McKinnon WC; Greenblatt MS; Hitchins MP
    Eur J Hum Genet; 2014 May; 22(5):617-24. PubMed ID: 24084575
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Three novel germline mutations in MLH1 and MSH2 in families with Lynch syndrome living on Jeju island, Korea.
    Kim YM; Choe CG; Cho SK; Jung IH; Chang WY; Cho M
    BMB Rep; 2010 Oct; 43(10):693-7. PubMed ID: 21034533
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.