BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 20858897)

  • 1. Requirement of TGFbeta signaling for SMO-mediated carcinogenesis.
    Fan Q; He M; Sheng T; Zhang X; Sinha M; Luxon B; Zhao X; Xie J
    J Biol Chem; 2010 Nov; 285(47):36570-6. PubMed ID: 20858897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.
    Gruber W; Hutzinger M; Elmer DP; Parigger T; Sternberg C; Cegielkowski L; Zaja M; Leban J; Michel S; Hamm S; Vitt D; Aberger F
    Oncotarget; 2016 Feb; 7(6):7134-48. PubMed ID: 26784250
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A role for transcription factor STAT3 signaling in oncogene smoothened-driven carcinogenesis.
    Gu D; Fan Q; Zhang X; Xie J
    J Biol Chem; 2012 Nov; 287(45):38356-66. PubMed ID: 22992748
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tumor shrinkage by cyclopamine tartrate through inhibiting hedgehog signaling.
    Fan Q; Gu D; He M; Liu H; Sheng T; Xie G; Li CX; Zhang X; Wainwright B; Garrossian A; Garrossian M; Gardner D; Xie J
    Chin J Cancer; 2011 Jul; 30(7):472-81. PubMed ID: 21718593
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular imaging of TGFβ-induced Smad2/3 phosphorylation reveals a role for receptor tyrosine kinases in modulating TGFβ signaling.
    Nyati S; Schinske K; Ray D; Nyati MK; Ross BD; Rehemtulla A
    Clin Cancer Res; 2011 Dec; 17(23):7424-39. PubMed ID: 21948232
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK.
    Zheng Y; Zhao YD; Gibbons M; Abramova T; Chu PY; Ash JD; Cunningham JM; Skapek SX
    J Biol Chem; 2010 Nov; 285(46):35654-64. PubMed ID: 20826783
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells.
    Fu Y; Chang A; Chang L; Niessen K; Eapen S; Setiadi A; Karsan A
    J Biol Chem; 2009 Jul; 284(29):19452-62. PubMed ID: 19473993
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Requirement of a dynein light chain in TGFbeta/Smad3 signaling.
    Jin Q; Gao G; Mulder KM
    J Cell Physiol; 2009 Dec; 221(3):707-15. PubMed ID: 19711352
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Retinoids regulate TGFbeta signaling at the level of Smad2 phosphorylation and nuclear accumulation.
    Hoover LL; Burton EG; O'Neill ML; Brooks BA; Sreedharan S; Dawson NA; Kubalak SW
    Biochim Biophys Acta; 2008 Dec; 1783(12):2279-86. PubMed ID: 18773928
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function.
    Moutasim KA; Mellows T; Mellone M; Lopez MA; Tod J; Kiely PC; Sapienza K; Greco A; Neill GW; Violette S; Weinreb PH; Marshall JF; Ottensmeier CH; Sayan AE; Jenei V; Thomas GJ
    J Pathol; 2014 Jun; 233(2):196-208. PubMed ID: 24573955
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.
    Sonnylal S; Denton CP; Zheng B; Keene DR; He R; Adams HP; Vanpelt CS; Geng YJ; Deng JM; Behringer RR; de Crombrugghe B
    Arthritis Rheum; 2007 Jan; 56(1):334-44. PubMed ID: 17195237
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway.
    Akool el-S; Doller A; Müller R; Gutwein P; Xin C; Huwiler A; Pfeilschifter J; Eberhardt W
    J Biol Chem; 2005 Nov; 280(47):39403-16. PubMed ID: 16183640
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The transcription factor GLI2 as a downstream mediator of transforming growth factor-β-induced fibroblast activation in SSc.
    Liang R; Šumová B; Cordazzo C; Mallano T; Zhang Y; Wohlfahrt T; Dees C; Ramming A; Krasowska D; Michalska-Jakubus M; Distler O; Schett G; Šenolt L; Distler JH
    Ann Rheum Dis; 2017 Apr; 76(4):756-764. PubMed ID: 27793816
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of hedgehog and vitamin D signaling pathways in basal cell carcinomas.
    Albert B; Hahn H
    Adv Exp Med Biol; 2014; 810():329-41. PubMed ID: 25207374
    [TBL] [Abstract][Full Text] [Related]  

  • 15. GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.
    Atwood SX; Li M; Lee A; Tang JY; Oro AE
    Nature; 2013 Feb; 494(7438):484-8. PubMed ID: 23446420
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interleukin 1 β-induced SMAD2/3 linker modifications are TAK1 dependent and delay TGFβ signaling in primary human mesenchymal stem cells.
    van den Akker GG; van Beuningen HM; Vitters EL; Koenders MI; van de Loo FA; van Lent PL; Blaney Davidson EN; van der Kraan PM
    Cell Signal; 2017 Dec; 40():190-199. PubMed ID: 28943409
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclic AMP enhances TGFβ responses of breast cancer cells by upregulating TGFβ receptor I expression.
    Oerlecke I; Bauer E; Dittmer A; Leyh B; Dittmer J
    PLoS One; 2013; 8(1):e54261. PubMed ID: 23349840
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transforming growth factor-β1 induces type II collagen and aggrecan expression via activation of extracellular signal-regulated kinase 1/2 and Smad2/3 signaling pathways.
    Zhu Y; Tao H; Jin C; Liu Y; Lu X; Hu X; Wang X
    Mol Med Rep; 2015 Oct; 12(4):5573-9. PubMed ID: 26165845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression.
    Schiro MM; Stauber SE; Peterson TL; Krueger C; Darnell SJ; Satyshur KA; Drinkwater NR; Newton MA; Hoffmann FM
    PLoS One; 2011; 6(9):e25021. PubMed ID: 21949838
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Divergence(s) in nodal signaling between aggressive melanoma and embryonic stem cells.
    Khalkhali-Ellis Z; Kirschmann DA; Seftor EA; Gilgur A; Bodenstine TM; Hinck AP; Hendrix MJ
    Int J Cancer; 2015 Mar; 136(5):E242-51. PubMed ID: 25204799
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.