BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 20861124)

  • 1. Familial glucocorticoid resistance caused by a novel frameshift glucocorticoid receptor mutation.
    Trebble P; Matthews L; Blaikley J; Wayte AW; Black GC; Wilton A; Ray DW
    J Clin Endocrinol Metab; 2010 Dec; 95(12):E490-9. PubMed ID: 20861124
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of two novel mutations in the glucocorticoid receptor gene in patients with primary cortisol resistance.
    Ruiz M; Lind U; Gåfvels M; Eggertsen G; Carlstedt-Duke J; Nilsson L; Holtmann M; Stierna P; Wikström AC; Werner S
    Clin Endocrinol (Oxf); 2001 Sep; 55(3):363-71. PubMed ID: 11589680
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel, C-terminal dominant negative mutation of the GR causes familial glucocorticoid resistance through abnormal interactions with p160 steroid receptor coactivators.
    Vottero A; Kino T; Combe H; Lecomte P; Chrousos GP
    J Clin Endocrinol Metab; 2002 Jun; 87(6):2658-67. PubMed ID: 12050230
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.
    Karl M; Lamberts SW; Detera-Wadleigh SD; Encio IJ; Stratakis CA; Hurley DM; Accili D; Chrousos GP
    J Clin Endocrinol Metab; 1993 Mar; 76(3):683-9. PubMed ID: 8445027
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene.
    Huizenga NA; de Lange P; Koper JW; de Herder WW; Abs R; Kasteren JH; de Jong FH; Lamberts SW
    J Clin Endocrinol Metab; 2000 May; 85(5):2076-81. PubMed ID: 10843199
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Female pseudohermaphroditism caused by a novel homozygous missense mutation of the GR gene.
    Mendonca BB; Leite MV; de Castro M; Kino T; Elias LL; Bachega TA; Arnhold IJ; Chrousos GP; Latronico AC
    J Clin Endocrinol Metab; 2002 Apr; 87(4):1805-9. PubMed ID: 11932321
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel point mutation in the ligand-binding domain (LBD) of the human glucocorticoid receptor (hGR) causing generalized glucocorticoid resistance: the importance of the C terminus of hGR LBD in conferring transactivational activity.
    Charmandari E; Raji A; Kino T; Ichijo T; Tiulpakov A; Zachman K; Chrousos GP
    J Clin Endocrinol Metab; 2005 Jun; 90(6):3696-705. PubMed ID: 15769988
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Familial glucocorticoid receptor haploinsufficiency by non-sense mediated mRNA decay, adrenal hyperplasia and apparent mineralocorticoid excess.
    Bouligand J; Delemer B; Hecart AC; Meduri G; Viengchareun S; Amazit L; Trabado S; Fève B; Guiochon-Mantel A; Young J; Lombès M
    PLoS One; 2010 Oct; 5(10):e13563. PubMed ID: 21042587
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel point mutation in helix 10 of the human glucocorticoid receptor causes generalized glucocorticoid resistance by disrupting the structure of the ligand-binding domain.
    Nader N; Bachrach BE; Hurt DE; Gajula S; Pittman A; Lescher R; Kino T
    J Clin Endocrinol Metab; 2010 May; 95(5):2281-5. PubMed ID: 20335448
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucocorticosteroid resistance in humans. Elucidation of the molecular mechanisms and implications for pathophysiology.
    Stratakis CA; Karl M; Schulte HM; Chrousos GP
    Ann N Y Acad Sci; 1994 Nov; 746():362-74; discussion 374-6. PubMed ID: 7825890
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generalized glucocorticoid resistance caused by a novel two-nucleotide deletion in the hormone-binding domain of the glucocorticoid receptor gene NR3C1.
    Donner KM; Hiltunen TP; Jänne OA; Sane T; Kontula K
    Eur J Endocrinol; 2013 Jan; 168(1):K9-K18. PubMed ID: 23076843
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Familial/sporadic glucocorticoid resistance: clinical phenotype and molecular mechanisms.
    Charmandari E; Kino T; Chrousos GP
    Ann N Y Acad Sci; 2004 Jun; 1024():168-81. PubMed ID: 15265781
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pathologic human GR mutant has a transdominant negative effect on the wild-type GR by inhibiting its translocation into the nucleus: importance of the ligand-binding domain for intracellular GR trafficking.
    Kino T; Stauber RH; Resau JH; Pavlakis GN; Chrousos GP
    J Clin Endocrinol Metab; 2001 Nov; 86(11):5600-8. PubMed ID: 11701741
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Natural glucocorticoid receptor mutants causing generalized glucocorticoid resistance: molecular genotype, genetic transmission, and clinical phenotype.
    Charmandari E; Kino T; Souvatzoglou E; Vottero A; Bhattacharyya N; Chrousos GP
    J Clin Endocrinol Metab; 2004 Apr; 89(4):1939-49. PubMed ID: 15070967
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glucocorticoid resistance in premature pubarche and adolescent hyperandrogenism.
    Witchel SF; Smith RR
    Mol Genet Metab; 1999 Feb; 66(2):137-41. PubMed ID: 10068517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The N363S and I559N single nucleotide polymorphisms of the h-GR/NR3C1 gene in patients with bronchial asthma.
    Panek M; Pietras T; Antczak A; Fabijan A; Przemęcka M; Górski P; Kuna P; Szemraj J
    Int J Mol Med; 2012 Jul; 30(1):142-50. PubMed ID: 22469783
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Further characterization of human glucocorticoid receptor mutants, R477H and G679S, associated with primary generalized glucocorticoid resistance.
    Ruiz M; Hedman E; Gåfvels M; Eggertsen G; Werner S; Wahrenberg H; Wikström AC
    Scand J Clin Lab Invest; 2013 Apr; 73(3):203-7. PubMed ID: 23391271
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GRKO mice express an aberrant dexamethasone-binding glucocorticoid receptor, but are profoundly glucocorticoid resistant.
    Cole TJ; Myles K; Purton JF; Brereton PS; Solomon NM; Godfrey DI; Funder JW
    Mol Cell Endocrinol; 2001 Feb; 173(1-2):193-202. PubMed ID: 11223190
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant and wild-type androgen receptors exhibit cross-talk on androgen-, glucocorticoid-, and progesterone-mediated transcription.
    Yen PM; Liu Y; Palvimo JJ; Trifiro M; Whang J; Pinsky L; Jänne OA; Chin WW
    Mol Endocrinol; 1997 Feb; 11(2):162-71. PubMed ID: 9013763
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A hotspot in the glucocorticoid receptor DNA-binding domain susceptible to loss of function mutation.
    Banuelos J; Shin SC; Lu NZ
    Steroids; 2015 Apr; 96():115-20. PubMed ID: 25676786
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.