135 related articles for article (PubMed ID: 20861166)
1. The molecular basis of Lmo2-induced T-cell acute lymphoblastic leukemia.
Curtis DJ; McCormack MP
Clin Cancer Res; 2010 Dec; 16(23):5618-23. PubMed ID: 20861166
[TBL] [Abstract][Full Text] [Related]
2. Of mice and men: how an oncogene transgresses the limits and predisposes to T cell acute lymphoblastic leukemia.
Hoang T
Sci Transl Med; 2010 Mar; 2(21):21ps10. PubMed ID: 20374994
[TBL] [Abstract][Full Text] [Related]
3. The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal.
McCormack MP; Young LF; Vasudevan S; de Graaf CA; Codrington R; Rabbitts TH; Jane SM; Curtis DJ
Science; 2010 Feb; 327(5967):879-83. PubMed ID: 20093438
[TBL] [Abstract][Full Text] [Related]
4. Identification of the LMO4 gene encoding an interaction partner of the LIM-binding protein LDB1/NLI1: a candidate for displacement by LMO proteins in T cell acute leukaemia.
Grutz G; Forster A; Rabbitts TH
Oncogene; 1998 Nov; 17(21):2799-803. PubMed ID: 9840944
[TBL] [Abstract][Full Text] [Related]
5. Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies.
Treanor LM; Volanakis EJ; Zhou S; Lu T; Sherr CJ; Sorrentino BP
Blood; 2011 May; 117(20):5453-62. PubMed ID: 21427293
[TBL] [Abstract][Full Text] [Related]
6. CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells.
Yamazaki H; Nishida H; Iwata S; Dang NH; Morimoto C
Biochem Biophys Res Commun; 2009 May; 383(2):172-7. PubMed ID: 19341705
[TBL] [Abstract][Full Text] [Related]
7. Early T cell differentiation lessons from T-cell acute lymphoblastic leukemia.
Tremblay CS; Hoang T; Hoang T
Prog Mol Biol Transl Sci; 2010; 92():121-56. PubMed ID: 20800819
[TBL] [Abstract][Full Text] [Related]
8. Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
Tatarek J; Cullion K; Ashworth T; Gerstein R; Aster JC; Kelliher MA
Blood; 2011 Aug; 118(6):1579-90. PubMed ID: 21670468
[TBL] [Abstract][Full Text] [Related]
9. [Demonstration of leukemic stem cells in the human T-ALLs and study of the involvement of the NOTCH, TAL1 and ERK/MAPK pathways in human T-leukemogenesis].
Gerby B; Armstrong F; Brunet de la Grange P; Calvo J; Ballerini P; Pflumio F
Ann Pathol; 2008 Nov; 28 Spec No 1(1):S28-9. PubMed ID: 18984291
[No Abstract] [Full Text] [Related]
10. Gene therapy: is IL2RG oncogenic in T-cell development?
Pike-Overzet K; de Ridder D; Weerkamp F; Baert MR; Verstegen MM; Brugman MH; Howe SJ; Reinders MJ; Thrasher AJ; Wagemaker G; van Dongen JJ; Staal FJ
Nature; 2006 Sep; 443(7109):E5; discussion E6-7. PubMed ID: 16988660
[TBL] [Abstract][Full Text] [Related]
11. ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms.
Goossens S; Wang J; Tremblay CS; De Medts J; T'Sas S; Nguyen T; Saw J; Haigh K; Curtis DJ; Van Vlierberghe P; Berx G; Taghon T; Haigh JJ
Haematologica; 2019 Aug; 104(8):1608-1616. PubMed ID: 30679322
[TBL] [Abstract][Full Text] [Related]
12. Assembly of the oncogenic DNA-binding complex LMO2-Ldb1-TAL1-E12.
Ryan DP; Duncan JL; Lee C; Kuchel PW; Matthews JM
Proteins; 2008 Mar; 70(4):1461-74. PubMed ID: 17910069
[TBL] [Abstract][Full Text] [Related]
13. Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Krivtsov AV; Twomey D; Feng Z; Stubbs MC; Wang Y; Faber J; Levine JE; Wang J; Hahn WC; Gilliland DG; Golub TR; Armstrong SA
Nature; 2006 Aug; 442(7104):818-22. PubMed ID: 16862118
[TBL] [Abstract][Full Text] [Related]
14. Cancer stem cells in solid tumors.
Ailles LE; Weissman IL
Curr Opin Biotechnol; 2007 Oct; 18(5):460-6. PubMed ID: 18023337
[TBL] [Abstract][Full Text] [Related]
15. Targeting LMO2 with a peptide aptamer establishes a necessary function in overt T-cell neoplasia.
Appert A; Nam CH; Lobato N; Priego E; Miguel RN; Blundell T; Drynan L; Sewell H; Tanaka T; Rabbitts T
Cancer Res; 2009 Jun; 69(11):4784-90. PubMed ID: 19487290
[TBL] [Abstract][Full Text] [Related]
16. Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice.
Shields BJ; Alserihi R; Nasa C; Bogue C; Alexander WS; McCormack MP
Leukemia; 2015 Apr; 29(4):927-38. PubMed ID: 25283843
[TBL] [Abstract][Full Text] [Related]
17. Ldb1 is required for Lmo2 oncogene-induced thymocyte self-renewal and T-cell acute lymphoblastic leukemia.
Li L; Mitra A; Cui K; Zhao B; Choi S; Lee JY; Stamos DB; El-Khoury D; Warzecha C; Pfeifer K; Hardwick J; Zhao K; Venters B; Davé UP; Love PE
Blood; 2020 Jun; 135(25):2252-2265. PubMed ID: 32181817
[TBL] [Abstract][Full Text] [Related]
18. The SCL/TAL1 gene: roles in normal and malignant haematopoiesis.
Robb L; Begley CG
Bioessays; 1997 Jul; 19(7):607-13. PubMed ID: 9230693
[TBL] [Abstract][Full Text] [Related]
19. Mixed lineage leukemia translocations and a leukemia stem cell program.
Faber J; Armstrong SA
Cancer Res; 2007 Sep; 67(18):8425-8. PubMed ID: 17875678
[TBL] [Abstract][Full Text] [Related]
20. SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression.
Herblot S; Steff AM; Hugo P; Aplan PD; Hoang T
Nat Immunol; 2000 Aug; 1(2):138-44. PubMed ID: 11248806
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]