253 related articles for article (PubMed ID: 20864684)
1. Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.
Choi J; Curtis SJ; Roy DM; Flesken-Nikitin A; Nikitin AY
Am J Pathol; 2010 Nov; 177(5):2645-58. PubMed ID: 20864684
[TBL] [Abstract][Full Text] [Related]
2. The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development.
Rubio R; Gutierrez-Aranda I; Sáez-Castillo AI; Labarga A; Rosu-Myles M; Gonzalez-Garcia S; Toribio ML; Menendez P; Rodriguez R
Oncogene; 2013 Oct; 32(41):4970-80. PubMed ID: 23222711
[TBL] [Abstract][Full Text] [Related]
3. Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo.
Rubio R; García-Castro J; Gutiérrez-Aranda I; Paramio J; Santos M; Catalina P; Leone PE; Menendez P; Rodríguez R
Cancer Res; 2010 May; 70(10):4185-94. PubMed ID: 20442289
[TBL] [Abstract][Full Text] [Related]
4. Mesenchymal loss of p53 alters stem cell capacity and models human soft tissue sarcoma traits.
Sorimachi Y; Kobayashi H; Shiozawa Y; Koide S; Nakato R; Shimizu Y; Okamura T; Shirahige K; Iwama A; Goda N; Takubo K; Takubo K
Stem Cell Reports; 2023 May; 18(5):1211-1226. PubMed ID: 37059101
[TBL] [Abstract][Full Text] [Related]
5. Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage.
Berman SD; Calo E; Landman AS; Danielian PS; Miller ES; West JC; Fonhoue BD; Caron A; Bronson R; Bouxsein ML; Mukherjee S; Lees JA
Proc Natl Acad Sci U S A; 2008 Aug; 105(33):11851-6. PubMed ID: 18697945
[TBL] [Abstract][Full Text] [Related]
6. Loss of Stag2 cooperates with EWS-FLI1 to transform murine Mesenchymal stem cells.
El Beaino M; Liu J; Wasylishen AR; Pourebrahim R; Migut A; Bessellieu BJ; Huang K; Lin PP
BMC Cancer; 2020 Jan; 20(1):3. PubMed ID: 31898537
[TBL] [Abstract][Full Text] [Related]
7. Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice.
Lin PP; Pandey MK; Jin F; Raymond AK; Akiyama H; Lozano G
Carcinogenesis; 2009 Oct; 30(10):1789-95. PubMed ID: 19635748
[TBL] [Abstract][Full Text] [Related]
8. Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia.
Creager AJ; Cohen JA; Geradts J
Cancer Detect Prev; 2001; 25(2):123-31. PubMed ID: 11341347
[TBL] [Abstract][Full Text] [Related]
9. Undifferentiated State Induced by Rb-p53 Double Inactivation in Mouse Thyroid Neuroendocrine Cells and Embryonic Fibroblasts.
Kitajima S; Kohno S; Kondoh A; Sasaki N; Nishimoto Y; Li F; Abdallah Mohammed MS; Muranaka H; Nagatani N; Suzuki M; Kido Y; Takahashi C
Stem Cells; 2015 May; 33(5):1657-69. PubMed ID: 25694388
[TBL] [Abstract][Full Text] [Related]
10. Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.
Matondo RB; Toussaint MJ; Govaert KM; van Vuuren LD; Nantasanti S; Nijkamp MW; Pandit SK; Tooten PC; Koster MH; Holleman K; Schot A; Gu G; Spee B; Roskams T; Rinkes IB; Schotanus B; Kranenburg O; de Bruin A
Oncotarget; 2016 Aug; 7(34):54662-54675. PubMed ID: 27323406
[TBL] [Abstract][Full Text] [Related]
11. Methods to generate genetically engineered mouse models of soft tissue sarcoma.
Dodd RD; Añó L; Blum JM; Li Z; Van Mater D; Kirsch DG
Methods Mol Biol; 2015; 1267():283-95. PubMed ID: 25636474
[TBL] [Abstract][Full Text] [Related]
12. Noncanonical roles of p53 in cancer stemness and their implications in sarcomas.
Curylova L; Ramos H; Saraiva L; Skoda J
Cancer Lett; 2022 Jan; 525():131-145. PubMed ID: 34742870
[TBL] [Abstract][Full Text] [Related]
13. Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas.
Clark-Knowles KV; Senterman MK; Collins O; Vanderhyden BC
PLoS One; 2009 Dec; 4(12):e8534. PubMed ID: 20046869
[TBL] [Abstract][Full Text] [Related]
14. Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells.
Rubio R; Abarrategi A; Garcia-Castro J; Martinez-Cruzado L; Suarez C; Tornin J; Santos L; Astudillo A; Colmenero I; Mulero F; Rosu-Myles M; Menendez P; Rodriguez R
Stem Cells; 2014 May; 32(5):1136-48. PubMed ID: 24446210
[TBL] [Abstract][Full Text] [Related]
15. Generation of Osteosarcomas from a Combination of Rb Silencing and c-Myc Overexpression in Human Mesenchymal Stem Cells.
Wang JY; Wu PK; Chen PC; Lee CW; Chen WM; Hung SC
Stem Cells Transl Med; 2017 Feb; 6(2):512-526. PubMed ID: 28191765
[TBL] [Abstract][Full Text] [Related]
16. A spatially and temporally restricted mouse model of soft tissue sarcoma.
Kirsch DG; Dinulescu DM; Miller JB; Grimm J; Santiago PM; Young NP; Nielsen GP; Quade BJ; Chaber CJ; Schultz CP; Takeuchi O; Bronson RT; Crowley D; Korsmeyer SJ; Yoon SS; Hornicek FJ; Weissleder R; Jacks T
Nat Med; 2007 Aug; 13(8):992-7. PubMed ID: 17676052
[TBL] [Abstract][Full Text] [Related]
17. A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging.
Buchakjian MR; Merritt NM; Moose DL; Dupuy AJ; Tanas MR; Henry MD
PLoS One; 2017; 12(8):e0183469. PubMed ID: 28841687
[TBL] [Abstract][Full Text] [Related]
18. Retinoblastoma protein-initiated cellular growth arrest overcomes the ability of cotransfected wild-type p53 to induce apoptosis.
Shinohara H; Zhou J; Yoshikawa K; Yazumi S; Ko K; Yamaoka Y; Mizukami T; Yoshida T; Akinaga S; Tamaoki T; Motoda H; Benedict WF; Takahashi R
Br J Cancer; 2000 Oct; 83(8):1039-46. PubMed ID: 10993652
[TBL] [Abstract][Full Text] [Related]
19. Human mesenchymal stromal cells do not promote recurrence of soft tissue sarcomas in mouse xenografts after radiation and surgery.
Filomeno PA; Kim KP; Yoon N; Rashedi I; Dayan V; Kandel RA; Wang XH; Felizardo TC; Berinstein E; Jelveh S; Filomeno A; Medin JA; Ferguson PC; Keating A
Cytotherapy; 2018 Aug; 20(8):1001-1012. PubMed ID: 30076069
[TBL] [Abstract][Full Text] [Related]
20. Loss of p53 induces tumorigenesis in p21-deficient mesenchymal stem cells.
Rodriguez R; Rubio R; Masip M; Catalina P; Nieto A; de la Cueva T; Arriero M; San Martin N; de la Cueva E; Balomenos D; Menendez P; García-Castro J
Neoplasia; 2009 Apr; 11(4):397-407. PubMed ID: 19308294
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]